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Patent # Description
2018/0140684 MODULATION OF MUSCLE AND ADIPOCYTE DISTRIBUTION AND FATE
Modulation of the ADAMTS1 signaling pathway alters the commitment of progenitor cells to a muscle fate; and increases muscle mass.
2018/0140683 Methods, Compounds, and Compositions For Treatment and Prophylaxis in the Respiratory Tract
The present invention provides a method of reducing the quantity of mucus in the respiratory tract of a subject with elevated levels of mucus in said...
2018/0140682 GENE EDITING METHODS AND COMPOSITIONS FOR ELIMINATING RISK OF JC VIRUS ACTIVATION AND PML (PROGRESSIVE...
A method of eliminating the risk of JCV activation in a subject undergoing immunosuppressive therapy, by administering an effective amount of a gene editing...
2018/0140681 COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASE, CONTAINING SSU72 AS ACTIVE INGREDIENT
The present disclosure relates to a composition for preventing or treating an autoimmune disease, in which the composition includes Ssu72 as an active...
2018/0140680 NANOREACTOR USING POLYION COMPLEX POLYMERSOMES, AND METHOD FOR PRODUCING SAME
The present invention provides a nanoreactor (nano size reaction field) using a polyion complex polymersome and a method for producing the nanoreactor. The...
2018/0140679 MODULATION OF AXL RECEPTOR ACTIVITY IN COMBINATION WITH CYTOREDUCTIVE THERAPY
Compositions and methods are provided for treating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits AXL...
2018/0140678 Directed Stem Cell Recruitment
The invention is directed to methods of inducing cell recruitment and tissue regeneration at a target site in a subject. It is also based, in part, on the...
2018/0140677 ENHANCED MELANOMA CANCER PREVENTION BY NOVEL MELANOTROPINS
A gamma-melanocyte stimulating hormone (.gamma.-MSH) derivative having improved stability, selectivity and bioavailabilty. The .gamma.-MSH derivative is...
2018/0140676 RAPID-ACTING INSULIN COMPOSITIONS
The invention is a pharmaceutical composition of human insulin or insulin analog that includes citrate, treprostinil and stabilizing agents, that has faster...
2018/0140675 Combination Of Dopamine Agonists Plus First Phase Insulin Secretagogues For The Treatment Of Metabolic Disorders
The present invention is directed to a method of treating a metabolic disorder or key elements of a metabolic disorder such method comprising the use of an...
2018/0140674 COMBINATION OF TOLEROGENIC PEPTIDES AND TFG-B FOR USE IN THE INDUCTION AND MAINTENANCE OF ORAL TOLERANCE IN...
This invention relates to the administration of a combination of TGF-.beta. and one or more peptides comprising specific sequences of .beta.-lacto-globulin....
2018/0140673 FGF21 Derivatives and Uses Thereof
The invention relates to a derivative of a FGF21 protein having a cysteine residue at a position corresponding to position 167, 169, 170, 171, 172, 173, 174,...
2018/0140672 ADMINISTRATION OF GROWTH FACTORS FOR THE TREATMENT OF CNS DISORDERS
A method and system that is directed to the local delivery of growth factors to the mammalian CNS to treat CNS disorders associated with neuronal death and/or...
2018/0140671 COMPOSITIONS AND METHODS FOR CARDIAC TISSUE REPAIR
The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more...
2018/0140670 COMPOSITIONS, ARTICLES OF MANUFACTURE AND METHODS FOR TREATING CANCER
A method of treating cancer in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of...
2018/0140669 COMPOSITIONS AND METHODS FOR ENHANCING PEPTIDE STABILITY AGAINST PROTEASE DIGESTION
The present invention relates to the digestion of peptides by pancreatic proteases and, more specifically, to compositions and methods for protecting against...
2018/0140668 METHODS FOR TREATING RESTENOSIS USING ANNEXIN A5
A method for the prophylaxis or treatment of restenosis comprising administering a therapeutically effective amount of Annexin A5 or a functional analogue or...
2018/0140667 UBIQUITIN LIGASE KPC1 PROMOTES PROCESSING OF P105 NF-KAPPAB1 TO P50, ELICITING STRONG TUMOR SUPPRESSION
The invention provides a method for treating cancer comprising the step of administering a therapeutically effective amount of KPC1, a peptide which is at...
2018/0140666 FLAGELLIN FUSION PROTEINS AND CONJUGATES COMPRISING PNEUMOCOCCUS ANTIGENS AND METHODS OF USING THE SAME
The present invention is based, in part, on flagellin adjuvant used to enhance immune responses directed against Streptococcus pneumoniae, in particular, to...
2018/0140665 IMMUNOMODULATORY & ONCOLYTIC MINICELLS AND METHODS OF USE
Disclosed herein are compositions comprising immunomodulatory and oncolytic eubacterial minicells, and the use of the composition in immunomodulatory therapies...
2018/0140664 METHODS, REAGENTS AND KITS FOR DETECTING MINIMAL RESIDUAL DISEASE
The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment...
2018/0140663 FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF
The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described.
2018/0140662 Sustained Release Formulation Comprising Octreotide and Two or More Polylactide-co-glycolide Polymers
The present invert on relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and...
2018/0140661 PEPTIDE INHIBITORS OF TWIST
The disclosure provides, inter alia, compositions comprising TWIST peptide inhibitors and optionally one or more anti-cancer agents, and methods of using the...
2018/0140660 COMPOSITIONS AND METHODS FOR TREATING CANCER
Use of a CXCR4 antagonistic peptide and an immune-check point regulator in the treatment of cancer is provided. Accordingly there is provided a method of...
2018/0140659 ANALOGS OF C5a AND METHODS OF USING SAME
Materials and methods for treating an infection or disease, activating an immune cell at a site of infection or disease, and for directly killing ...
2018/0140658 A METHOD OF TREATING A WOUND, COMPRISING THE STEP OF ADMINISTERING A COMPOSITION INCLUDING A SUBSTANCE P
Provided are a pharmaceutical composition for wound healing including a surfactant, an antioxidant, a thickener, and SP, a method of treating a wound including...
2018/0140657 COMPOSITIONS AND METHODS FOR TREATING CANCER AND PERSISTENT VIRAL INFECTIONS
The methods and compounds disclosed herein are useful in treating a subject having cancer or a viral infection by modulating the innate and adaptive immune...
2018/0140656 SHORT SYNTHETIC PEPTIDE FOR THE TREATMENT AND/OR PROPHYLAXIS OF AUTOIMMUNE AND INFLAMMATORY DISORDERS
Disclosed herein are synthetic peptides and compositions comprising the same, for the treatment and/or prophylaxis of a disease, disorder and/or a condition...
2018/0140654 COMPOSITIONS AND METHODS FOR TREATMENT OF ALCOHOL INDUCED LIVER INJURY
Methods for treating alcohol induced liver injury include administering to a subject an effective amount of a ginger-derived nanoparticle. Methods for...
2018/0140653 COMPOSITIONS, KITS AND METHODS FOR TREATING TYPE II DIABETES MELLITUS
Disclosed herein are methods for treating type II diabetes mellitus. In particular, the present invention relates to methods of using an extract of Hedychium...
2018/0140652 HAND WRAP INCLUDING EUCALYPTUS OIL
Hand wrap includes eucalyptus oil absorbed in a roll of fabric material.
2018/0140651 COMPOSITION FOR PREVENTING OR TREATING LIVER DISEASE COMPRISING POGOSTEMONIS HERBA EXTRACT
The present invention relates to a composition having a Pogostemonis Herba extract which can be effectively used for preventing or treating liver disease. It...
2018/0140650 ISOLATION OF OMEGA-7 FATTY ACID ETHYL ESTERS FROM NATURAL OILS
Methods of producing high purity palmitoleic acid esters from natural oils are disclosed. The natural oils may comprise plant oil, nut oil, microalgae oil, and...
2018/0140649 ONCOLYTIC ADENOVIRUS ENCODING A B7 PROTEIN
The present disclosure provides a replication competent oncolytic adenovirus with selectivity for cancer cells, wherein the adenovirus comprises a transgene...
2018/0140648 BACTERIAL POPULATIONS FOR PROMOTING HEALTH
A method of improving the glucose response in glucose tolerant and intolerant subjects is provided. The method comprises providing to the subject probiotic...
2018/0140647 Delivery System and Probiotic Composition for Animals and Plants
Probiotic compositions that comprise one or more bacteria species in spore form, a thickener to form a stabilized suspension and to preferably act as a...
2018/0140646 FERMENTED COMPOSITION FOR RELIEVING ATOPIC DERMATITIS CONTAINING NATURAL EXTRACTS
Provided is a composition for external skin application, the composition configured for relieving atopic dermatitis, including a mixed extract consisting of a...
2018/0140645 PROBIOTIC OR PREBIOTIC, METHOD FOR PRODUCING SAME, MICROBIAL PREPARATION, HEALTH FOOD, AND MEDICINE
The diatheses of animals vary depending on genetic backgrounds of the animals, and the microbial structure of an enterobacterial flora inherent in a host and...
2018/0140644 BEE-INGESTIBLE COMPOSITIONS, METHODS OF USING SAME FOR PRODUCING HONEY AND HONEY PRODUCED THEREBY
A bee ingestible composition comprising a bee food base and THC and/or CBD is provided. Also provided are methods of producing honey, honey obtainable by these...
2018/0140643 URINARY SYSTEM SYMPTOM AMELIORATION AGENT
The present invention provides a urinary organ symptoms improving agent comprising propolis or a processed product thereof as an active ingredient.
2018/0140642 MICROVESICLES ISOLATED FROM MESENCHYMAL STEM CELLS FOR USE AS IMMUNOSUPPRESSIVE AGENTS
The present invention concerns microvesicles isolated from mesenchymal stem cells as immunosuppressive agents for treatment of inflammatory and immune...
2018/0140641 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS
Formulations of human amniotic fluid and methods of use thereof for treatment of lung disorders, and/or injuries have been developed. The formulations are...
2018/0140640 IMPROVED CONTRACEPTIVE METHODS AND COMPOSITIONS AND DEVICES FOR USE THEREIN
The invention pertains to improved contraceptive methods based on a reversible pseudo state of the Asherman's syndrome, in which the female body follows the...
2018/0140639 THERAPEUTIC SERUM OBTAINED FROM CO-CULTURED CELLS
A therapeutic serum suitable for inclusion in a cosmetic preparation may be produced by stressing a co-culture including proliferative cells. The co-culture of...
2018/0140638 PROCESS FOR PREPARING AN ANIMAL BRAIN EXTRACT
The present invention refers to a process for preparing an animal brain extract. It also refers to the brain extract obtainable according to said process and...
2018/0140637 EPIDERMAL NEURAL CREST STEM CELLS AS A SOURCE OF SCHWANN CELLS
The application describes compositions, kits, and methods for generating Schwann cells from epidermal neural crest stem cells (EPI-NCSC). Such EPI-NCSC can be...
2018/0140636 EXTRACELLULAR MATRIX FROM PLURIPOTENT CELLS
Isolated extracellular matrix from marrow adherent stromal cells and their descendents, which stimulates the growth and survival of a number of different...
2018/0140635 GENETICALLY-MODIFIED CELLS COMPRISING A MODIFIED HUMAN T CELL RECEPTOR ALPHA CONSTANT REGION GENE
Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has...
2018/0140634 ENHANCING THE EFFECT OF CAR-ENGINEERED T CELLS BY MEANS OF NUCLEIC ACID VACCINATION
The present invention generally embraces the treatment of diseases by targeting cells expressing an antigen on the cell surface. In particular the invention...
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