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Patent # Description
2017/0360918 NOVEL TILAPIA VIRUS AND USES THEREOF
The invention is directed to isolated Tilapia Lake Virus or TiLV, and isolated nucleic acids sequences and polypeptides thereof. The invention also relates to...
2017/0360917 DENGUE VIRUS VACCINE COMPOSITIONS AND METHODS OF USE THEREOF
The present invention relates to dengue virus vaccine compositions comprising a first and a second dengue vaccine, wherein the first dengue vaccine comprises...
2017/0360916 METHOD FOR THE PRODUCTION OF RECOMBINANT VIRUS, DNA CONSTRUCTS, RECOMBINANT VIRUS AND VACCINE COMPOSITIONS
The purpose of the present invention is the production of recombinant virus through the cloning and expression of sequences of coding nucleotides of the whole...
2017/0360915 ADJUVANTING MENINGOCOCCAL FACTOR H BINDING PROTEIN
Factor H binding protein (fHBP) has been proposed for use in immunising against serogroup B meningococcus (`MenB`). This antigen can be efficiently adsorbed to...
2017/0360914 UNIVERSAL CANCER PEPTIDES DERIVED FROM TELOMERASE
The invention relates to a peptide of 15 to 20 amino acids deriving from TERT protein, which peptide is capable of (i) binding to HLA class II and (ii)...
2017/0360913 COMPOSITIONS AND METHODS FOR T CELL DELIVERY OF THERAPEUTIC MOLECULES
The present invention includes compositions and methods for modifying a T cell with a nucleic acid encoding a switch molecule comprising an extracellular...
2017/0360912 CHITOSAN-BASED HYDROGEL AND APPLICATIONS THEREOF.
An hydrogel comprising chitosan and two weak bases having different pKb values. In some embodiments, one of the weak bases if sodium hydrogen carbonate (SHC)....
2017/0360911 TUMOR ANTIGEN PEPTIDE
The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically...
2017/0360910 CS1 TARGETED CHIMERIC ANTIGEN RECEPTOR-MODIFIED T CELLS
Chimeric antigen receptors for use in treating malignant melanoma and other cancers expressing CS1 are described.
2017/0360909 Method for allogeneic cell therapy
A method of manipulating allogeneic cells for use in allogeneic cell therapy providing a composition of highly activated allogeneic T-cells which are infused...
2017/0360908 VACCINE PHARMACEUTICAL COMPOSITION FOR CELL-MEDIATED IMMUNITY CONTAINING BISPHOSPHONATES
The present invention aims to provide a vaccine pharmaceutical composition universally usable for induction of cellular immunity against various antigens and...
2017/0360907 COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING GRAFT VERSUS HOST DISEASE
ILC2 cells play a role in the pathogenesis of graft versus host disease (GvHD) and idiopathic pneumonia syndrome (IPS), both conditions associated with...
2017/0360906 METHODS AND MATERIALS FOR REDUCING CARDIAC XENOGRAFT REJECTION
This document provides methods and materials involved in reducing cardiac xenograft rejection. For example, methods and materials for preparing transgenic pigs...
2017/0360905 Conjugated C1 Esterase Inhibitor and Uses Thereof
The present invention provides, among other things, a conjugated C1-INH for improved treatment of complement-mediated disorders, including hereditary...
2017/0360904 USE OF CLOSTRIDIUM HISTOLYTICUM PROTEASE MIXTURE IN PROMOTING WOUND HEALING
Provided are methods for repairing a wound or inducing the proliferative phase of a wound comprising administering a composition comprising a protease mixture...
2017/0360903 SYSTEMS FOR TREATING DERMAL INFLAMMATORY CONDITIONS
The present invention is directed to novel systems and methods for treating dermal inflammatory disorders, such as psoriasis.
2017/0360902 PHARMACEUTICAL COMPOSITION COMPRISING PLASMINOGEN AND USES THEREOF
Pharmaceutical compositions comprising plasminogen or a biologically active variant thereof are disclosed. In an embodiment, the composition comprises a...
2017/0360901 Alpha-Galactosidase A And 1-Deoxygalactonojirimycin Co-Formulation
The present application provides for compositions comprising .alpha.-galactosidase A in combination with an active site-specific chaperone for the...
2017/0360900 HUMAN ALPHA-GALACTOSIDASE VARIANTS
The present invention provides engineered human alpha-galactosidase polypeptides and compositions thereof. The engineered human alpha-galactosidase...
2017/0360899 TREATING SEIZURE WITH RECOMBINANT ALKALINE PHOSPHATASE
The present disclosure provides a method of treating seizure in a subject having aberrant alkaline phosphatase activities, comprising administering a...
2017/0360898 METHODS AND COMPOSITIONS FOR PROMOTING GLUCOSE HOMEOSTASIS
A method of reducing blood glucose in a subject has been developed. In preferred embodiments, the method involves administering to the subject a specific...
2017/0360897 POLYPEPTIDE AND POLYPEPTIDE COMPLEX FOR SUPPRESSING TUMOR METASTASIS AND TREATING LEUKEMIA AS WELL AS...
The present invention provides a group of polypeptides and a complex formed by the polypeptides and human serum albumin, a method for improving the solubility...
2017/0360896 INFLAMMATORY DISEASE
The present invention is directed to alpha-MSH analogues for treatment of inflammatory disease.
2017/0360894 Oral Administration of Unstable or Poorly-Absorbed Drugs
The disclosure relates to a dosage forms and combinations of dosage forms useful for effective oral administration of drugs which are otherwise unsuitable for...
2017/0360893 CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS
Described are peptide analogs of glucagon, which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to...
2017/0360892 GLUCAGON DERIVATIVES WITH IMPROVED STABILITY
The present invention relates to a novel glucagon derivative peptide, and a composition for preventing or treating hypoglycemia containing the novel glucagon...
2017/0360891 Stable, Benzyl Alcohol-free Aqueous Solution Formulations Containing Alpha-type Interferon
The present invention provides a stable, isotonic, aqueous solution formulation comprising: (i) 0.1-0.5 mg/mL alpha-type interferon, preferably pegylated...
2017/0360890 METHOD FOR REDUCING FLU-LIKE SYMPTOMS ASSOCIATED WITH INTRAMUSCULAR ADMINISTRATION OF INTERFERON USING A FAST...
The present invention provides a method for treating multiple sclerosis (MS), and for reducing flu-like symptoms associated with administration of an...
2017/0360889 NEUREGULIN BASED METHODS AND COMPOSITIONS FOR TREATING CARDIOVASCULAR DISEASES
The present invention relates to compositions and methods for preventing, treating or delaying various cardiovascular diseases or disorders in mammals,...
2017/0360888 METHODS FOR TREATING INFLAMMATORY ARTHRITIS
The invention provides methods and compositions for inhibiting, reducing or slowing inflammation or inflammatory arthritis, for treating inflammatory arthritis...
2017/0360887 ACTIVIN-ACTRII ANTAGONISTS AND USES FOR TREATING ANEMIA
Provided herein are methods for the treatment in a subject of anemia, anemia requiring RBC transfusion, low or intermediate-1-risk myelodysplastic syndromes...
2017/0360886 METHODS FOR TREATING AND PREVENTING CARDIOMYOPATHY
Methods for treating patients having a cardiomyopathy are provided. Additionally, methods for prophylactically treating patients at risk of developing a...
2017/0360885 METHOD OF PREVENTING OR REDUCING THE PROGRESSION OF PROSTATE CANCER
The embodiments include methods of preventing or reducing the progression of prostate cancer in mammals susceptible to developing prostate cancer, and to...
2017/0360884 METHOD FOR TREATING INFLUENZA A VIRUS INFECTION
Disclosed herein is a method of treating influenza A virus (IAV) infection by a fusion protein. According to some embodiments of the present disclosure, the...
2017/0360883 COMPOSITION AND METHOD FOR AFFECTING CYTOKINES AND NF-KB
The present invention discloses a composition and method for effecting various cytokines and NF-.kappa.B by administering an effective amount of a...
2017/0360882 COMPOSITION FOR PREVENTING, IMPROVING OR TREATING PSORIASIS COMPRISING IMMUNOMODULATOR AND GLUCOSAMINE
The present invention relates to a composition for preventing, improving or treating psoriasis containing an immunomodulator and glucosamine. Cyclosporine, an...
2017/0360881 PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF
Provided herein are peptidomimetic macrocycles and methods of using such macrocycles for the treatment of disorders, for example, for treatment of infectious...
2017/0360880 ANTI-AIDS COCKTAIL CONSISTING OF AN ANTI-TUMORAL COMPOUND, A P-GLYCOPROTEIN INHIBITOR, AND AN ANTI-VIRAL AGENT
The invention relates to a cocktail against Aids, consisting of a commercially available anti-tumoral drug (1), such as doxorubicin, idarubicin, etoposide,...
2017/0360879 Novel Cyclic Peptides and Methods Using Same
The present invention includes novel cyclic peptides, and methods of using the same. The present invention further includes novel cyclic peptides conjugated...
2017/0360878 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2017/0360877 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2017/0360876 VASOPRESSIN FORMULATIONS FOR USE IN TREATMENT OF HYPOTENSION
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time...
2017/0360875 METHODS FOR TREATING IMMUNE-MEDIATED VIRAL INFECTIONS
Polypeptides and other compounds that can bind specifically to the C.sub.H2-C.sub.H3 cleft of an immunoglobulin molecule, as well as methods for using such...
2017/0360874 COMBINATION FORMULATION OF THREE ANTIVIRAL COMPOUNDS
Disclosed are pharmaceutical compositions comprising three antiviral compounds. In particular, the pharmaceutical compositions comprise an effective amount of...
2017/0360873 MODULATION AND DETECTION OF A NEURONAL ALTERNATIVE SPLICING REGULATORY NETWORK FOR TREATMENT AND DIAGNOSIS OF...
Methods for treatment and diagnosis of neurological disorders such as autism and autism spectrum disorder are disclosed. Also disclosed are modulators of...
2017/0360872 USE OF UBIQUITIN-PROTEASOME SYSTEM INHIBITORS FOR TREATMENT OF TUMORS ASSOCIATED WITH NEUROFIBROMATOSIS TYPE-2
The invention discloses a method of treating, preventing or ameliorating tumor or symptoms resulting from defective neurofibromatosis type-2 gene in a subject...
2017/0360871 SMALL MOLECULE POLYPEPTIDE FOR PREVENTING AND RESTRAINING INFLAMMATION AND APPLICATION OF SAME
The present invention provides a polypeptide that is rich in leucine and used for preventing and restraining inflammation, and an application of same. The...
2017/0360870 PEPTIDE FOR TREATING OCULAR DISEASES AND COMPOSITION FOR TREATING OCULAR DISEASES COMPRISING SAME
The present specification discloses a pharmaceutical composition for preventing or treating ophthalmopathy. More particularly, disclosed is a composition...
2017/0360869 Composition to Enhance the Bioavailability of Curcumin
A composition having a curcuminoid and an essential oil of turmeric. A composition having a curcuminoid and an essential oil of turmeric, wherein the essential...
2017/0360868 COMPOSITIONS CONTAINING A SPIRANTHES SINENSIS EXTRACT AND PHARMACEUTICAL APPLICATIONS THEREOF
The present disclosure provides compositions and dosage forms comprising sinetirucallol, and methods of using such compositions, such as to treat an...
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