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Patent # Description
2019/0083622 CANNABINOID FORMULATIONS AND METHODS INCLUDING THE ANTIOXIDANT C60
A cannabinoid formulation including a carbon-based antioxidant. Preferably, the formulation is a colloid including C60 and cannabinoids in a lipid-based...
2019/0083621 RS7 Antibodies
This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these...
2019/0083620 METHODS FOR INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDERGOING...
Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are...
2019/0083619 METHODS AND COMPOSITIONS FOR REMOVING, REDUCING, DISPERSING, DISRUPTING OR ERADICATING BIOFILMS AND DETERMINING...
Methods for removing, reducing, dispersing, disrupting or eradicating biofilms present on a surface may include contacting the biofilm with a composition...
2019/0083618 METHODS OF REDUCING PARTICLE FORMATION AND COMPOSITIONS FORMED THEREBY
Biopharmaceutical compositions and drug products disclosed herein exhibit reduced amounts of subvisible particle formation. Compositions and drug products...
2019/0083617 PHARMACEUTICAL FORMULATIONS
The invention relates to a liquid pharmaceutical formulation comprising an antibody or antigen-binding fragment thereof, cyclodextrin and methionine. In...
2019/0083616 TARGETING IMMUNOTHERAPY FOR AMYLOIDOSIS
Disclosed are methods and compositions for targeting antibodies to amyloid deposits. For example, amyloid-reactive peptides that bind amyloid deposits are...
2019/0083615 ANTI-LAG3 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgous monkey LAG3 as well as...
2019/0083614 ANTI-LAG3 ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS
The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgous monkey LAG3 as well as...
2019/0083613 TN VACCINE COMPOSITION AND METHOD FOR ALLEVIATING INFLAMMATION
The present invention develops a vaccine composition against and treatment or prevention on inflammation and lung injury (particularly hyperoxia-induced lung...
2019/0083612 ANTI-PD-1 ANTIBODIES AND METHODS OF USE THEREOF
The present invention provides antagonizing antibodies that bind to programmed cell death protein 1 (PD-1) and methods of using same. The anti-PD-1 antibodies...
2019/0083611 A Composition Comprising PIC For Treatment Of Cancer
The present disclosure relates to a composition comprising PIC for treatment of cancer. More particularly, the present disclosure discloses a composition for...
2019/0083610 BACTERIOPHAGE-POLYMER HYBRID
The invention provides a targeted bacteriophage-polymer complex comprising a recombinant targeted-bacteriophage and a cationic polymer. The complex has a net...
2019/0083609 TOFACITINIB AS VACCINATION IMMUNE MODULATOR
The invention relates to a pharmaceutical composition comprising Tofacitinib or a pharmaceutically acceptable salt thereof, and at least one antigen, allergen...
2019/0083608 RECOMBINANT HANSENULA POLYMORPHA-BASED HIGH DOSAGE HEPATITIS B VACCINE
Provided is a recombinant Hansenula polymorpha-based high dosage hepatitis B vaccine, an HBsAg pure stock solution yield of a recombinant Hansenula polymorpha...
2019/0083607 CHIMERIC HEPATITIS D VIRUS ANTIGEN AND HEPATITIS B VIRUS PRE S1 GENES FOR USE ALONE OR IN VACCINES CONTANING...
Disclosed herein are chimeric genes, compositions of chimeric genes, and compositions of polypeptides that are useful for the generation, enhancement, or...
2019/0083606 HERPES SIMPLEX VIRUS NANOEMULSION VACCINE
The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition...
2019/0083605 RESPIRATORY SYNCYTIAL VIRUS VACCINE
Described is a vaccine against Respiratory Syncytial Virus (RSV). More specifically, described is a recombinant subunit vaccine comprising the ectodomain of...
2019/0083604 HENDRA AND NIPAH VIRUS G GLYCOPROTEIN IMMUNOGENIC COMPOSITIONS
This invention relates to Hendra virus and Nipah virus immunogenic compositions and methods of use. The invention further relates to immunogenic compositions...
2019/0083603 REMOVAL OF RESIDUAL CELL CULTURE IMPURITIES
The present application discloses methods for removing residual impurities from protein preparations. Such methods include addition of an anionic detergent to...
2019/0083602 METHOD FOR PRODUCING RNA MOLECULE COMPOSITIONS
The invention relates to a method for producing a ribonucleic acid (RNA) molecule composition comprising n different RNA molecule species, the method...
2019/0083601 RECOMBINANT ZIKA VACCINES
The present invention relates to the provision of immunogenic or vaccine compositions comprising at least one recombinant Zika virus antigen, wherein the at...
2019/0083600 RESPIRATORY SYNCYTIAL VIRUS HAVING CLEAVAGE-RESISTANT G PROTEIN AND RELATED MATERIALS AND METHODS
Embodiments disclosed herein provide compositions, methods, and uses for respiratory syncytial viruses (RSV) and immunogenic compositions thereof. Certain...
2019/0083599 Compositions and Methods for Treating an Inflammatory Disease or Disorder
The invention relates to compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof. In certain aspects, the...
2019/0083598 VACCINE FOR IMMUNIZATION AGAINST Q-FEVER
A vaccine includes at least one bacterial antigen capable of producing an immune response in a host when the vaccine is administered at a dose that is...
2019/0083597 AN IMPROVED ADENOVIRUS BASED MALARIA VACCINE ENCODING AND DISPLAYING A MALARIA ANTIGEN
The present invention relates to novel vaccines against malaria infections, based on recombinant adenovirus vectors. Described are capsid modified replication...
2019/0083596 Compositions and Methods for Treating Cancer with DuoCARs
Novel therapeutic immunotherapy compositions comprising at least two vectors, each vector encoding a functional CAR, whereby the combination of vectors results...
2019/0083595 METHODS FOR TREATING NETOSIS AND NEUTROPHIL ACTIVATION
Described herein are methods and compositions relating to methods of inhibiting neutrophils, e.g., inhibiting NET release or NETosis, by means of a DEspR...
2019/0083594 AQUAPORIN TOLERIZING VACCINES AND METHODS OF USE THEREOF
The instant disclosure provides aquaporin DNA tolerizing vaccines and methods of using such vaccines for treating individuals having neuromyelitis optica (NMO)...
2019/0083593 Individualized Vaccines for Cancer
The present invention relates to a patient-specific tumor treatment targeting individual expression patterns of tumor antigens, in particular shared tumor...
2019/0083592 IMMUNOSTIMULATORY COMBINATIONS
The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain...
2019/0083591 PEPTIDES
The present invention relates to novel peptides derived from Progesterone-associated endometrial protein (PAEP), complexes comprising such peptides bound to...
2019/0083590 Development of Dual Whole Cell-Based Vaccine against Pancreatic Cancer
Disclosed herein is a different and novel approach to cancer vaccines using a subject's own dendritic cells (DCs) and macrophages (Mphs) in combination to...
2019/0083589 METHODS FOR PRODUCING PEPTIDES AND USES THEREOF
The present disclosure relates to processes for the production of peptides and methods of using peptides produced accordingly. Peptides produced according to...
2019/0083588 METHOD FOR TREATING AXONS WITH BOTULINUM TOXIN
This disclosure relates to methods and compositions for inducing growth of peripheral nervous system neurons using an effective amount of a botulinum toxin....
2019/0083587 Coagulation factor-targeting to TLT-1 on activated platelets
The current invention relates to: procoagulant proteins which may, for example, be fusion proteins or chemical conjugates; methods of producing said...
2019/0083586 NOVEL METHOD FOR PREVENTING AND TREATING ANGIOCARDIOPATHY
The present invention relates to the effect of plasminogen in the treatment and/or elimination of angiocardiopathy, especially angiocardiopathy caused by...
2019/0083585 Compositions and Methods for Treating Celiac Sprue Disease
Disclosed herein are compositions and methods for treating celiac sprue.
2019/0083584 DIFFUSION ENHANCING COMPOUNDS AND THEIR USE ALONE OR WITH THROMBOLYTICS
The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from...
2019/0083582 INTRAVENTRICULAR ENZYME DELIVERY FOR LYSOSOMAL STORAGE DISEASES
Lysosomal storage diseases can be successfully treated using intraventricular delivery of the enzyme which is etiologically deficient in the disease. The...
2019/0083581 ANTIBACTERIAL COMPOSITION CONTAINING ADK PROTEIN AS ACTIVE INGREDIENT, OR COMPOSITION FOR PREVENTING OR...
The present invention relates to an antibacterial composition containing, as an active ingredient, adenylate kinase or adenosine kinase (ADK) protein derived...
2019/0083580 USE OF ENDOSTATIN PEPTIDES FOR THE TREATMENT OF FIBROSIS
C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and...
2019/0083579 COMPOSITION FOR TREATING DIABETES COMPRISING LONG-ACTING INSULIN CONJUGATE AND LONG-ACTING INSULINOTROPIC...
The present invention relates to a composition for the prevention or treatment of diabetes comprising a long-acting insulin conjugate and a long-acting...
2019/0083578 USE OF LOW DOSE GLUCAGON
The present invention provides methods for controlling or reducing caloric intake in a subject by administering a low dose of a stable glucagon formulation....
2019/0083577 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME
The present invention relates to extended recombinant polypeptide (XTEN) compositions, conjugate compositions comprising XTEN and XTEN linked to cross-linkers...
2019/0083576 CARRIER-FREE BIOLOGICALLY-ACTIVE PROTEIN NANOSTRUCTURES
The present disclosure provides compositions and methods for efficient and effective protein delivery in vitro and in vivo. In some aspects, proteins are...
2019/0083575 THERAPEUTIC EFFECTS OF BRYOSTATINS, BRYOLOGS, AND OTHER RELATED SUBSTANCES ON HEAD TRAUMA-INDUCED MEMORY...
The invention provides for the use of protein kinase activators or boosters of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) or other...
2019/0083574 THERMOGENIC COMPOSITIONS AND METHODS
Thermogenic molecules and methods of using these molecules for treating or preventing a condition in a subject selected from the group consisting of visceral...
2019/0083573 DESIGNER RECEPTORS FOR MODULATING PAIN AND METHODS OF USE THEREOF
The present disclosure provides a method for modulating pain in a subject comprising activating an exogenous receptor expressed in a target neuron with an...
2019/0083572 COMPOSITIONS AND METHODS FOR TREATING A VIRAL INFECTION
One aspect of the present invention provides methods of treating a viral infection in a subject including administrating a therapeutically effective amount of...
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