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Patent # Description
2019/0071709 PROCESS AND SYSTEM FOR FLOW CYTOMETRY FLUORESCENT DETECTION OF REACTIVE MATERIALS IN VISCOUS NON-FILTERABLE...
A method of preparing a sample for cytometry detection of viable biological contaminants includes obtaining a non-aqueous sample, obtaining a suitable solvent,...
2019/0071708 COLLECTION BROTHS FOR MICROORGANISMS
A collection broth used for recovering microorganisms on a surface is provided. The collection broth includes a buffering system and a neutralization system....
2019/0071707 NMR METHODS AND SYSTEMS FOR THE RAPID DETECTION OF BACTERIA
The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
2019/0071706 COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING DISEASE
A method for increasing production of a polypeptide in a bacterial cell in culture is provided. The method can comprise contacting a bacterial cell in a...
2019/0071705 METHODS FOR MAKING HIGH INTENSITY SWEETENERS
Provided herein include methods of making mogroside compounds, e.g., Compound 1, compositions (for example host cells) for making the mogroside compounds, and...
2019/0071703 LOW GLYCEMIC SUGAR COMPOSITION
A composition includes a sugar source and inositol. The sugar source is one more sugars select from the group consisting of glucose, sucrose, sucrolose,...
2019/0071702 TRANSAMINASE BIOCATALYSTS
The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides.
2019/0071701 BENZYLISOQUINOLINE ALKALOIDS (BIA) PRODUCING MICROBES, AND METHODS OF MAKING AND USING THE SAME
Aspects of the invention include host cells that are engineered to produce benzylisoquinoline alkaloids (BIAs). The host cells include heterologous coding...
2019/0071700 METHOD FOR CULTURING MICROORGANISM, AND PROCESS FOR PRODUCING SUBSTANCE WITH MICROORGANISM
Using as a carbon source a long chain fatty acid which has not necessarily been efficaciously used in industry, culture of a microorganism and production of a...
2019/0071699 ENGINEERED CYANOBACTERIA WITH ENHANCED LIPID PRODUCTION
A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing sterol desaturase gene (SD) via...
2019/0071698 Method of Producing Lipid
A method of producing lipids, containing the steps of: culturing a transformant wherein the expressions of a gene encoding any one of the following proteins...
2019/0071697 IMPROVED PROPIONIBACTERIUM STRAINS FOR THE PRODUCTION OF PROPIONIC ACID
Disclosed herein are new strains of Propionibacterium and methods for the biosynthetic production of propionic acid.
2019/0071696 METHODS AND SYSTEMS FOR PROPAGATION OF A MICROORGANISM USING A PULP MILL AND/OR A PAPER MILL WASTE BY-PRODUCT,...
The present disclosure relates to using a source of one or more monosaccharides derived from a pulp or paper mill waste by-product for propagating...
2019/0071695 MICROFLUIDIC LASER-ACTIVATED INTRACELLULAR DELIVERY SYSTEMS AND METHODS
An intracellular delivery system and method are provided. The intracellular delivery system comprises a laser-activated surface and cells positioned at a...
2019/0071694 METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression...
2019/0071693 METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D (SP-D)
Some embodiments of the methods and compositions provided herein relate to the preparation surfactant protein-D (SP-D). Some embodiments include the expression...
2019/0071692 PROMOTER
The present invention relates to nucleic acid molecules which are capable of promoting transcription of operably-linked heterologous polynucleotides in...
2019/0071691 RECOMBINANT PROTEIN EXPRESSION USING A HYBRID CHEF1 PROMOTER
The invention provides expression vectors and host cells for high-level expression of recombinant proteins. The expression vectors comprise Chinese hamster...
2019/0071690 COMPOSITIONS AND METHODS FOR INSECTICIDAL CONTROL OF STINKBUGS
Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Pentatomidae plant pest, decrease the...
2019/0071689 MAIZE EVENT DP-033121-3 AND METHODS FOR DETECTION THEREOF
The disclosure provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the...
2019/0071688 COMPOSITIONS AND METHODS FOR MODIFYING GENOMES
Compositions and methods for modifying genomic DNA sequences are provided. The methods produce double-stranded breaks (DSBs) at pre-determined target sites in...
2019/0071687 A METHOD FOR INCREASING RESISTANT STARCH AND DIETARY FIBER IN RICE
The present invention discloses mutations in the genes encoding starch synthases and also in starch branching enzymes associated with enhanced dietary fibre...
2019/0071686 Means and Methods for Regulating Secondary Metabolite Production in Plants
This disclosure relates to the field of secondary metabolite production in plants. More specifically, the disclosure relates to chimeric genes and their use in...
2019/0071685 IDENTIFICATION OF CROP MYB TRANSCRIPTION FACTORS AND THEIR USE
Mutation of the rice ortholog of the Arabidopsis MTF1 gene results in increased rice transformation. CRISPR was used to generate several different mutations in...
2019/0071684 MUTANT XYLOSE-METABOLIZING ENZYME AND USE THEREOF
The present invention provides information on a mutant xylose isomerase gene and a mutant protein with which it is possible to impart high xylose metabolic...
2019/0071683 Solute Carrier Family 14 Member 1 (SLC14A1) Variants And Uses Thereof
The disclosure provides nucleic acid molecules, including cDNA, comprising an alteration that encodes variant human Solute Carrier Family 14 Member 1 (SLC14A1)...
2019/0071682 3'-UTR Sequences for Stabilization of RNA
The present invention relates to stabilization of RNA, in particular mRNA, and an increase in mRNA translation. The present invention particularly relates to a...
2019/0071681 AAV HEPARIN MUTANTS THAT DISPLAY SIGNIFICANTLY IMPROVED EYE AND BRAIN TRANSDUCTION
Disclosed are methods of gene delivery using capsid-modified recombinant adeno-associated viral (rAAV) particles. Exemplary methods are provided employing rAAV...
2019/0071680 MICROBIAL PRODUCTION OF NICOTINIC ACID RIBOSIDE
The present invention relates to a novel method, expression vectors, and host cells for producing nicotinic acid riboside by regulating the pathways that lead...
2019/0071679 ANTI-TUMOR THERAPY
Panels, compositions, and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders...
2019/0071678 MODULATION OF DYRK1B EXPRESSION
Provided herein are methods, compounds, and compositions for reducing expression of DYRKIB in an animal. Such methods, compounds, and compositions are useful...
2019/0071677 METHODS FOR TREATING HYPERCHOLESTEROLEMIA
Disclosed herein are antisense compounds and methods for decreasing LDL-C in an individual having elevated LDL-C. Additionally disclosed are antisense...
2019/0071676 RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS
RNA interference is provided for inhibition of HIF1A mRNA expression for treating patients with ocular angiogenesis, particularly for treating retinal edema,...
2019/0071675 INHIBITORS OF DEK PROTEIN AND RELATED METHODS
The present invention provides methods of treatment using inhibitors of DEK protein and DEK activity. Such methods include, but are not limited to, methods of...
2019/0071674 THERAPEUTIC STRATEGIES FOR OVARIAN CANCER: AMHR2-RNA APTAMER
Various aspects of the invention relate to aptamers that specifically bind Mullerian inhibitory substance II receptor (MISIIR).
2019/0071673 CRISPRs WITH IMPROVED SPECIFICITY
A composition for treating a lysogenic virus, including a vector encoding isolated nucleic acid encoding two or more gene editors chosen from gene editors that...
2019/0071672 Pharmaceutical Composition
The invention provides pharmaceutical compositions comprising short single stranded oligonucleotides, of length of between 8 and 17 nucleobases which are...
2019/0071671 THERAPEUTIC FOR TREATMENT OF DISEASES INCLUDING THE CENTRAL NERVOUS SYSTEM
The present disclosure provides filler or stuffer sequences, compositions thereof including expression cassettes and vectors, such as viral (e.g., AAV) vectors...
2019/0071670 Methods Of Treatment For Alpha-1 Antitrypsin Deficiency
The application relates to methods of treatment and treatment regimens for Alpha-1 Antitrypsin deficiency (AATD) and the conditions, manifestations, and...
2019/0071669 LIPID ENCAPSULATING INTERFERING RNA
The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule...
2019/0071668 COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF CANCER USING SLNCR ISOFORMS
The present invention relates to compositions and methods for identifying, assessing, preventing, and treating cancer and modulating immune responses using...
2019/0071667 SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow...
2019/0071666 MULTIPLEXED ANALYSIS OF NEURON PROJECTIONS BY SEQUENCING
The present invention provides a composition comprising a plurality of labeled neurons, each of which is labeled by an expression construct that encodes a...
2019/0071665 METHODS FOR CO-ISOLATION OF NUCELIC ACIDS AND PROTEINS
Provided are methods for isolating biomolecules, such as nucleic acids and proteins, from a sample using a silica-containing surface and/or a high salt, low pH...
2019/0071664 HYDROXYNITRILE LYASE
Provided are a method for obtaining an HNL gene and HNL derived from a millipede other than Chamberlinius hualienensis, and preparing a practically useable...
2019/0071663 ISOTACHOPHORESIS FOR PURIFICATION OF NUCLEIC ACIDS
The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be...
2019/0071662 Methods for the Isolation of Biomolecules and Uses Thereof
Methods for preparing and utilizing tunable electrostatic capture ("TEC") ligands that have an ionizable function are provided. The electrostatic nature of the...
2019/0071661 SYSTEMS, DEVICES, AND METHODS FOR ISOTACHOPHORESIS
The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be...
2019/0071660 CELL CULTURE MEDIUM FOR ADAMTS PROTEIN EXPRESSION
The present invention provides culture mediums that are useful for the expression of ADAMTS proteins, such as ADAMTS13. Methods for the expression and...
2019/0071659 COMPOSITIONS AND METHODS FOR PRODUCING CLOSTRIDIAL COLLAGENASES
The present invention provides a method for producing a drug product comprising a combination of highly purified collagenase I and collagenase II from...
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