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Patent # Description
2019/0093149 ASSAYS FOR DETECTING MULTIPLE TICK-BORNE PATHOGENS
Kits, methods, and material for use in detecting tick-borne microorganism(s) are provided herein. One is able to detect DNA from several different species of...
2019/0093148 GENETIC TESTING FOR PREDICTING RESISTANCE OF SERRATIA SPECIES AGAINST ANTIMICROBIAL AGENTS
The invention relates to a method of determining an infection of a patient with Serratia species potentially resistant to antimicrobial drug treatment, a...
2019/0093147 PURIFICATION PROCESS OF NASCENT DNA
The invention relates to a method for initiating the replication of a deoxyribonucleic acid molecule, said method comprising a step of inserting, into said...
2019/0093146 METHODS OF IDENTIFYING MULTIPLE EPITOPES IN CELLS
The invention provides methods, compositions, kits and devices for the detection of target molecules. In some embodiments, the invention allows for multiplexed...
2019/0093145 METHOD FOR DETECTING slow-VISA
Described herein is a method for detecting slow-VISA from clinical samples.
2019/0093144 TISSUE TESTER
A tissue tester for providing an indication of the presence of disease including a first paper tissue sheet; and a filter patch treated with a color changing...
2019/0093143 Methods for Producing Polypeptides in Protease-Deficient Mutants of Trichoderma
The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more (several) genes...
2019/0093142 IMPROVED FERMENTATION PROCESS
A method for producing a recombinant protein of interest (POI) is provided, comprising the steps of (a) culturing cells in a cell culture medium to express...
2019/0093141 BIOSYNTHESIS OF EVERNINOMICIN ANALOGS IN MICROMONOSPORA CARBONACEA VAR AURANTIACA
Disclosed are methods of preparing everninomicin analogs by genetic alteration of Micromonospora carbonacea. Everninomicin analogs prepared by these methods...
2019/0093140 ENZYMATIC SYSTEMS AND METHODS FOR SYNTHESIZING NICOTINAMIDE MONONUCLEOTIDE AND NICOTINIC ACID MONONUCLEOTIDE
Enzyme-based systems and methods for synthesizing the NAD precursors NMN and NaMN are disclosed. Such methods and systems utilize a mutated form of...
2019/0093139 FERMENTATIVE PROCESS FOR THE MANUFACTURE OF MALTOSYL-ISOMALTOOLIGOSACCHARIDES (MIMO)
Described herein are efficient, low cost methods for making prebiotics that contain maltosyl-isomaltooligosaccharides (MIMOs), as well as compositions made by...
2019/0093138 MICROORGANISMS FOR PRODUCING GLYCOGEN AND METHODS OF USING SAME
Recombinant microorganisms configured for increased glycogen production. The recombinant microorganisms comprise a recombinant nucleic acid configured to...
2019/0093137 PROCESS FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL AND FERMENTATION OF SUGARS
The invention relates to a process for the preparation of a fermentation product from ligno-cellulosic material, comprising the following steps: a) optionally...
2019/0093136 PROCESS FOR ENZYMATIC HYDROLYSIS FROM A MIXTURE OF PRE-TREATED SUBSTRATES OF DIFFERENT POROSITIES
The present invention relates to a process for enzymatic hydrolysis in which, under agitation, pre-treated lignocellulosic substrates are brought into contact...
2019/0093135 GENETICALLY ENGINEERED MICROBES AND METHODS FOR PRODUCING CITRAMALATE
Provided herein is a genetically engineered microbe which accumulates citramalate. In one embodiment, the microbe includes an exogenous polynucleotide encoding...
2019/0093134 METHOD AND DEVICE FOR FERMENTATION INTEGRATED WITH SEPARATION AND PURIFICATION OF BUTANOL
The disclosure relates to a method for fermentation integrated with separation and purification of acetone, butanol, and ethanol (ABE) or butanol alone,...
2019/0093133 SEQUENTIALLY-FED PROCESS FOR ENZYMATIC HYDROLYSIS WITH ADDITIONS OF PRE-TREATED SUBSTRATE INCREASINGLY SPREAD...
The present invention relates to a sequentially fed process for enzymatic hydrolysis in which, under agitation, a pre-treated lignocellulosic substrate is...
2019/0093132 METHOD OF MANUFACTURING CHEMICAL AND METHOD OF CULTURING MICROORGANISM
A method of producing a chemical product includes culturing a microorganism with a fermentation feedstock containing cane molasses as a main component;...
2019/0093131 DRIMENOL SYNTHASES III
The present invention discloses a method of producing drimenol and/or drimenol derivatives by contacting a polypeptide with farnesyl pyrophosphate. Also...
2019/0093130 ORGANISMS AND BIOSYNTHETIC PROCESSES FOR HYDROCARBON SYNTHESIS
Methods for biosynthesising hydrocarbons from a gaseous substrate in non-naturally occurring acetogens as well as non-naturally occurring acetogens for...
2019/0093129 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific...
2019/0093128 METHODS FOR GENOME EDITING IN ZYGOTES
The present disclosure provides methods of modifying the genome of a mammalian zygote. The present disclosure provides methods of modulating transcription in a...
2019/0093127 SINGLE CYCLE REPLICATING ADENOVIRUS VECTORS
This document relates to adenovirus vectors and methods and materials related to using adenovirus vectors. For example, viruses, nucleic acid molecules...
2019/0093126 LARGE COMMERCIAL SCALE LENTIVIRAL VECTOR PRODUCTION SYSTEM AND VECTORS PRODUCED THEREBY
In accordance with the present invention, a method for increasing the yield of rLV vector particles comprising a trans gene encoding a therapeutic protein or...
2019/0093125 HIGH EFFICIENCY, HIGH THROUGHPUT GENERATION OF GENETICALLY MODIFIED NON-HUMAN MAMMALS BY MULTI-CYCLE...
The invention described herein provides high throughput methods and reagents for generating transgenic animals (e.g., non-human mammals) through introducing a...
2019/0093124 TRANSGENIC CLONED PIGLET EXPRESSING HUMAN PROINSULIN AND METHOD OF PRODUCING THE SAME
A transgenic cloned piglet expressing human proinsulin and a method of preparing the same, and more particularly, to a recombinant vector for human proinsulin...
2019/0093123 NUCLEOTIDE SEQUENCES AND CORRESPONDING POLYPEPTIDES CONFERRING IMPROVED NITROGEN USE EFFICIENCY CHARACTERISTICS...
Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen ...
2019/0093122 ENGINEERING CRASSULACEAN ACID METABOLISM (CAM) PATHWAYS IN PLANTS
Disclosed herein are method of altering CAM pathways in plants. In some examples, a disclosed method includes overexpressing one or more genes encoding one or...
2019/0093121 USE OF UMP-CMP KINASES FOR INCREASING NITROGEN USE EFFICIENCY AND LOW NITROGEN TOLERANCE IN PLANTS
Provided are methods of increasing nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress...
2019/0093120 SORGHUM YIELD ENHANCEMENT GENE MULTI-SEEDED 3 (MSD3)
This invention relates to novel mutations in a sorghum gene, Msd3, which increase the seed yield in sorghum. The nucleic acid sequences of this mutated gene...
2019/0093119 METHODS AND COMPOSITIONS FOR INCREASING EXPRESSION OF GENES OF INTEREST IN A PLANT BY CO-EXPRESSION WITH P21
Methods and compositions are provided for increasing the expression of a gene of interest in a plant by co-expressing the gene of interest with a p21...
2019/0093118 GENE COMBINATION AND USE THEREOF
Provided are a gene combination used for controlling foreign gene expression in a specific plant tissue, and a method applying the gene combination to...
2019/0093117 METHODS AND COMPOSITIONS FOR VIRAL-BASED GENE EDITING IN PLANTS
The present disclosure provides compositions and methods for editing a target site of a plant genome by delivery of functional editing components using...
2019/0093116 RECOMBINANT YEAST STRAINS
This invention relates to genetically engineered strains of yeast and methods, for producing recombinant protein (e.g., collagen). Recombinant protein of the...
2019/0093115 NOVEL GENE TARGETING METHOD
A novel gene targeting method and a nucleotide construct for the method. The method integrates a nucleotide construct containing an interference gene in an...
2019/0093114 FUNGAL GENOME MODIFICATION SYSTEMS AND METHODS OF USE
Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. The methods and compositions are drawn to a...
2019/0093113 SHUTTLE VECTOR, PROKARYOTIC HOST CELLS AND KIT COMPRISING THE SAME, AND METHOD FOR PRODUCING PROTEINS VIA THE...
The present application provides a shuttle vector which can be manipulated in various kinds of host cells, thereby providing a novel tool for the field of...
2019/0093112 BIOSYNTHETIC GENE CLUSTER OF CARRIMYCIN
The present disclosure provides a biosynthetic gene cluster of carrimycin. The biosynthetic gene cluster comprises 44 gene open reading frames (orf), i.e., 5...
2019/0093111 AAV VECTORS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA
Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and...
2019/0093110 Novel System for the Biocontrol of Disease-Transmitting Mosquitoes and Their Eggs Using Horizontally...
The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel...
2019/0093109 COMPOSITIONS AND METHODS TO PROMOTE BONE FORMATION
This disclosure relates to methods for promoting bone formation or reducing bone destruction. This disclosure also relates to methods for promoting the...
2019/0093108 Methods and Compositions for Increased Double Stranded RNA Production
Methods and materials for improved in vivo production of dsRNA are presented. Yields of dsRNA are significantly increased in the presence of capsid protein....
2019/0093107 NOVEL CRISPR ENZYMES AND SYSTEMS
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or...
2019/0093106 COMPOSITIONS AND METHODS FOR TREATING DIABETIC RETINOPATHY
The application discloses compositions and methods for preventing and treating diabetic retinopathy. It is disclosed herein that an inhibitor of...
2019/0093105 EXOSOME PACKAGING OF NUCLEIC ACIDS
A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise:...
2019/0093104 COEXPRESSION OF CAS9 AND TREX2 FOR TARGETED MUTAGENESIS
A composition used in targeted mutagenesis is provided, which includes a first expression cassette comprising a nucleotide sequence which encodes a CAS9...
2019/0093103 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead...
2019/0093102 ENRICHMENT OF SHORT NUCLEIC ACID FRAGMENTS IN SEQUENCING LIBRARY PREPARATION
Methods for preparing enriched sequencing libraries from test samples that contain double-stranded deoxyribonucleic acid (dsDNA) are provided.
2019/0093101 ANTIGEN BINDING MOLECULES AND METHODS OF USE THEREOF
Isolated antigen binding molecules that specifically binds to a molecule comprising an amino acid sequence selected from the group consisting of GGGS (SEQ ID...
2019/0093100 MODIFYING BACTERIOPHAGE
A method for producing one or more hybrid bacteriophage host range determinant (HRD) sequences, which comprises: (1) identifying at least two DNA sequences,...
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