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| Patent # | Description |
|---|---|
| 2018/0155401 |
Method for the Synthesis of Phycocyanin The invention discloses microorganism cell culture conditions that result in increased cellular and media concentrations of a biological pigment. The invention... |
| 2018/0155400 |
COMPRESSED PATHWAYS FOR NONRIBOSOMAL MOLECULAR BIOSYNTHESIS Provided herein are synthetic pathways from Escherichia coli and Vibrio cholerae genes for the production of new, synthetic nonribosomal peptides, and methods... |
| 2018/0155399 |
TFPI INHIBITORS AND METHODS OF USE The invention provides peptides that bind Tissue Factor Pathway Inhibitor (TFPI), including TFPI-inhibitory peptides, and compositions thereof. Peptide... |
| 2018/0155398 |
Flavivirus-Binding, Entry-Obstructing, Protease-Resistant Peptide (RI57) The invention pertains to inhibitors bindable to regions of a virus. More particularly, the invention relates to inhibitors bindable to regions of flaviviral... |
| 2018/0155396 |
STRUCTURE-BASED PEPTIDE INHIBITORS OF P53 AGGREGATION AS A NEW APPROACH TO
CANCER THERAPEUTICS This invention relates, e.g., to an inhibitory peptide or CPP inhibitor which specifically binds to p53 having an aberrant conformation (e.g., is aggregated or... |
| 2018/0155395 |
PEPTIDOMIMETICS FOR IMAGING THE GHRELIN RECEPTOR The present invention concerns compositions comprising and methods of identification and use of imaging agents. The imaging agents comprise a growth hormone... |
| 2018/0155394 |
CANCER CELL-TARGETING PEPTIDE AND USE THEREOF The present invention relates to a peptide targeting a tumor cell and use of the peptide, and more particularly, to a peptide consisting of SEQ ID NO: 1 to SEQ... |
| 2018/0155393 |
HEPATITIS C VIRUS INHIBITORS The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates. |
| 2018/0155392 |
CYSTARGOLIDE COMPOUNDS AND USES THEREOF There is provided herein compounds of formula I, wherein R.sub.1 is H or linear or branched C.sub.1-C.sub.6 lower alkyl; R.sub.2 is H, linear or branched... |
| 2018/0155391 |
Method for extracting proteins and functional lipid from soybean liquid by
directional continuous catalysis... The present invention relates to fields of continuous directional catalysis of soybean slurry to extract protein and functional oil with nano-magnetic... |
| 2018/0155390 |
SURFACE NEUTRALIZATION OF APATITE The present invention discloses methods of neutralizing apatite surfaces, for example during chromatography and before protein elution. |
| 2018/0155389 |
STEROIDS AND PROTEIN-CONJUGATES THEREOF Described herein protein steroid conjugates that are useful, for example, for the target-specific delivery of glucocorticoids (GCs) to cells. |
| 2018/0155388 |
SELECTIVE PROGESTERONE RECEPTOR MODULATOR (SPRM) REGIMEN The invention is directed to a pharmaceutical composition comprising a progesterone receptor antagonist namely ... |
| 2018/0155387 |
PRODUCTION OF STEROLS Method of recovering sterols from tall oil pitch which contains steryl esters. In the method the tall oil pitch is subjected to a transefterification reaction... |
| 2018/0155386 |
PROGESTERONE ANTAGONISTS Described herein are compounds which either act as pure antiprogestins or as antiprogestins with partial agonistic activity and methods of treating cancer... |
| 2018/0155385 |
NUCLEOTIDES FOR THE TREATMENT OF CANCER The present invention relates to novel nucleoside derivatives, pharmaceutical compositions comprising the compounds, processes of preparation thereof, and... |
| 2018/0155384 |
SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF Disclosed herein are nucleosides, nucleotides and nucleotide analogs, methods of synthesizing the same and methods of treating diseases and/or conditions such... |
| 2018/0155383 |
ORGANOMETALLIC COMPOUNDS USEFUL FOR CHEMICAL PHASE DEPOSITION Organometallic compounds, useful in chemical phase deposition processes, having a structure: [{R.sup.1R.sup.2R.sup.3(A))x-M(CO)y]z, wherein R.sup.1, R.sup.2... |
| 2018/0155382 |
CYTOTOXIC PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC USE Platinum(IV) complexes especially suitable for antitumor therapy and methods for their preparation. Further provided is a method for treating a subject, in... |
| 2018/0155381 |
ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Metal complexes with cyclic ligands having Formula (I), ##STR00001## are disclosed. Ligands with cyclic structure are believed to be beneficial to the rigidity... |
| 2018/0155380 |
PLATINUM COMPLEX, OLED AND APPARATUS FOR PROVIDING VISIBLE EMISSION OR
NEAR-INFRARED EMISSION A platinum complex, an OLED and an apparatus for providing visible emission or near-infrared (NIR) emission using the same are described. The platinum complex... |
| 2018/0155379 |
Ruthenium Precursors For ALD And CVD Thin Film Deposition And Uses Thereof Metal coordination complexes comprising a metal atom coordinated to at least one diazabutadiene ligand having a structure represented by: ##STR00001## where each... |
| 2018/0155378 |
ANTIBACTERIAL BISMUTH COMPLEXES Provided herein are organobismuth (III) phosphinate complexes, which comprise a phosphinate group and an aromatic carbocyclyl or aromatic heterocyclyl group.... |
| 2018/0155377 |
NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are... |
| 2018/0155376 |
ALLYL-PHENOXY-CYCLOPHOSPHAZENE COMPOUND, AND PRODUCTION METHOD THEREFOR An object of the present invention is to provide a mixture of cyclophosphazenes suitably substituted with phenoxy having a polymerizable functional group, such... |
| 2018/0155375 |
NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are... |
| 2018/0155374 |
BISPHOSPHONATES VINYLIC MONOMERS AND POLYMERS AND USES THEREOF A compound or a polymer is claimed. A first formula can be ##STR00001## wherein X is H, CH.sub.3, CN, phenyl, substituted phenyl, (CH.sub.2).sub.mZ, or... |
| 2018/0155373 |
Cysteine-Modifying Substrate Analogue Inhibitors of Ribose 5-Phosphate
Isomerase for Parasitic Diseases, Along... Compounds are generally provided, along with pharmaceutical compositions including such compounds. Methods are also generally provided for inhibiting ribose... |
| 2018/0155372 |
TIN COMPOUND, METHOD OF SYNTHESIZING THE SAME, TIN PRECURSOR COMPOUND FOR
ATOMIC LAYER DEPOSITION, AND METHOD... A tin compound, tin precursor compound for atomic layer deposition (ALD), a method of forming a tin-containing material film, and a method of synthesizing a... |
| 2018/0155371 |
PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE A process for preparing an acryloyloxysilane, comprising: reacting a metal salt of a carboxylic acid having the formula ... |
| 2018/0155370 |
THERMOSETTING ALKOXYSILYL COMPOUND HAVING TWO OR MORE ALKOXYSILYL GROUPS,
COMPOSITION AND CURED PRODUCT... The present invention relates to: a thermosetting alkoxysilyl compound (hereinafter, referred to as "alkoxysilyl compound")having two or more alkoxysilyl... |
| 2018/0155369 |
A PROCESS FOR THE PREPARATION OF BIS(CHLOROMETHYL)DICHLOROSILANE AND
BIS(CHLOROMETHYL)(ARYL)CHLOROSILANE The instant invention provides a process for the preparation of bis(chloromethyl)dichlorosilane (BCMCS) or bis(chloromethyl) (aryl)chlorosilane (BCMACS)... |
| 2018/0155368 |
METHOD FOR PREPARING L-BPA Provided is a method for preparing L-BPA, which includes steps of: reacting N-protected (S)-4-halophenylalanine of Formula I, a boronating agent, Grignard... |
| 2018/0155367 |
ETP DERIVATIVES Provided herein, inter alia, is the synthesis of ETP derivatives. The uses of the ETP derivatives described herein include treatment of cancer. |
| 2018/0155366 |
THIAZOLOPYRIMIDINONE COMPOUNDS AND PREPARATION METHODS AND USE THEREOF The present invention provides structural details of a thiazolopyrimidinone compound, a preparation method thereof, and use thereof in the manufacture of a... |
| 2018/0155365 |
TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS The present invention relates to Tetracyclic Heterocycle Compounds of Formula (I). ##STR00001## and pharmaceutically acceptable salts or prodrug thereof, ... |
| 2018/0155364 |
NOVEL PROCESS FOR THE PREPARATION OF DOLUTEGRAVIR AND PHARMACEUTICALLY
ACCEPTABLE SALTS THEREOF The present invention relates to a novel process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof using novel intermediates. |
| 2018/0155363 |
COMPOUNDS FOR THE TREATMENT OF ISCHEMIA-REPERFUSION-RELATED DISEASES The present invention relates to compounds of formula (I) useful in the treatment of ischemia-reperfusion-related pathologies. |
| 2018/0155362 |
MCL-1 INHIBITORS AND METHODS OF USE THEREOF Disclosed is a compound which is 17-chloro-5,13,14,22-tetramethyl-28-oxa-2,9-dithia-5,6,12,13,22-pentaazah- ... |
| 2018/0155361 |
PALLADIUM-MEDIATED KETOLIZATION Provided herein are palladium-mediated coupling reactions useful in the preparation of ketone-containing organic molecules. The provided methods can be used... |
| 2018/0155360 |
ETHER ANALOGUES OF GALIELLALACTONE Ether analogues of galiellalactone, methods of preparing the analogues, and use of the analogues in the treatment of cancer are disclosed. The analogues are of... |
| 2018/0155359 |
SHIP1 MODULATORS AND METHODS RELATED THERETO Compounds of formula (II): ##STR00001## wherein ##STR00002## R.sup.1, R.sup.2, R.sup.5 and R.sup.13 are described herein, or a stereoisomer, enantiomer or... |
| 2018/0155358 |
ERTUGLIFLOZIN CO-CRYSTALS AND PROCESS FOR THEIR PREPARATION The present invention relates to processes for the preparation of an ertugliflozin-L-pyroglutamic acid (1:1) and co-crystal ertugliflozin-L-proline (1:1)... |
| 2018/0155357 |
ISOSORBIDE DIESTER AS PEARLIZING AGENT AND OPACIFIER A description is given of a composition comprising at least one isosorbide diester, at least one isosorbide monoester and at least one fatty acid, and also of... |
| 2018/0155356 |
Crystals of Dispiropyrrolidine Derivatives Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of ... |
| 2018/0155355 |
CRYSTALS OF DISPIROPYRROLIDINE DERIVATIVES Crystals of a dispiropyrrolidine compound or a salt thereof which inhibits the action of Mdm2 are provided. The present invention provides crystals of ... |
| 2018/0155354 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of... |
| 2018/0155353 |
Antimicrobial Compounds and Methods Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking... |
| 2018/0155352 |
CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pi- ... |
| 2018/0155351 |
PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment... |
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