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Patent # Description
2018/0186912 PRODUCING POLYOLEFIN PRODUCTS
Catalyst systems and methods for making and using the same. A method of methylating a catalyst composition while substantially normalizing the entiomeric...
2018/0186911 PRODUCING POLYOLEFIN PRODUCTS
Catalyst systems and methods for making and using the same. A method of methylating a catalyst composition while substantially normalizing the entiomeric...
2018/0186910 A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS
The disclosure provides a polymerization process for producing ethylene based polymers comprising polymerizing ethylene and optionally one or more a-olefins in...
2018/0186909 FLASHLINE HEATER SYSTEM AND METHOD
The present embodiments provide a system and method for separation within a polymer production process. Specifically, a flashline heater configured according...
2018/0186908 Methods of Preparing a Catalyst
A method of preparing a catalyst support comprising contacting an acid-soluble titanium-containing compound with an acid to form a first mixture; contacting...
2018/0186907 DEVELOPER, PATTERN FORMING METHOD, AND ELECTRONIC DEVICE MANUFACTURING METHOD
Provided is a pattern forming method including the successive steps of: a resist film forming step of forming a resist film using an actinic ray-sensitive or...
2018/0186906 PROCESS FOR TRANSITIONING BETWEEN INCOMPATIBLE CATALYSTS
The invention relates to a process for transitioning from a first continuous polymerization reaction in a gas phase reactor conducted in the presence of a...
2018/0186905 METHODS FOR CHLORINATING POLYVINYL CHLORIDE
A method for chlorinating polyvinyl chloride, the method comprising providing polyvinyl chloride particles having a chlorination accelerant associated...
2018/0186904 HYDROCARBON RESIN, METHOD FOR PREPARING HYDROCARBON RESIN, AND ADHESIVE COMPOSITION
This invention relates to a hydrogenated hydrocarbon resin and a method of preparing the same, wherein the preparation process is simplified, material supply...
2018/0186903 HYDROGENATED PETROLEUM RESIN, AND PRODUCTION METHOD AND USE THEREFOR
The present invention relates to a hydrogenated petroleum resin, and to a manufacturing method and use thereof. More specifically, it relates to a hydrogenated...
2018/0186902 CATALYSTS
The present invention relates to polymerisation catalysts.
2018/0186901 METHOD FOR PRODUCING CROSSLINKED HYALURONIC ACID
The present invention relates to the field of hyaluronic acid-based gel compositions suitable for use as soft tissue fillers, and more specifically to a novel...
2018/0186900 Novel Hyaluronic Acid-Based Hydrogels Having Medical Applications
Provided herein are novel hyaluronic acid-based materials for in-situ gelation in wounds and other contexts, which materials are biocompatible and which have...
2018/0186899 COMPOSITIONS OF PARTIALLY DEACETYLATED CHITIN DERIVATIVES
The present invention relates to compositions comprising biologically active chitinous oligomers and their endotoxin purified and partially deacetylated chitin...
2018/0186898 Bispecific Antibodies that Neutralize TNF-alpha and IL-6: Novel Therapeutic Agents for Autoimmune Disease
The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one anti-TNF-.alpha. antibody or antigen-binding...
2018/0186897 NOVEL VACCINES IN PREVENTION AND TREATMENT OF MALARIA
The present invention provides a pharmaceutical composition, for example a vaccine, which comprises a RIFIN, which is able to bind to a mutated LAIR-1...
2018/0186896 VACCINES FOR THE TREATMENT AND PREVENTION OF IGE MEDIATED DISEASES
Disclosed is a vaccine for use in the prevention or treatment of an Immunoglobulin E (IgE-) related disease, comprising a peptide bound to a pharmaceutically...
2018/0186895 ANTIBODIES TARGETING B-CELL RECEPTOR COMPLEX MEMBRANE BOUND IGM AND USES THEREOF
The present invention relates to antibodies targeting the membrane bound IgM (mIgM) of the B-cell receptor complex found in B-cell lymphomas and leukemias and...
2018/0186894 TARGETED MODIFIED IL-1 FAMILY MEMBERS
The present disclosure relates to a modified Interleukin-1 (IL-1) family member cytokine, with reduced activity via its cytokine receptor, wherein said...
2018/0186893 CARBONIC ANHYDRASE IX-SPECIFIC ANTIBODIES AND USES THEREOF
The present invention relates to isolated or purified antibodies or fragments thereof specific for Carbohydrate Anhydrase IX (CA-IX) and their use as...
2018/0186892 MONOCLONAL ANTIBODIES BINDING MCM5
The present invention relates to antibodies that bind to Mcm5. The invention further relates to compositions or kits comprising the antibodies, hybridomas...
2018/0186891 ANTI-FIBROBLAST ACTIVATION PROTEIN (FAP) ANTIBODIES FOR TREATMENT AND DIAGNOSIS
The present invention relates to the diagnosis and treatment of diseases, such as cancer and inflammatory disorders. The invention provides, and involves the...
2018/0186890 ANTI-CD276 ANTIBODIES (B7H3)
Polypeptides and proteins that specifically bind to and immunologically recognize CD276 are disclosed. Chimeric N antigen receptors (CARs), anti-CD276 binding...
2018/0186889 ANTI-CD40 ANTIBODIES AND THEIR USES
The present disclosure provides novel anti-CD40 antibodies, compositions including the new antibodies, nucleic acids encoding the antibodies, and methods of...
2018/0186888 ANTIBODIES THAT BIND TO TL1A AND METHODS OF TREATING INFLAMMATORY OR AUTOIMMUNE DISEASE COMPRISING...
Methods and compositions for treating inflammatory or autoimmune diseases in a subject comprising blocking the interaction between DR3 and TL1A. In the methods...
2018/0186887 THERAPEUTIC AGENT FOR MENTAL ILLNESS COMPRISING IL-6 INHIBITOR AS ACTIVE INGREDIENT
The present invention provides a novel therapeutic agent for mental illness. The therapeutic agent for mental illness comprises an IL-6 inhibitor as an active...
2018/0186886 Anti-Neuropilin Antigen-Binding Proteins and Methods of Use Thereof
Provided herein are antigen-binding proteins (ABPs) that selectively bind to NRP-1 and its isoforms and homologs, and compositions comprising the ABPs. Also...
2018/0186885 FZD7 SPECIFIC ANTIBODIES AND VACCINES TO TREAT CANCER AND CONTROL STEM CELL FUNCTION
The present invention is directed to antibodies and fragments thereof having binding specificity for FZD7, which preferably do not substantially interact with...
2018/0186884 ANTI-VEGFR ANTIBODY AND USES THEREOF
The present invention relates to an antibody or antigen-binding fragment thereof that bind human vascular endothelial growth factor receptor 2 (VEGFR-2). The...
2018/0186883 HUMAN ANTIBODIES TO PD-L1
The present invention provides antibodies that bind to the T-cell co-inhibitor ligand programmed death-ligand1 (PD-L1) protein, and methods of use. In various...
2018/0186882 ANTIBODY MOLECULES TO PD-L1 AND USES THEREOF
Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The...
2018/0186881 ANTI-HUMAN TIM-3 ANTIBODIES AND METHODS OF USE THEREOF
An anti-human T-cell immunoglobulin domain and mucin domain 3 (TIM-3) antibody, can bind the peptides, comprising the amino-acid sequence RKGDVSL (SEQ ID NO:...
2018/0186880 NATIVE HUMAN ANTIBODIES FOR IMMUNE CHECKPOINT MODULATION TARGETS TIM-3 AND B7-H3
Novel monoclonal antibodies directed against immune checkpoint modulator (ICM) proteins TIM-3 and B7-H3 are useful in treating cancer and immune system disorders.
2018/0186879 EMBIGIN INHIBITION FOR PROMOTION OF HEMATOPOIETIC STEM AND PROGENITOR CELL EXPANSION
Disclosed herein are methods for enhancing hematopoietic reconstitution of a subject. One method involves administering a therapeutically effective amount of...
2018/0186878 CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
The present disclosure is related to compositions that include polynucleotides encoding chimeric receptors, methods of delivering polynucleotides encoding...
2018/0186877 METHOD FOR SUPPRESSING BLOOD COAGULATION REACTION FOR WHICH LOX-1 IS RESPONSIBLE
The present invention provides an anti-blood coagulant capable of selectively suppressing a pathological blood coagulation reaction without increasing the risk...
2018/0186876 ANTI CD37 ANTIBODIES
Chimeric and humanized anti-CD37 antibodies and pharmaceutical compositions containing them are useful for the treatment of B cell malignancies and autoimmune...
2018/0186875 ANTI-TIGIT ANTIBODIES AND METHODS OF USE
The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
2018/0186874 ANTIBODIES TO IL-6 AND USE THEREOF
The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for IL-6. Another embodiment of...
2018/0186873 Anti-IL-5 Antibodies
Disclosed herein are fully human antibody molecules that immunospecifically bind to human IL-5. The antibody molecules can bind to human IL-5 with an...
2018/0186872 IL-11RA ANTIBODIES
IL-11Ra antibodies are disclosed. Also disclosed are compositions comprising the IL-11Ra antibodies, and methods using the IL-11Ra antibodies.
2018/0186871 IL-11 ANTIBODIES
IL-11 antibodies are disclosed. Also disclosed are compositions comprising the IL-11 antibodies, and methods using the IL-11 antibodies.
2018/0186870 Antibodies against phosphorylcholine in combination therapy with biologic agents
Antibodies against PC, PC conjugate or bioactive components and/or fragments thereof for use in combination therapy with one or more biologic agents and/or...
2018/0186869 High Affinity Human Antibodies to Human Angiopoietin-2
The present invention provides antibodies that bind to angiopoietin-2 (Ang-2) and methods of using same. According to certain embodiments of the invention, the...
2018/0186868 ANTIBODY AGAINST HUMAN NRG1 PROTEIN
An object is to provide an antibody capable of specifically recognizing a human NRG1 protein isoform, and suppressing signal transduction in which the isoform...
2018/0186867 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive...
2018/0186866 AFFINITY CHROMATOGRAPHY PURIFICATION WITH LOW CONDUCTIVITY WASH BUFFER
Herein is reported a method for producing a bispecific antibody comprising a first antigen-binding site that specifically binds to a first antigen and a second...
2018/0186865 Method for the reduction of host cell proteins in affinity chromatography
Herein is reported a method for producing a human IgG4 or IgG1 isotype antibody comprising the following steps a) cultivating a cell comprising a nucleic...
2018/0186864 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES
A method for treating or preventing laminitis is provided comprising administering to an ungulate a therapeutically or prophylactically effective amount of a...
2018/0186863 MODIFIED ANTIBODY REGIONS AND USES THEREOF
The present invention relates to modified Fc regions of antibodies, and uses thereof, such as in antibodies that contain an Fc region of the present invention.
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