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Patent # | Description |
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2017/0128580 |
TARGETED THERAPEUTICS The present invention provides pharmacological compounds including an effector moiety conjugated to a binding moiety that directs the effector moiety to a... |
2017/0128579 |
METHOD OF SYNTHESIZING POLYSACCHARIDE CONJUGATES AND METHOD FOR CANCER
THERAPY A method of synthesizing a polysaccharide conjugate used for cancer therapy is provided. The method comprises the following steps. A polysaccharide having at... |
2017/0128578 |
PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol... |
2017/0128577 |
SURFACE MODIFIED NANOCRYSTALLINE CELLULOSE AND USES THEREOF The present disclosure relates to surface modified nanocrystalline cellulose (NCC) prepared by chemical modification of NCC as well as its use thereof,... |
2017/0128576 |
ENTERIC ELASTOMERS Enteric elastomers and related methods are generally provided. In some embodiments, the enteric elastomer is a polymer composite. Certain embodiments comprise... |
2017/0128575 |
LIQUID PHARMACEUTICAL FORMULATIONS OF PEMETREXED The present invention provides stable liquid pharmaceutical formulation of pemetrexed or pharmaceutically acceptable salts thereof comprises at least one... |
2017/0128574 |
WATER-SOLUBLE SUPRAMOLECULAR COMPLEXES Water-soluble supramolecular complexes formed from a water soluble block copolymer and at least one associative gelling adjuvant. The copolymer includes at... |
2017/0128573 |
MULTIMODAL THERAPY FOR CANCER CELL DESTRUCTION The field of the disclosure relates generally to cancer cell destruction and, more specifically, to cancer cell destruction by photo-magnetic irradiation... |
2017/0128572 |
LONG-LIVED GADOLINIUM BASED TUMOR TARGETED IMAGING AND THERAPY AGENTS Alkylphosphocholine analogs incorporating a chelating moiety that is chelated to gadolinium are disclosed herein. The alkylphophocholine analogs are compounds... |
2017/0128571 |
MAGNETIC PARTICLE CONTROL Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator.... |
2017/0128570 |
ANNEXIN II COMPOSITIONS AND METHODS The present invention provides compositions and methods that involve the 36 kDa annexin II monomer, which has been identified as having immunostimulatory... |
2017/0128569 |
Engineered Cells Expressing Multiple Immunomodulators and Uses Thereof This invention relates to the field of therapeutics. Most specifically invention provides methods of generating in vitro engineered immune cells conditionally... |
2017/0128568 |
Calcium Flux Agonists And Methods Therefor Calcium flux agonists are used to enhance a TLR- or NOD-mediated stimulus and to so increase an immune response of a host and reduce healing time. Preferred... |
2017/0128567 |
Vaccine Adjuvants The present invention provides a new adjuvant for administering vaccines. |
2017/0128566 |
ALLERGEN DESENSITIZATION METHOD The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method,... |
2017/0128565 |
Methods of Treating CMV Retinitis by T Cell Therapy Disclosed herein are methods of treating CMV (cytomegalovirus) retinitis in a human patient in need thereof, comprising administering to the human patient a... |
2017/0128564 |
POLYPEPTIDE DERIVED FROM gp41, A VACCINE COMPOSITION COMPRISING SAID
POLYPEPTIDE, AND USES FOR TREATING AN... The present invention relates to the field of the in vitro diagnosis of the progression status of an infection of an individual with a virus belonging to the... |
2017/0128563 |
Live Attenuated Classical Swine Fever Vaccine Based in Genetic
Manipulation of a Putative Fusion Peptide Area... The role of a specific E2 region, .sup.869CKWGGNWTCV.sup.878, containing a putative fusion peptide (FP) sequence was evaluated. FPs critically contribute to... |
2017/0128562 |
POLYVALENT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) AND USE AS VACCINES This disclosure provides compositions that include a mixture of viral like particles (VLPs), expressing different individual influenza hemagglutinin (HA)... |
2017/0128561 |
USE OF OIL AND WATER EMULSIONS FOR INCREASING B CELL RESPONSES WITH
MODIFIED VACCINIA ANKARA VIRUS The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to... |
2017/0128560 |
Attenuated Mannheimia haemolytica Vaccines and Methods of Making and Use The present invention provides attenuated M. haemolytica strains that elicit an immune response in animals against M. haemolytica, compositions comprising said... |
2017/0128559 |
CAPSULAR GRAM-POSITIVE BACTERIA BIOCONJUGATE VACCINES The present invention encompasses a novel S. aureus bioconjugate vaccine. More generally, the invention is directed to Gram-positive and other bioconjugate... |
2017/0128558 |
ANTI-MALARIA COMPOSITIONS AND METHODS Described herein are multilayer films that include modified polypeptide epitopes from Plasmodium falciparum, specifically a modified T* epitope. The multilayer... |
2017/0128557 |
Dendritic Cell Therapeutic Agent and Immunotherapeutic Agent Comprising
Peptide Derived from Telomerase, and... Provided is a dendritic cell therapeutic agent, and more particularly, a composition which include dendritic cells activated by peptides including a... |
2017/0128556 |
IMMUNOTHERAPY USING T PRECURSOR CELLS DERIVED FROM PLURIPOTENT STEM CELLS
HAVING REARRANGED T CELL RECEPTOR GENES Provided is a method for immune cell therapy, which comprises generating T cell progenitors from pluripotent stem cells bearing rearranged T cell receptor... |
2017/0128555 |
PLACENTAL COMPOSITIONS FOR STIMULATION OF IMMUNITY TO PD-L1 Disclosed is the new, useful, and unexpected finding that immunization to placental endothelial cells stimulated with interferon gamma result in antibodies to... |
2017/0128554 |
Universal N-Glycan Binding Reagent Methods of capturing N-glycan linked glycomolecules including N-glycans, N-glycopeptides and N-glycoproteins are described. The methods provide substantially... |
2017/0128553 |
Compositions of Engineered Human Arginases and Methods for Treating Cancer Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise... |
2017/0128552 |
METHODS FOR TREATING HEADACHE A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan... |
2017/0128551 |
NOVEL USES OF RECOMBINANT CLOSTRIDIAL NEUROTOXINS WITH DECREASED DURATION
OF EFFECT This invention relates to novel uses of recombinant clostridial neurotoxins exhibiting decreased duration of effect, in particular uses for the treatment of... |
2017/0128550 |
Stabilised Solid Compositions of Factor VII Polypeptides The invention relates to chemically as well as physically stable compositions comprising Factor VII or a Factor VII-related polypeptide such that these... |
2017/0128549 |
COMPLEXES OF RNA AND CATIONIC PEPTIDES FOR TRANSFECTION AND FOR
IMMUNOSTIMULATION The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide, which has the... |
2017/0128548 |
LACTOFERRIN SUPPLEMENTATION AND DIARRHEA The present invention relates in general to the field of intestinal health. In particular, the present inventors have found that a composition comprising... |
2017/0128547 |
Use of Hydrolytic and Oxidative Enzymes to Dissolve Biofilm in Ears A composition for removal of biofilm in the ears is useful for the treatment of ear infections such as otitis media, particularly those infections caused by... |
2017/0128546 |
Therapeutic Charge Engineered Variants of Lysozyme and Methods for Using
Same to Treat Infections The present invention is a genetically engineered version of a lysozyme protein wherein the engineered enzyme exhibits enhanced antimicrodial activity,... |
2017/0128545 |
ALBUMIN NANOPARTICLES TO AUGMENT STEM CELL FUNCTION IN VIVO The present invention relates to a product and method of using albumin nanoparticles for augmenting the function or effectiveness of stem cells or precursor... |
2017/0128544 |
Uses of Humanized Cobra Venom Factor for Reducing or Preventing
Immunogenicity The embodiments herein are concerned with methods and hCVF compositions, including pharmaceutical formulations, useful in complement depletion, the reduction... |
2017/0128543 |
METHODS OF TREATING ANOREXIA NERVOSA BY INTRANASAL ADMINISTRATION OF
INSULIN The present system is directed in several embodiments to a method of administration of a therapeutic composition for treatment of Anorexia Nervosa, safely and... |
2017/0128542 |
NON-AQUEOUS GLUCAGON FORMULATIONS Stabilized glucagon formulations are provided, in the form of a clear solution. The formulations include glucagon in a non-aqueous diluent and an antioxidant... |
2017/0128541 |
NOVEL EXENATIDE ANALOGUE AND USE THEREOF The present invention relates to a novel exenatide analogue, which is an exenatide analogue in which the first to fifteenth amino acids from the C-terminal of... |
2017/0128540 |
EYE DROP FORMULATION An ophthalmic composition for administration to an eye containing 0.001-1000 micrograms per ml by weight of thymosin beta 4 (T.beta.4), or an N-terminal... |
2017/0128539 |
IL-2RBETA-SELECTIVE AGONISTS IN COMBINATION WITH AN ANTI-CTLA-4 ANTIBODY
OR AN ANTI-PD-1 ANTIBODY The invention relates to (among other things) method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) an... |
2017/0128538 |
METHODS FOR ASSESSING THE EFFICACY OF ANTI-INFLAMMATORY CYTOKINE
COMPOSITIONS Methods for generating an anti-inflammatory compositions. Methods include obtaining a biological material, determining input concentrations of an ... |
2017/0128537 |
GCSF FOR USE IN THE TREATMENT OF NEUROGENIC IMMUNE SUPPRESSION AND/OR
PREVENTION OF RELATED MEDICAL COMPLICATIONS The present invention relates to Granulocyte colony-stimulating factor (GCSF) for use in the treatment of neurogenic immune depression syndrome, for use in the... |
2017/0128536 |
NEW PHARMACEUTICAL COMPOSITIONS AND THEIR USE FOR THE TREATMENT OF
AUTOIMMUNE DISORDERS A pharmaceutical composition in which the active substance includes or is: (i) a protein including the sequence SEQ ID NO: 1, representing the APRIL protein,... |
2017/0128535 |
TSLP INDUCES NEUTROPHIL MEDIATED KILLING OF METHICILLIN-RESISTANT
STAPHYLOCOCCUS AUREUS The invention provides a method of promoting the host defense of a patient to a bacterial infection comprising administering to a patient suffering or at risk... |
2017/0128534 |
TREATING ROTATOR CUFF CONDITIONS This document provides methods and materials related to treating rotator cuff conditions (e.g., rotator cuff tendonitis or rotator cuff injuries such as... |
2017/0128533 |
PROTECTION AGAINST APOPTOSIS FROM IONIZING RADIATION The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-.kappa.B activity. The modulators may be... |
2017/0128532 |
Methods For The Prediction Of A Personalized ESA-Dose In The Treatment Of
Anemia The present invention pertains to the use of an Integrative pharmacokinetic/pharmacodynamic (PK/PD) ESA-EpoR mathematical model for calculating the binding... |
2017/0128531 |
TREATING NEURODEGENERATIVE DISEASES WITH PROGRANULIN The invention relates to methods and compositions for treating a neurodegenerative disease. More particularly, the present invention is directed to methods of... |