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Patent # Description
2019/0062480 CURABLE-RESIN COMPOSITION AND CURED OBJECT THEREOF
Disclosed is a curable resin composition that includes radical polymerizable monomers including a first monofunctional radical polymerizable monomer and a...
2019/0062479 POLYMER PARTICLES
Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.
2019/0062478 PROCESS FOR OBTAINING A CATIONIC POLYMER WITH AN AT LEAST BIMODAL MOLECULAR WEIGHT DISTRIBUTION
A process for obtaining a cationic polymer is disclosed. The cationic polymer is obtained by polymerization of at least one cationic monomer, at least one...
2019/0062477 CURABLE COMPOSITION
The present invention relates to a curable composition which can be cured by radiation and/or the influence of temperature; a cured product which is obtained...
2019/0062476 Use of a Vinylidene Fluoride Copolymer for Providing a Film with Properties of Adhesion
The present invention relates to the use of a fluorinated copolymer in the manufacture of a solid polymer film, to give said film properties of adhesion to a...
2019/0062475 POLYOLEFIN PRODUCTION WITH CHROMIUM-BASED CATALYSTS
A system and method for feeding a chromium-based catalyst to a polymerization reactor; adding a reducing agent to the chromium-based catalyst, and polymerizing...
2019/0062474 SUPPORTED HYBRID METALLOCENE CATALYST, AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME
The present disclosure relates to a supported hybrid metallocene catalyst and a method for preparing a polyolefin using the same. When the supported hybrid...
2019/0062473 POLAR GROUP-CONTAINING OLEFIN COPOLYMER, MULTINARY POLAR OLEFIN COPOLYMER, OLEFIN RESIN COMPOSITION, AND...
The present invention relates to a polar group-containing olefin copolymer (A') which is produced through polymerization using a transition metal catalyst,...
2019/0062472 PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS
The present invention relates to a process for preparing high-reactivity isobutene homo- or copolymers with a content of terminal vinylidene double bonds per...
2019/0062471 Ziegler-Natta Catalyzed Polyisoprene Articles
A polymeric article comprises an elastomeric layer comprising cured synthetic polyisoprene particles that comprise a Ziegler-Natta catalyzed polyisoprene.
2019/0062469 Polymer-Encased Nanodiscs With Improved Buffer Compatibility
The present invention includes compositions, methods, and methods of making and using a polymer-encased nanodisc comprising: one or more integral membrane...
2019/0062468 POLYMERIC ACID CATALYSTS AND USES THEREOF
Polymers useful as catalysts in non-enzymatic saccharification processes are provided. Provided are also methods for hydrolyzing cellulosic materials into...
2019/0062467 POLYMERIZATION OF MICHAEL-TYPE MONOMERS
Catalyst and initiator compounds for precision polymerization of Michael-type monomers, precatalytic bridged complexes, such as those having formula...
2019/0062466 METHOD FOR PRODUCING POLYOLEFIN AND POLYOLEFIN PRODUCTION SYSTEM
A polyolefin production system is provided. The polyolefin production system includes a plurality of gas-phase polymerization tanks configured to polymerize an...
2019/0062465 METHOD FOR PRODUCING POLYOLEFIN AND POLYOLEFIN PRODUCTION SYSTEM
A polyolefin production system is provided. The polyolefin production system includes a plurality of gas-phase polymerization tanks configured to polymerize an...
2019/0062464 POLYMER PRODUCTION METHOD
A polymer production method whereby: a flow reactor comprising a flow path wherein a plurality of liquids can be mixed is used; and a monomer is anionically...
2019/0062463 METHOD FOR PRODUCING POLYOLEFIN
A method for producing a polyolefin is provided. The method includes steps of polymerizing an olefin in a first gas-phase polymerization tank to obtain...
2019/0062462 CATECHOL GROUP MODIFIED BIOMACROMOLECULAR SCAFFOLD MATERIAL AND PREPARATION METHOD THEREOF
The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing...
2019/0062461 PROCESS FOR PREPARING A CROSS-LINKED HYALURONIC ACID PRODUCT
Efficient cross-linking of hyaluronic acid (HA) is provided by a manufacturing process. In the process, HA is activated by an initial cross-linking in an...
2019/0062460 POLYMORPHS OF SUGAMMADEX AND PROCESS FOR PREPARATION OF SUGAMMADEX
The present invention provides a crystalline form of Suagmmadex sodium, characterized by an X-ray powder diffraction pattern. The present invention further...
2019/0062459 METHOD FOR PREPARATION OF SUGAMMADEX SODIUM
The present invention provides a method for improved preparation of Sugammadex sodium.
2019/0062458 POROUS POLYMERIC CELLULOSE PREPARED VIA CELLULOSE CROSSLINKING
The invention relates to porous polymeric cellulose prepared via cellulose crosslinking. The porous polymeric cellulose can be incorporated into membranes...
2019/0062457 METHODS AND COMPOSITIONS RELATING TO ANTI-CHI3L1 ANTIBODY REAGENTS
It is demonstrated herein that inhibitors of immune checkpoints and CHI3L1 are synergistic. Accordingly, described herein are methods and compositions relating...
2019/0062456 ANTIBODIES AGAINST CD73 AND USES THEREOF
The present invention provides isolated monoclonal antibodies, particularly human antibodies, that bind to human Cluster of Differentiation 73 (CD73) with high...
2019/0062455 HIGHLY CONCENTRATED LOW VISCOSITY MASP-2 INHIBITORY ANTIBODY FORMULATIONS, KITS, AND METHODS OF TREATING...
The present invention relates to therapeutic methods of using stable, high-concentration low-viscosity formulations of MASP-2 inhibitory antibodies, and kits...
2019/0062454 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements...
2019/0062453 BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE
The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site...
2019/0062452 Methods and Compositions for the Treatment of Immunomodulatory Diseases and Disorders
Compositions and methods for the treatment of an autoantibody disease or disorder are disclosed.
2019/0062451 PCSK9 ANTIBODY PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY...
Embodiments provide swallowable devices, preparations and methods for delivering therapeutic agents (TAs) within the GI tract such as antibodies...
2019/0062450 ENGINEERED ANTIGEN PRESENTING CELLS AND USES THEREOF
The present invention relates to engineered extra-cellular vesicle internalizing receptors that have the ability to enhance uptake, processing, and...
2019/0062449 USE OF ANTI-DKK-1 MONOCLONAL ANTIBODIES FOR TREATMENT OF LIVER CANCER
The invention provides a method of treating liver cancer comprising administering anti-DKK1 monoclonal antibody to a subject in need thereof. Anti-DKK1...
2019/0062448 ANTI-CD39 ANTIBODIES, COMPOSITIONS COMPRISING ANTI-CD39 ANTIBODIES AND METHODS OF USING ANTI-CD39 ANTIBODIES
Provided herein are antibodies that selectively bind to CD39 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are...
2019/0062447 TREATMENT OF DIABETES MELLITUS
The present invention provides a method of treating insulin-dependent diabetes mellitus in a subject, comprising administering to the subject a therapeutically...
2019/0062446 Anti-GITR Antibodies and Methods of Use Thereof
The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions...
2019/0062445 FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one...
2019/0062444 COMBINATION THERAPY COMPRISING ANTI-ANGIOGENESIS AGENTS AND OX40 BINDING AGONISTS
The invention provides compositions and methods for treating cancers. The method comprises administering an anti-angiogenesis agent and an OX40 binding agonist.
2019/0062443 HIGHLY POTENT ANTIBODIES BINDING TO DEATH RECEPTOR 4 AND DEATH RECEPTOR 5
The present invention is directed toward monoclonal antibodies that bind to death receptor 4 and/or death receptor 5, a pharmaceutical composition comprising...
2019/0062442 ANTI-PrP ANTIBODIES AND USES THEREOF
The present disclosure provides antibodies and antigen-binding fragments capable of binding PrP.sup.c. The disclosure further provides methods for making and...
2019/0062441 Methods For Treating Rare Genetic Disorders Using Glucagon Receptor Antagonistic Antibodies
The present disclosure relates to methods for treating various rare genetic disorders which are characterized, in part, by abnormal resistance to insulin...
2019/0062440 Antigen Binding Proteins that Bind CCR2
There is disclosed compositions and methods relating to or derived from anti-CCR2 antibodies. More specifically, there is disclosed fully human antibodies that...
2019/0062439 ST2L ANTAGONISTS AND METHODS OF USE
The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
2019/0062438 CD131 BINDING PROTEINS AND USES THEREOF
The present disclosure provides a CD131-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain binds to or...
2019/0062437 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also...
2019/0062436 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also...
2019/0062435 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also...
2019/0062434 BIVALENT BISPECIFIC ANTIBODY HYBRID PROTEIN EXPRESSION AND PREPARATION METHODS
The present disclosure relates to the field of biological technologies, and discloses a method for expressing and preparing a bivalent bispecific antibody. In...
2019/0062433 ANTI-SORTILIN ANTIBODIES AND METHODS OF USE THEREOF
The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments,...
2019/0062432 ANTI-B7-H4 ANTIBODIES AND IMMUNOCONJUGATES
The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
2019/0062431 Immunological Reagents
This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or...
2019/0062430 FLAG TAGGED CD19-CAR-T CELLS
The present invention provides chimeric antigen receptor (CAR)-T cells modified to express a CAR fusion protein comprising from N-terminus to C-terminus: (i) a...
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