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Patent # Description
2018/0187265 METHODS AND COMPOSITIONS FOR CORRELATING GENETIC MARKERS WITH PROSTATE CANCER RISK
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample...
2018/0187264 MARKERS TO PREDICT MACROCYCLIC LACTONE DRUG RESISTANCE IN DIROFILARIA IMMITIS, THE CAUSATIVE AGENT OF HEARTWORM...
Disclosed are nucleic acid molecules from the genome of Dirofilaria spp. nematodes that contain single nucleotide polymorphisms related to reduced ...
2018/0187263 KITS FOR DIAGNOSTIC DETECTION AND PREVENTION OF FEEDLOT BOVINE RESPIRATORY DISEASE
Kits for assaying response to platelet-activating factor receptor (PAFR) to stress and/or bacterial challenge, along with various methods for detecting PAFR...
2018/0187262 METHOD FOR DIAGNOSING A NEURODEGENERATIVE DISEASE
The present disclosure relates to methods of assessing whether a subject has or is likely to develop a neurodegenerative disease including determining whether...
2018/0187261 KIT AND METHOD FOR THE DIAGNOSIS/PROGNOSIS OF IDIOPATHIC SCOLIOSIS
The present invention provides a method for diagnosing or detecting Idiopathic Scoliosis, in particular AIS, as well as a method for prognosticating this...
2018/0187260 SYSTEMS AND METHODS FOR OBTAINING BIOLOGICAL MOLECULES FROM A SAMPLE
The present invention relates to a method of creating a biomarker profile, the method comprising the steps of: obtaining a sample of biofluid from a subject,...
2018/0187259 SYSTEM AND METHODS FOR SELECTIVE EFFLUENT COLLECTION
A system may include a flow cell through which a plurality of reagents may be pumped during a genetic sequencing operation, an effluent line that, in...
2018/0187258 SINGLE MOLECULE ANALYSIS IN AN ELECTRICAL FIELD
The invention relates to a process and a device for analysing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is...
2018/0187257 BIOMOLECULAR PROCESSING PLATFORM AND USES THEREOF
The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a...
2018/0187256 METHOD FOR CONTROLLING BASE SEQUENCE DETERMINATION, BASE SEQUENCE DETERMINATION SYSTEM AND CONTROL DEVICE
The present disclosure discloses a method for controlling a base sequence determination, a base sequence determination system, and a control device. The base...
2018/0187255 COMMON LINE SELECTOR VALVE FOR A SYSTEM
A system may include a flow cell to support analytes of interest; a selector valve coupled to the flow cell to select a flow path through the flow cell from a...
2018/0187254 METHOD AND KIT FOR DETERMINING THE GENOME INTEGRITY AND/OR THE QUALITY OF A LIBRARY OF DNA SEQUENCES OBTAINED...
A method for determining the integrity of the genome of a sample and/or the quality of a library of DNA sequences obtained by deterministic restriction site...
2018/0187253 PRIMER SET FOR 1,4-DIOXANE-DEGRADING BACTERIA, AND METHOD FOR DETECTING AND QUANTIFYING 1,4-DIOXANE-DEGRADING...
An object of the present invention is to provide a primer that allows for detection and quantification of 1,4-dioxane-degrading bacteria in a quick, highly...
2018/0187252 KINETIC EXCLUSION AMPLIFICATION OF NUCLEIC ACID LIBRARIES
An example method includes reacting a first solution and a different, second solution on a flow cell by flowing the first solution over amplification sites on...
2018/0187251 METHODS OF REDUCING DENSITY-DEPENDENT GC BIAS IN AMPLIFICATION
The invention provides methods for amplifying nucleic acids, particularly methods for reducing density-dependent GC bias and for reducing nucleic acid damage...
2018/0187250 Method of detecting genetic material in a biological sample and a device for its implementation
The object of the invention is a method of detecting genetic material in a biological sample in which the biological sample is loaded into the reaction...
2018/0187249 ELECTRICALLY ACTIVE COMBINATORIAL CHEMICAL (EACC) CHIP FOR BIOCHEMICAL ANALYTE DETECTION
Apparatus and methods are disclosed for electrically active combinatorial-chemical (EACC) chips for biochemical analyte detection. An apparatus includes a...
2018/0187248 GENE SEQUENCING CHIP, GENE SEQUENCING APPARATUS AND GENE SEQUENCING METHOD
The present disclosure provides a gene sequencing chip, a gene sequencing apparatus and a gene sequencing method. The gene sequencing chip comprising: a...
2018/0187247 ASSAY SYSTEMS FOR GENETIC ANALYSIS
The present invention provides assays systems and methods for detection of chromosomal abnormalities and status of single loci associated with monogenic or...
2018/0187246 PROBES AND A METHYLATION IN SITU HYBRIDIZATION ASSAY
The disclosure relates to the field of molecular pathology (for example, cancer diagnosis, prognosis, treatment and/or therapy prediction) through the...
2018/0187245 METHOD AND SYSTEM EMPLOYING DISTINGUISHABLE POLYMERASES FOR DETECTING TERNARY COMPLEXES AND IDENTIFYING COGNATE...
Method of identifying a cognate nucleotide (i.e., the "next correct nucleotide") for a primed template nucleic acid molecule. In some embodiments, an ordered...
2018/0187244 MARKER FOR COMPACT GROWTH IN CUCUMBER
The present invention relates to a marker for identifying a cucumber plant showing a compact growth phenotype, characterized by a shorter internode length...
2018/0187243 METHODS AND APPARATUS FOR SEQUENTIAL AMPLIFICATION REACTIONS
The invention provides methods and apparatus for carrying out multiple amplification reactions in a single reaction chamber by successive cycles of loading...
2018/0187242 SELECTIVE DEGRADATION OF WILD-TYPE DNA AND ENRICHMENT OF MUTANT ALLELES USING NUCLEASE
The present disclosure provides methods for preparing a target mutant nucleic acid for subsequent enrichment relative to a wild type nucleic acid using...
2018/0187241 ACCURATE MOLECULAR DECONVOLUTION OF MIXTURE SAMPLES
The present disclosure relates to methods to deconvolute a mixture sample of genetic material from different origins or sources. The disclosed methods can be...
2018/0187240 DOUBLE-FUNCTIONAL OLIGONUCLEOTIDE COMPRISING COMPLEMENTARY NUCLEOTIDE SEQUENCE, MIS-MATCHED NUCLEOTIDE...
The present disclosure relates to a complementary double-stranded oligo, in which, for the amplification of a particular gene sequence, an inosine linker is...
2018/0187239 TRUNCATED HER2 SRM/MRM ASSAY
This disclosure provides ten (10) specific peptides, and particular peptide characteristics, from the cell membrane-bound Her2 protein and a diagnostic assay...
2018/0187238 SELECTIVE MEDIA AND USES THEREOF
The present embodiments provide for media useful for selection and enrichment of Salmonella species. In a particular embodiment, the medium is a minimal medium...
2018/0187237 PHAGE-MEDIATED IMMUNOASSAY AND METHODS FOR DETERMINING SUSCEPTIBILITY OF BACTERIA TO ANTIBIOTIC OR PROBIOTIC AGENTS
Methods for determining the susceptibility or resistance of bacteria to antibiotic agents are provided. In one embodiment, the methods include culturing the...
2018/0187236 HIGH-THROUGHPUT FLUORESCENT SCREENING ASSAY FOR INHIBITORS OF GRAM-NEGATIVE BACTERIAL IRON UPTAKE
A cell-based assay for identifying a compound that inhibits iron transport in Gram-negative bacteria, engineered bacterial cells, and kits for conducting the...
2018/0187235 Red Blood Cell Dynamics for Administering Treatment for Iron-Deficiency Anemia
Methods for identifying patients with anemia, distinguishing thalassemia-trait anemia from iron-deficiency anemia, and identifying pre-anemic patients several...
2018/0187234 OPTICAL DEVICE FOR IN-LINE AND REAL-TIME MONITORING OF MICROORGANISMS
A multi-wavelength laser diode based optical sensor system capable of monitoring the dynamics and physiological changes of a microorganism culture in...
2018/0187233 SOLARGAS SYSTEM OPERATED IN MULTIPLE MODES
The invention relates to a method and a device for producing biogas in a combined fermenter, in the first section (2) of which organic material is produced by...
2018/0187232 EFFICIENT PRODUCTION OF PEPTIDES
The present invention relates to processes for the production of peptides, and the peptides produced accordingly. Peptides produced according to the invention...
2018/0187231 DESIGNING AN ENZYMATIC PEPTIDE FRAGMENT CONDENSATION STRATEGY
The invention further relates to a process for the enzymatic synthesis of an (oligo)peptide. The invention relates to a method for designing an enzymatic...
2018/0187230 CELL CULTURE PROCESS
Polypeptides having target levels of C-terminal variants are described.
2018/0187229 HIGH EFFICIENCY GENE TRANSFER AND EXPRESSION IN MAMMALIAN CELLS BY A MULTIPLE TRANSFECTION PROCEDURE OF MAR...
The present invention relates to purified and isolated DNA sequences having protein production increasing activity and more specifically to the use of matrix...
2018/0187228 METHOD FOR THE PRODUCTION OF A LYSATE USED FOR CELL-FREE PROTEIN BIOSYNTHESES
The invention relates to a method for producing a lysate used for cell-fee protein biosynthesis, comprising the following steps: a) a genomic sequence in an...
2018/0187227 RNA-MEDIATED GENE ASSEMBLY FROM DNA OLIGONUCLEOTIDES
The present invention is directed to methods and materials for RNA-mediated gene assembly from oligonucleotide sequences. In some embodiments, the...
2018/0187226 AUREOBASIDIUM PULLULANS, CULTURING MEDIUM AND METHOD FOR PRODUCING B-GLUCAN, A CULTURE OF AUREOBASIDIUM...
The present application provides a culture medium for producing .beta.-glucan. The culture medium comprises: a carbon source, lecithin and an ascorbic acid....
2018/0187225 VARIANT LOVD POLYPEPTIDES AND THEIR USES
The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound.
2018/0187224 PROCESSES FOR THE FORMATION OF FURANDICARBOXYLIC ACID (FDCA) VIA A MULTISTEP BIOCATALYTIC OXIDATION REACTION OF...
The present invention relates to processes for the formation of furandicarboxylic acid (FDCA), in particular 2,5-furandicarboxylic acid (2,5-FDCA), and mono-...
2018/0187223 KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF (R)-3-HYDROXYTHIOLANE
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase...
2018/0187222 MICROORGANISMS FOR PRODUCING PUTRESCINE OR ORNITHINE AND PROCESS FOR PRODUCING PUTRESCINE OR ORNITHINE USING THEM
The present invention relates to a recombinant microorganism for producing putrescine or ornithine, and a method for producing putrescine or ornithine using...
2018/0187221 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells...
2018/0187220 Polypeptides Having Peroxygenase Activity
The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates...
2018/0187219 PROCESS FOR THE PREPARATION OF GLYCOLS
A process for the production of glycols comprising: a) providing a feedstock comprising starch; b) subjecting said feedstock to a hydrolysis reaction in the...
2018/0187218 PROCESSING BIOMASS
Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example,...
2018/0187217 Carbonyl reductase oligomers and their application in synthesis of chiral alcohols
Disclosed are methods for the synthesis of chiral alcohols by Sortase A-mediated oxidoreductase oligomers, which relates to the field of biocatalysis. In the...
2018/0187216 USE OF MICROBACTERIUM STRAINS FOR THE PRODUCTION OF ANTIBACTERIAL AGENTS
The present invention relates to the use of a bacterium of the genus Microbacterium for the production of a compound endowed with antibacterial activity.
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