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Patent # Description
2018/0185396 SYNTHETIC COMPOSITION FOR MICROBIOTA MODULATION
A human milk oligosaccharide (HMO) or a synthetic composition comprising said HMO, for use in increasing the abundance, particularly the relative abundance, of...
2018/0185395 ANTICANCER AGENT
The present invention aims to provide a therapeutic drug for cancer having a superior treatment effect. A cancer treatment using a CBP/catenin inhibitor and an...
2018/0185394 PHARMACEUTICAL TETRACYCLINE COMPOSITION FOR DERMATOLOGICAL USE
Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises...
2018/0185393 PHARMACEUTICAL COMPOSITION CONTAINING CELECOXIB
Disclosed herein is a pharmaceutical composition comprising pharmaceutical formulation of complexed Celecoxib and crystalline Celecoxib to provide fast and...
2018/0185392 Pharmaceutical Compositions and Methods
This invention relates the use of cortisol blockers (e.g., glucocorticoid receptor [GR] antagonists) for the treating or preventing viral infections, treating...
2018/0185390 FORMULATION AND PROCESS FOR LIMITING NERVE TRAUMA
Disclosed in some forms is a process of limiting the impact of surgery on a nerve, the process comprising applying a therapeutic substance to the nerve during...
2018/0185389 APPLICATIONS FOR LEVONORGESTREL IN PREPARING ANTI-OVARIAN CANCER PRODUCTS
This invention discloses uses for levonorgestrel in preparing anti-ovarian cancer products. This invention provides uses for levonorgestrel in the preparation...
2018/0185388 APPLICATIONS FOR ETONOGESTREL IN PREPARING ANTI-PROSTATE CANCER PRODUCTS
This invention discloses uses for etonogestrel in preparing anti-prostate cancer products. This invention provides uses for etonogestrel in preparing...
2018/0185387 APPLICATIONS OF DESOGESTREL IN THE PREPARATION OF ANTI-COLON CANCER/BREAST CANCER ER-NEGATIVE AH...
This invention discloses applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products. This...
2018/0185386 APPLICATIONS FOR ESTRADIOL IN PREPARING ANTI-SMALL CELL LUNG CANCER AND/OR OVARIAN CANCER AND/OR OSTEOSARCOMA...
This invention discloses uses for estradiol in preparing anti-small cell lung cancer and/or ovarian cancer and/or osteosarcoma products. This invention...
2018/0185385 PRESERVATIVE FREE BIMATOPROST AND TIMOLOL SOLUTIONS
The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intraocular pressure and treatment of glaucoma.
2018/0185384 DRUG THERAPY FOR PREVENTING OR TREATING GLAUCOMA
There is provided a drug therapy for prevention of glaucoma or prevention or treatment of ocular hypertension, with a potent ocular hypotensive effect and...
2018/0185383 IMIDAZODIAZEPINE COMPOUND
[Problem] Provided is a compound which is useful as a dopamine D1 receptor positive allosteric modulator (D1 PAM). [Means for Solution] The present inventors...
2018/0185382 COMPOSITIONS AND METHODS FOR TREATING CANCER
A method of treating cancer in a subject in need thereof includes administering to the subject therapeutically effective amounts of a PP2A activator and a...
2018/0185381 METHOD OF TREATING MEDULLOBLASTOMA
A method of treating a medulloblastoma in a mammal is provided comprising administering to the mammal a compound having the following general formula (1):...
2018/0185380 MELOXICAM FOR THE TREATMENT OF RESPIRATORY DISEASES IN PIGS
A method of treating or preventing a respiratory disease in a pig is described that includes administering to the pig in need thereof an effective amount of...
2018/0185379 APPLICATIONS FOR PROMETHAZINE IN PREPARING ANTI-LIVER CANCER AND/OR COLON CANCER AND/OR LUNG CANCER PRODUCTS
This invention provides uses for promethazine in the preparation of products to treat liver cancer and/or colon cancer and/or lung cancer. From carrying out...
2018/0185378 ANTIMICROBIAL DELIVERY SYSTEM FOR THE PREVENTION AND TREATMENT OF INFECTIONS IN THE COLON
This invention relates to the prophylactic and/or therapeutic application of antimicrobials that are, for example, administered orally as a delayed release...
2018/0185377 METHODS FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS
The present invention discloses compounds according to Formula (I): or a pharmaceutically acceptable salt thereof, or a solvate or the salt of a solvate...
2018/0185376 Thiazideamide Derivative and Use Thereof
The invention belongs to the technical field of medicines. In particular, the invention relates to a thiazideamide derivative compound or a pharmaceutically...
2018/0185375 COMPOSITIONS AND METHODS FOR THE TREATMENT OF SUBSTANCE USE DISORDERS, ADDICTION, AND PSYCHIATRIC DISORDERS
The present invention features a composition comprising a first agent and a second agent for treating disorder associated with aberrant activity in the HPA...
2018/0185374 INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS
The present invention provides methods and compositions for treating or preventing viral infections using modulators of host cell enzymes relating to mTOR. The...
2018/0185373 METHODS AND COMPOSITIONS FOR TREATING THYROID-RELATED MEDICAL CONDITIONS WITH REDUCED FOLATES
The present invention provides methods and compositions for treating thyroid-related medical conditions. Many thyroid-related medical conditions exist that go...
2018/0185372 USE OF TREM-1 INHIBITORS FOR TREATMENT, ELIMINATION AND ERADICATION OF HIV-1 INFECTION
Compounds, compositions, and methods of treatment and prevention of HIV, including HIV-1 and HIV-2, Dengue, and Chikungunya infection are disclosed. The...
2018/0185371 SYSTEMS AND METHODS FOR TREATING CANCER
Embodiments of the invention provide a method of treating cancer, the method comprising providing a subject having cancer cells, and contacting the cancer...
2018/0185370 PYRAZINOQUINAZOLINONE DERIVATIVES WITH ANTIBACTERIAL ACTIVITY, METHODS AND USES THEREOF
The present disclosure relates to compounds and compositions displaying antibacterial activity, particularly against Gram-positive bacteria. The compounds...
2018/0185369 HYDROXYACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
Compounds of formula (I): ##STR00001## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.14, A and n are as defined in the...
2018/0185368 SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
The invention provides substituted pyrrolo[1,2-a]pyrimidines and related organic compounds, compositions containing such compounds, medical kits, and methods...
2018/0185367 N-SUBSTITUTED HYDROXAMIC ACIDS WITH CARBON-BASED LEAVING GROUPS AS EFFICIENT HNO DONORS AND USES THEREOF
N-substituted hydroxamic acids with carbon-based leaving groups as efficient HNO donors are disclosed. Pharmaceutical compositions and kits comprising such...
2018/0185366 Inhibitors of Multidrug Resistance Transporter P-Glycoprotein
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug...
2018/0185365 Pharmaceutical Combinations
A pharmaceutical combination comprising (a) an ALK inhibitor, or a pharmaceutically acceptable salt thereof, and (b) at least one HDMA-2/p53 receptor inhibitor...
2018/0185364 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
The present invention features a compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, where R.sub.1, R.sub.2, R.sub.3, W, X, Y, Z,...
2018/0185363 PHTHALAZINONE DERIVATIVES
Compounds of the formula (I): ##STR00001## wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NR.sup.X or...
2018/0185362 METALLOENZYME INHIBITOR COMPOUNDS
Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
2018/0185361 METHODS FOR TREATING CANCER USING DIHYDROPYRAZINO-PYRAZINE COMPOUND COMBINATION THERAPY
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound and an...
2018/0185360 CGRP RECEPTOR ANTAGONIST COMPOUNDS FOR TOPICAL TREATMENT OF SKIN DISORDERS
The use of a CGRP receptor antagonist compound of formula (I) for topical application is described for treating and/or preventing skin inflammatory pathologies...
2018/0185359 STABLE PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
Provided is a stable pharmaceutical composition for oral administration comprising 6-ethyl-3-({3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}- ...
2018/0185358 METHODS FOR PRODUCING ARIPIPRAZOLE SUSPENSION AND FREEZE-DRIED FORMULATION
Disclosed are a method for producing an aripiprazole suspension, wherein the aripiprazole has a mean particle size of 1 to 10 ?m, the method comprising the...
2018/0185357 USE OF LEVOCETIRIZINE AND MONTELUKAST IN THE TREATMENT OF TRAUMATIC INJURY
The embodiments described herein include methods and formulations for treating lung and brain injury. The methods and formulations include, but are not limited...
2018/0185356 LOW DOSE PRODUCT AND METHOD FOR TREATING DIARRHEA
A method of treating diarrhea in a patient includes administering a dose of 2.0-7.0 mg of cetirizine and 3.0-15.0 mg of famotidine.
2018/0185355 Method of Treating Dyskinesia
Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action .mu.-opioid receptor antagonist/- -opioid...
2018/0185354 IMMEDIATE RELEASE ABUSE-DETERRENT GRANULATED DOSAGE FORMS
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse...
2018/0185353 ABUSE-RESISTANT CONTROLLED-RELEASE OPIOID DOSAGE FORM
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
2018/0185352 ABUSE DETERRENT PHARMACEUTICAL COMPOSITIONS
Abuse deterrent pharmaceutical compositions, processes for their preparation and methods of use thereof are described. An exemplary composition is a solid oral...
2018/0185351 THERAPY OF SMALL-CELL LUNG CANCER (SCLC) WITH A TOPOISOMERASE-I INHIBITING ANTIBODY-DRUG CONJUGATE (ADC)...
The present invention relates to treatment of SCLC with therapeutic ADCs comprising a drug attached to an anti-Trop-2 antibody or antigen-binding antibody...
2018/0185350 RESIQUIMOD TOPICAL AND INJECTABLE COMPOSITIONS FOR THE TREATMENT OF NEOPLASTIC SKIN CONDITIONS
Compositions and methods for treatment of viral skin disease, precancerous and cancerous skin disease, and other neoplasms are disclosed.
2018/0185349 USE OF HSP70 AS A REGULATOR OF ENZYMATIC ACTIVITY
The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the...
2018/0185348 IMMUNOTHERAPEUTIC DOSING REGIMENS COMPRISING POMALIDOMIDE AND AN ANTI-CS1 ANTIBODY FOR TREATING CANCER
The invention described herein relates to therapeutic dosing regimens and combinations thereof for use in enhancing the therapeutic efficacy of anti-CS1...
2018/0185347 TETRAHYDROCYCLOPENTA[B]INDOLE COMPOUNDS AND PHOSPHODIESTERASE INHIBITORS FOR THE TREATMENT OF THE SIGNS AND...
Methods of treating the signs and symptoms of Benign Prostatic Hyperplasia (BPH) in a subject by administering at least one tetrahydrocyclopenta[b]indole...
2018/0185346 APPLICATIONS FOR NICARDIPINE IN PREPARING ANTI-LUNG CANCER PRODUCTS
This invention discloses uses for nicardipine in preparing anti-lung cancer products. This invention provides uses for nicardipine in the preparation of...
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