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Patent # Description
2019/0070343 Methods, Systems, And Devices For Joint To Pump Elevation Level User Interfaces, Autocalibration For Joint...
Various exemplary methods, systems, and devices for joint to pump elevation level user interfaces, autocalibration for joint elevation, and joint pressure...
2019/0070342 FREE-STANDING BIODEGRADABLE PATCH
Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially nasal applications are provided, wherein the patch...
2019/0070341 Coating Formulations for Scoring or Cutting Balloon Catheters
The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive...
2019/0070340 A DEVICE FOR REPAIR SURGERY OF CYLINDRICAL ORGANS, PARTICULARLY RUPTURED TENDONS, COMPRISING A THERAPEUTIC...
A device for repair surgery of cylindrical organs, particularly of ruptured tendons, is configured as a tubular sheath (T) made of a mesh of elastic fibers...
2019/0070339 ELECTRO-MECHANICALLY STRETCHED MICRO FIBERS AND METHODS OF USE THEREOF
The presently disclosed subject matter provides a scalable and electrostretching approach for generating hydrogel microfibers exhibiting uniaxial alignment...
2019/0070338 Gelatin/Elastin Composites for Peripheral Nerve Repair
Neurosupportive materials that possess strong tissue adhesion were synthesized by photocrosslinking two polymers, gelatin methacryloyl (GelMA) and...
2019/0070337 MULTILAYERED CELL SHEET OF NEURAL CREST STEM CELLS AND METHOD OF PREPARING THE SAME
A method of manufacturing a multilayered cell sheet of neural crest stem cells (NCSCs), includes: (1) isolating and culturing NCSCs from peripheral nerves; (2)...
2019/0070336 METHOD FOR PRODUCING EXTRACELLULAR MATRIX MEMBRANE DERIVED FROM BIOCOMPATIBLE PORCINE CARTILAGE CAPABLE OF...
The present invention relates to a method for preparing a biocompatible porcine cartilage-derived extracellular matrix membrane capable of adjusting an in-vovo...
2019/0070335 AMINION BASED CONDUIT TISSUES
Described herein is the method of preparation for amnion-based tissue conduits. Amnion based tissue conduits are obtained from placental and umbilical cord...
2019/0070334 LUMINAL PROSTHESES AND METHODS FOR COATING THEREOF
Luminal prostheses comprise scaffolds having coatings adhered to at least a portion of their outer surfaces. The surfaces are modified to enhance binding of...
2019/0070333 SOLID FORMS FOR TISSUE REPAIR
This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage...
2019/0070332 OILY COMPOSITIONS
The present invention provides emulsion compositions comprising an continuous oil phase, a discontinuous aqueous phase and a plurality of microparticles. The...
2019/0070331 SYSTEM FOR TREATING EMISSIONS FROM A VEHICLE
A system for treating emissions from a vehicle includes an ozone generator, a first holding tank, and an exhaust vent. The first holding tank is downstream...
2019/0070330 Treated Membrane for Fragrance Delivery
A treated vapor permeable microporous membrane includes: a microporous membrane having a first side and a second side opposite the first side. The membrane...
2019/0070329 VOLATILE COMPOSITION DISPENSER HAVING AN AIR PUMP AND A METHOD OF DELIVERING A VOLATILE COMPOSITION TO AN...
A volatile composition dispenser and a method of dispensing a volatile composition is provided. The volatile composition dispenser includes a reservoir for...
2019/0070328 Scent Dispenser with Illuminating Arrangement
A scent dispenser includes a main body, a liquid tank unit, a diffusing member for diffusing the liquid from the main body, a control module supported in the...
2019/0070327 AIR FRESHENER GEL CONTAINING CELLULOSE, HEMICELLULOSE, LIGNIN
The present invention relates to the field of air freshener. It relates more particularly to a gel composition which allows for an effective and prolonged...
2019/0070326 Oral Care Implement Sterilization System
An oral care sterilization system in one embodiment includes an oral care implement and sterilization unit. The oral care implement may be a toothbrush...
2019/0070325 APPARATUS AND SYSTEM FOR STERILIZATION OF GARMENTS USING ULTRAVIOLET LIGHT
An ultraviolet (UV) sterilization system and a device for sterilizing a garment having shoulder, torso, and sleeve portions including a garment enclosure; a...
2019/0070324 DATA COLLECTION DEVICE WITH ANTI-MICROBIAL ILLUMINATION
A code reader may include a housing configured to be adjustably oriented. The housing may include at least one orientation corresponding with a cleaning...
2019/0070323 INACTIVATION OF PATHOGENS IN EX VIVO BLOOD PRODUCTS IN STORAGE BAGS USING VISIBLE LIGHT
Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma...
2019/0070322 Treatment of Proliferative Disorders Using Antibodies to PSMA
Methods of treating cancer in a patient are provided. In some embodiments the method comprises administering an antibody that is capable of binding to the...
2019/0070321 SMALL MOLECULES FOR DUAL FUNCTION POSITRON EMISSION TOMOGRAPHY (PET) AND CELL SUICIDE SWITCHES
The present invention includes an engineered cell comprising a chimeric antigen receptor (CAR) further comprising a nucleic acid molecule comprising a suicide...
2019/0070319 SILICONE-BASED ENTERIC CT CONTRAST MATERIAL
The present invention provides a silicon-based polymer contrast media for use in CT imaging. In an exemplary embodiment, the invention provides an enteric...
2019/0070318 A REPORTER PLATFORM FOR REAL TIME MONITORING OF DRUG EFFICACY
Described herein is a reporter material platform that can be used to directly monitor the drug response in real-time. The reporter material can include an...
2019/0070317 IN-VIVO REACTIVE SPECIES IMAGING
The disclosure features methods that include: administering to a subject a composition that includes particles, where each one of the particles features at...
2019/0070316 Non-invasive in vivo imaging and methods for treating diabetes
The present invention provides novel drug discovery platforms and methods for treating diabetes.
2019/0070315 LOCALIZED IMMUNOSUPPRESSION VIA OPTOGENETICALLY CONTROLLED CELLS
Embodiments described herein relate to suppressing the immune response locally within tissue transplants and certain conditions improperly affecting the immune...
2019/0070314 NANO/MICROMOTORS FOR ACTIVE AND DYNAMIC INTRACELLULAR PAYLOAD DELIVERY
Methods, systems, and devices are disclosed for intracellular payload delivery by nanomotor structures. In some aspects, a nanomotor for intracellular payload...
2019/0070313 TRI-MODAL NUCLEIC ACID DELIVERY SYSTEMS
Provided herein are nucleic acid delivery compositions, surfactants, kits comprising said materials, methods and uses thereof, and methods for the preparation...
2019/0070312 THYMIDINE KINASE
A polynucleotide comprising a nucleotide sequence encoding a thymidine kinase wherein at least one of the nucleotides corresponding to the splice donor site...
2019/0070311 GENE THERAPY FOR TREATING MUCOPOLYSACCHARIDOSIS TYPE II
A suspension useful for AAV9-mediated intrathecal and/or systemic delivery of an expression cassette containing a hIDS gene is provided herein. Also provided...
2019/0070310 NANOPARTICLE DRUG CONJUGATES
Described herein are nanoparticle drug conjugates (NDCs), which, in certain embodiments, comprise a non-toxic, multi-modality, clinically proven silica-based...
2019/0070309 HYDROGEL PRODRUG FOR TREATMENT
Aspects of the invention described herein include a hydrogel prodrug and methods of making a hydrogel prodrug for drug deliver}'. Also contemplated are methods...
2019/0070308 ANTIBODY-DRUG CONJUGATES AND USES THEREOF
The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may...
2019/0070307 RECOMBINANT HUMAN EPO-FC FUSION PROTEINS WITH PROLONGED HALF-LIFE AND ENHANCED ERYTHROPOIETIC ACTIVITY IN VIVO
A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has...
2019/0070306 OPTIMIZED TRANSGLUTAMINASE SITE-SPECIFIC ANTIBODY CONJUGATION
Provided herein are methods and compositions for site-specific conjugation of antibodies in the presence of a transglutaminase.
2019/0070305 BENZODIAZEPINES AND CONJUGATES THEREOF
Conjugates and compounds for making conjugates which are PBD molecules linked via the N10 position are disclosed, along with the use of the conjugates for...
2019/0070304 BIODEGRADABLE VECTORS FOR EFFICIENT RNA DELIVERY
The disclosure provides for vectors, and methods of using the vectors to efficiently deliver mRNA and/or ssRNA into cells.
2019/0070303 SULFOALKYL ETHER CYCLODEXTRIN COMPOSITIONS
SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an...
2019/0070302 NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS
Non-linear multiblock copolymer-drug conjugates for the treatment and prevention of diseases and disorders of the eye are provided. The polymer-drug conjugates...
2019/0070301 ACTIVATED POLYOXAZOLINES AND CONJUGATES AND COMPOSITIONS COMPRISING THE SAME
The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target...
2019/0070300 ZWITTERIONIC POLYMER BIOCONJUGATES AND RELATED METHODS
Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.
2019/0070299 DUAL-RATE RELEASE FORMULATION WITH HIGH DRUG LOADING
The present document describes a pharmaceutical excipient composition comprising a functionalized anionic polysaccharide having carboxyl groups complexed with...
2019/0070298 SUSTAINED-RELEASE DRUG CARRIER COMPOSITION
The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable...
2019/0070297 Management of Tractional Membranes
Methods and compositions are provided here to manage tractional membranes, as well as other diseases and disorders of the eye. Compositions comprising...
2019/0070296 SONODYNAMIC THERAPY
The present disclosure provides methods for treating diseased cells in a subject using sonodynamic therapy (SDT), comprising: administering to the subject a...
2019/0070295 Photoswitchable HDAC Inhibitors
This invention relates to photoswitchable inhibitors of histone deacetylases and methods of using the same.
2019/0070294 STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
2019/0070293 STABLE AQUEOUS FORMULATIONS OF ADALIMUMAB
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
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