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Patent # | Description |
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2017/0151270 |
GM-CSF-PRODUCING T-CELL CONTROL AGENT AND Th1/Th2 IMMUNE BALANCE REGULATOR The present invention provides a GM-CSF-producing T-cell control agent comprising a glycolipid compound represented by the following formula (I) or a salt... |
2017/0151269 |
GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics,... |
2017/0151268 |
GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics,... |
2017/0151267 |
COMPOSITIONS AND PRODUCTS FOR USE IN THE TREATMENT OF BONE FRACTURES AND
DEFECTS The invention relates to methods for treatment of bone fractures and defects, in particular to method that accelerate fracture healing, and to compositions,... |
2017/0151266 |
METHODS AND COMPOSITIONS FOR ENHANCED DRUG DELIVERY TO THE EYE AND
EXTENDED DELIVERY FORMULATIONS The present invention comprises compounds and compositions thereof for enhanced drug delivery. Pro-drug and double pro-drug derivatives of corticosteroids... |
2017/0151265 |
PULMONARY INTERSTITIAL PNEUMONIA TREATMENT Model and method of treating inflammatory diseases. Traditional treatments for such diseases include administering to the patient toxic and-inflammatory drugs.... |
2017/0151264 |
COMBINATION The present invention provides a pharmaceutical composition which comprises (a) a compound which is an inhibitor of phosphoinositide 3-kinase delta or a... |
2017/0151263 |
ANORDRIN COMPOSITIONS AND METHODS FOR TREATING DISEASES The present invention provides methods and compositions for treating cancer, reducing side effects, and reducing postmenopausal symptoms comprising anordrin or... |
2017/0151262 |
SHIP INHIBITION TO INDUCE ACTIVATION OF NATURAL KILLER CELLS The present invention relates to the use or SHIP1 inhibitors and pan-SHIP1/2 inhibitors in various methods, including, without limitation, a method of... |
2017/0151261 |
SKIN WOUND HEALING AND SCAR REDUCTION WITH PROSTAGLANDIN EP4 AGONIST
COMBINATIONS A combination of a prostaglandin EP4 agonist and an effective amount of: a prostaglandin EP2 agonist, a skin growth factor, a small peptide, a small inhibitory... |
2017/0151260 |
CHEMICALLY STABLE COMPOSITIONS OF A PHARMACEUTICAL ACTIVE AGENT IN A
MULTI-CHAMBERED DELIVERY SYSTEM FOR... A kit for oromucosally administering a metastable supersaturated solution of a pharmaceutical active agent to a human patient includes a first compartment... |
2017/0151259 |
METHOD FOR THE TREATMENT OF DRAVET SYNDROME A method of treating and/or preventing Dravet Syndrome in a patient such as a patient previously diagnosed with Dravet Syndrome, by administering an effective... |
2017/0151258 |
INTRANASAL BENZODIAZEPINE PHARMACEUTICAL COMPOSITIONS The present invention generally relates to intranasal pharmaceutical compositions comprising a benzodiazepine and methods of use thereof that can provide a... |
2017/0151257 |
METHOD FOR THE TREATMENT OF DRAVET SYNDROME A method of treating and/or preventing Dravet Syndrome in a patient such as a patient previously diagnosed with Dravet Syndrome, by administering an effective... |
2017/0151256 |
ANTITUMOR AGENT To provide a pharmaceutical agent or an antitumor agent useful for the treatment and/or prevention of gastrointestinal cancer, leukemia, pituitary tumor, small... |
2017/0151255 |
METHOD OF TREATING NON-SMALL CELL LUNG CANCER AND/OR SMALL CELL LUNG
CANCER USING THIENOTRIAZOLODIAZEPINE COMPOUNDS A method of treating non-small cell lung cancer and/or small cell lung cancer in a mammal comprises the step of administering to a patient a pharmaceutical... |
2017/0151253 |
Compounds, Compositions, and Methods for Treating Alzheimer's Disease Novel methods and compounds for treating Alzheimer's Disease are provided. In one aspect, the invention provides methods for treating Alzheimer's Disease by... |
2017/0151252 |
2-Amino-6-Methyl-4,4a,5,6-Tetrahydropyrano[3,4-d][1,3]Thiazin-8a(8H)-yl-1,-
3-Thiazol-4-yl Amides The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds... |
2017/0151251 |
INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL
COMPOSITIONS CONTAINING THEM Compounds of formula (I): ##STR00001## wherein R.sub.a, R.sub.b, R.sub.c, R.sub.d, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X, Y and Het are as defined in... |
2017/0151250 |
METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA) The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering... |
2017/0151249 |
COMBINATION THERAPY The present invention relates to methods for treating and/or preventing metabolic diseases comprising the combined administration of a GLP-1 receptor agonist... |
2017/0151248 |
USE OF TRPA1 ANTAGONISTS TO PREVENT OR TREAT INFECTIONS CAUSED BY
BIOLOGICAL-WARFARE AGENTS Provided are methods for preventing and treating injuries caused by exposure to biological warfare agents. The methods include administering to a subject in... |
2017/0151247 |
HSP90 INHIBITORS The disclosure relates to Compounds of Formula (1): ##STR00001## and pharmaceutically acceptable salts thereof wherein Z.sub.1, Z.sub.2, Z.sub.3, Xa, Xb, Xc, Y,... |
2017/0151246 |
METHODS OF EYE TREATMENT USING THERAPEUTIC COMPOSITIONS CONTAINING
DIPYRIDAMOLE A method comprising the step of: administering an effective amount of a topical dipyridamole to a subject in need thereof due to an eye disorder selected from... |
2017/0151245 |
METHODS FOR TREATMENT AND PREVENTION OF TAUOPATHIES AND AMYLOID BETA
AMYLOIDOSIS BY MODULATING CRF RECEPTOR... Methods for treating or preventing tauopathies and/or A.beta. amyloidosis by modulating CRF receptor signaling. Accumulation of hyperphosphorlyated tau protein... |
2017/0151244 |
ORAL PHARMACEUTICAL COMPOSITION OF TOFACITINIB The present invention relates to a dry process for the preparation of pharmaceutical compositions of tofacitinib comprising tofacitinib and one or more... |
2017/0151243 |
Methods for the Treatment of HER2 Amplified Cancer Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib. |
2017/0151242 |
COMPOSITION AND METHOD FOR TREATING OR PREVENTING SKELETAL MUSCLE FIBROSIS A compound in combination with a pharmaceutically acceptable carrier, the compound having a formula: wherein: R1 is a member of the group consisting of... |
2017/0151241 |
METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more... |
2017/0151240 |
F10 Inhibits Growth of PC3 Xenografts and Enhances the Effects of
Radiation Therapy Chemotherapy remains of limited use for the treatment of prostate cancer with only one drug, docetaxel, demonstrating a modest survival advantage for treatment... |
2017/0151239 |
2,4-Pyrimidinediamine Compounds and Their Uses The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical... |
2017/0151238 |
Methods for Treating HCV The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as... |
2017/0151237 |
PHARMACEUTICAL PREPARATION COMPRISING BREXPIPRAZOLE AND SUBSTITUTED
BETA-CYCLODEXTRIN Provided is an aqueous pharmaceutical preparation comprising 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one (compound (I)) or a salt... |
2017/0151236 |
IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN
RECEPTOR USEFUL FOR THE TREATMENT OF... Imidazo[1,2-a]pyridine derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT.sub.2A serotonin receptor.... |
2017/0151235 |
SULPHATE SALTS OF
N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1H-BENZO[d]IMID-
AZOL-2-AMINE,... The present invention relates to sulphate salts of N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1H-benzo[d]imid- azol-2-amine and pharmaceutically... |
2017/0151234 |
6-Hydroxy-2,5,7,8-Tetramethylchroman-Compounds for the Treatment of
Chronic Obstructive Airway Diseases The present invention relates to compounds for the treatment of chronic obstructive airway diseases such as chronic obstructive pulmonary disease (COPD) or... |
2017/0151233 |
METHOD OF TREATING NASOPHARYNGEAL CARCINOMA USING PERILLYL ALCOHOL
DERIVATIVE A method of treating nasopharyngeal carcinoma in a mammal includes delivering to the mammal a therapeutically effective amount of a perillyl alcohol (POH)... |
2017/0151232 |
METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided.... |
2017/0151231 |
NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are... |
2017/0151230 |
NASAL DRUG PRODUCTS AND METHODS OF THEIR USE Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are... |
2017/0151229 |
METHODS OF MANUFACTURING ORAL FORMULATIONS A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a... |
2017/0151228 |
Novel Alpha-Hydroxy Carboxylic Acid and Derivatives and Other GRAS-Based
Prodrugs of Oxymorphone and Uses Thereof The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxymorphone, in a manner that substantially... |
2017/0151227 |
METHODS FOR THE TREATMENT OF ABNORMAL INVOLUNTARY MOVEMENT DISORDERS Disclosed herein are new dosage regimens for deuterium-substituted benzoquinoline compounds, and methods for the treatment of abnormal muscular activity,... |
2017/0151226 |
Treatment of Breast Cancer with Liposomal Irinotecan Provided are methods for treating breast cancer in a patient by administering effective amounts of liposomal irinotecan sucrosofate (MM-398). The breast cancer... |
2017/0151225 |
QUINOLINE DERIVATIVES AND THEIR USE FOR TREATING ENDOPLASMIC RETICULUM
STRESS-RELATED DISEASES AND DISORDERS Provided herein are quinolines, e.g., a compound of Formula I, pharmaceutical compositions thereof, and methods of their use for treating, preventing, or... |
2017/0151224 |
LAQUINIMOD FOR THE TREATMENT OF RELAPSING-REMITTING MULTIPLE SCLEROSIS
(RRMS) PATIENTS WITH A HIGH DISABILITY... This invention provides a method for treating or for reducing ambulatory deterioration in a human patient diagnosed to be afflicted with relapsing-remitting... |
2017/0151223 |
PHARMACEUTICAL COMPOSITION COMBINING AN ANTICONVULSANT AND A DERIVATE OF
NICOTINIC ACID The combination of gabapentin with lysine clonixinate (CLG) makes it possible to relieve neuropathic pain caused both by diabetic neuropathy and by an injury... |
2017/0151222 |
SNORING TREATMENT The present invention features compositions and methods for treatment of snoring. We describe compositions comprising an antihistamine or a pharmaceutically... |
2017/0151221 |
PHARMACEUTICAL COMPOSITIONS COMPRISING CEFEPIME OR SULBACTAM Pharmaceutical compositions comprising a beta-lactam compound selected from cefepime, sulbactam or a pharmaceutically acceptable derivative thereof, and a... |
2017/0151220 |
IBS MICROBIOTA AND USES THEREOF The instant application provides methods of diagnosing and treating a subject having IBS. In certain embodiments, the methods also include diagnosing subjects... |