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Patent # Description
2018/0010202 Method for Manufacturing Reduced Iron
Provided is a method for manufacturing reduced iron which includes the steps of: i) drying ores in an ore drier; ii) supplying the dried ores to at least one...
2018/0010198 METHODS OF IDENTIFYING PROLIFERATION SIGNATURES FOR COLORECTAL CANCER
This invention relates methods and compositions for identifying Colorectal Cancer (CRC) prognostic transcripts and groups of CRC prognostic transcripts useful...
2018/0010197 GENE EXPRESSION-BASED BIOMARKER FOR THE DETECTION AND MONITORING OF BRONCHIAL PREMALIGNANT LESIONS
Disclosed herein are assays and methods for the identification of premalignant lesions, as well as methods of determining the likelihood that such premalignant...
2018/0010194 Methods for the Diagnosis of Pancreatic Cancer
The present invention relates to the diagnosis of pancreatic cancer, in particular to a salivary mi RNA for use in the diagnosis of pancreatic cancer.
2018/0010192 LEUKEMIA METHYLATION MARKERS AND USES THEREOF
Disclosed herein are methods and kits for identifying a subject as having leukemia. Also provided herein are methods and kits for determining a leukemia...
2018/0010190 GENETIC VARIANT OF THE ANNEXIN A5 GENE
The present invention relates to a nucleic acid molecule comprising an annexin A5 (ANXA5) gene regulation element which comprises at least one point mutation,...
2018/0010188 METHOD FOR DETECTING NONSENSE-MEDIATED RNA DECAY
Certain embodiments of the invention provide a method of detecting and/or quantitating nonsense mediated RNA decay (NMD) activity in a cell, comprising 1)...
2018/0010187 Biomarkers for Inflammatory Bowel Disease
The present invention provides a method of assessing whether an individual is at high risk or low risk of inflammatory bowel disease (IBD) progression by...
2018/0010186 Estimating Abdominal Aortic Aneurysm (AAA) Expansion Rate Using Clinical And Genetic Data
The present invention relates to methods of identifying and using risk factors for estimating aneurysm expansion, including high risk expansion in abdominal...
2018/0010184 EDITING PROFILING OF PDE8A PRE -MRNA: USE AS SPECIFIC BIOMARKER OF ADARS ACTIVITIES IN HUMAN TISSUES TO...
The present invention relates to the use of the editing profile of PDE8A pre-mRNA as a specific bio marker of ADARs activities in evolved primate, particularly...
2018/0010183 METHODS FOR CHARACTERIZING AND TREATING COGNITIVE IMPAIRMENT IN AGING AND DISEASE
This invention provides methods for identifying genes associated with cognitive impairment and for identifying compounds useful in the treatment of cognitive...
2018/0010181 METHODS AND COMPOSITIONS FOR NANOSTRUCTURE-BASED NUCLEIC ACID SEQUENCING
Provided herein are nanostructure-based sequencing methods and systems.
2018/0010179 METHODS AND DEVICES FOR ANALYZING PARTICLES
Methods, devices and systems for analyzing precious samples of cells, including single cells are provided. The methods, devices, and systems in various...
2018/0010176 METHODS FOR HIGHLY PARALLEL AND ACCURATE MEASUREMENT OF NUCLEIC ACIDS
The current document is directed to methods and compositions that enable simplified, sensitive, and accurate quantification of nucleic acids. Some methods...
2018/0010175 METHODS AND COMPOSITIONS FOR CLONING CIRCULAR RNA
Methods and compositions for in situ detection of circular RNA in a tissue sample are provided.
2018/0010174 MICROSCOPE-FREE IMAGING
Provided herein, in some aspects, are methods of imaging molecules without a microscope or other specialized equipment, referred to herein as "microscope-free...
2018/0010173 Methods for Immobilizing Target Nucleic Acids Utilizing Combinatorial Capture Probes
The present invention provides methods for immobilizing target nucleic acids on a solid support utilizing combinatorial capture probe pairs. These pairs...
2018/0010172 INACTIVATABLE TARGET CAPTURE OLIGOMERS FOR USE IN THE SELECTIVE HYBRIDIZATION AND CAPTURE OF TARGET NUCLEIC...
The present invention provides compositions, kits and methods for the selective hybridization and capture of a specific target nucleic acid. The specific...
2018/0010170 CO-DETECTION AND ASSOCIATION OF MULTIPLE GENES FROM THE SAME GENOME IN A SAMPLE
The present invention is concerned with PCR-based detection methods and kits for the identification, differentiation, and quantification of different bacterial...
2018/0010168 ONE-STEP PROCEDURE FOR THE PURIFICATION OF NUCLEIC ACIDS
The present invention is a new and non-obvious method for the improved and simplified purification of nucleic acids.
2018/0010167 ORGANISM IDENTIFICATION PANEL
Methods and containers are provided for identifying a species, illustratively a bacterial species. Illustrative methods comprise amplifying various genes in...
2018/0010166 FRACTIONAL INITIATOR HYBRIDIZATION CHAIN REACTION
The present disclosure relates to methods and compositions involving HCR reactions that involve initiators that are split into two or more parts. Effective HCR...
2018/0010165 SPECTRAL INTENSITY RATIO (SIR) ANALYSIS FOR RAPID LIVE MICROBIAL ENUMERATION
Single dye fluorescent staining (with a membrane--associated dye such as FM 1-43 or FM 4 -64) and the combination of differences in both intensity and spectral...
2018/0010164 METHODS AND MATERIALS FOR ASSESSING AND TREATING ARTHRITIS
This document provides methods and materials involved in assessing mammals (e.g., humans) for arthritis. For example, methods and materials for assessing a...
2018/0010162 FEED MIXING DEVICE AND ITS USE
Herein is reported a feed mixing device for adding feed solutions with a non-physiologically pH value to a cell cultivation vessel comprising a chamber for...
2018/0010159 METHOD OF PRODUCING SACCHARIDES AND METHOD OF PRODUCING ETHANOL
A method of producing saccharides, in which fluidity of the slurry including biomass can be retained; the used amount of the degrading enzyme can be reduced;...
2018/0010157 GENETICALLY MODIFIED MICROORGANISMS HAVING IMPROVED TOLERANCE TOWARDS L-SERINE
The present invention generally relates to the microbiological industry, and specifically to the production of L-serine or L-serine derivatives using...
2018/0010154 PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL AND FERMENTATION OF SUGARS
The invention relates to an integrated process for alcohol production and organic acid production from lignocellulosic material.
2018/0010152 NOVEL DNA-BINDING PROTEINS AND USES THEREOF
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also...
2018/0010146 REGULATION OF GENE EXPRESSION BY APTAMER-MEDIATED MODULATION OF ALTERNATIVE SPLICING
The invention provides a platform and methods of using the platform for the regulation of the expression of a target gene using exposure to an aptamer ligand...
2018/0010145 MANIPULATION OF DOMINANT MALE STERILITY
Compositions and methods for modulating male fertility in a plant are provided. Compositions comprise nucleotide sequences, and fragments and variants thereof,...
2018/0010142 GENERATION OF PLANTS WITH ALTERED OIL, PROTEIN, OR FIBER CONTENT
The present invention is directed to plants that display an improved oil quantity phenotype or an improved meal quality phenotype due to altered expression of...
2018/0010140 Plants Having Altered Expression and Activity of Yield-Related Proteins
Transgenic plants that have enhanced yield-related traits, such as increased seed oil production, are produced by genetically engineering the plants to...
2018/0010139 METHOD FOR GENE TRANSFER INTO PLANT BELONGING TO GENUS SORGHUM USING AGROBACTERIUM, AND METHOD FOR PRODUCTION...
The problem to be solved by this invention is to provide a method of gene introduction for a genus Sorghum plant and a method for producing a transformed genus...
2018/0010138 OXYGEN-RESPONSIVE BACTERIAL GENE SWITCH
The invention provided herein relates to sequence determinants that elicit certain levels of gene expression and methods for obtaining engineered...
2018/0010137 PRODUCTION OF FATTY ACID DERIVATIVES
The invention relates to compositions and methods, including polynucleotide sequences, amino acid sequences, recombinant host cells and recombinant host cell...
2018/0010136 Methods for Altering Polypeptide Expression
The invention is directed to methods and metric suitable for use in modulating the expression of a polypeptide encoded by a nucleic acid sequence. In certain...
2018/0010135 CIRCULAR NUCLEIC ACID VECTORS, AND METHODS FOR MAKING AND USING THE SAME
Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are...
2018/0010134 DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF THE CRISPR-CAS SYSTEMS AND COMPOSITIONS FOR MODELING COMPETITION...
The invention involves inducing 3-50 or more mutations (e.g., any whole number between 3 and 50 of mutations, with it noted that in some embodiments there can...
2018/0010131 TREATMENT OF ERYTHROPOIETIN (EPO) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO EPO
Oligonucleotide compounds modulate expression and/or function of Erythropoietin (EPO) polynucleotides and encoded products thereof. Methods for treating...
2018/0010130 Double-stranded ribonucleic acid as control against insects
A composition for use in formulations for controlling insect populations, including populations of mosquito and flies. The composition comprises one or more...
2018/0010128 OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN MODULATION OF SMALL NON-CODING RNAs
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric...
2018/0010127 METHOD OF ENHANCING MIR-185 EXPRESSION TO REDUCE LOW DENSITY LIPOPROTEIN/CHOLESTEROL ACCUMULATION IN A CELL
The present invention provides a method of quantifying miR-185 as a potential biomarker in lipid disorder or cardiovascular diseases in human. The present...
2018/0010124 Induction of Hemogenic Endothelium from Pluripotent Stem Cells by Forced Expression of Transcription Factors
Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with...
2018/0010123 COMPOSITIONS AND METHODS FOR PREPARING OLIGONUCLEOTIDE SOLUTIONS
The present invention is directed to methods and compositions for generating a pool of oligonucleotides. The invention finds use in preparing a population or...
2018/0010119 ACCELERATED DIRECTED EVOLUTION OF MICROBIAL CONSORTIA FOR THE DEVELOPMENT OF DESIRABLE PLANT PHENOTYPIC TRAITS
The disclosure relates to methods for the screening, identification, and/or application of one or more microorganisms of use in imparting one or more...
2018/0010117 TARGETED TREATMENT OF LEBER CONGENITAL AMOUROSIS
Disclosed herein are methods and compositions for inactivating mutant genes associated with LCA, using engineered nucleases comprising a DNA binding domain and...
2018/0010116 METHOD OF PRODUCING YEAST EXTRACT
A yeast extract is produced by preparing a suspension containing yeast, applying an electric field treatment to the suspension, and then autolyzing the...
2018/0010112 Polypeptides Having Cellobiohydrolase Activity And Polynucleotides Encoding Same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also...
2018/0010109 POLYPEPTIDE FRAGMENTS COMPRISING ENDONUCLEASE ACTIVITY AND THEIR USE
The present invention relates to polypeptide fragments comprising an amino-terminal fragment of the PA subunit of a viral RNA-dependent RNA polymerase or...
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