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Patent # Description
2019/0092897 NOVEL COMPOSITIONS FOR POLYURETHANE APPLICATIONS
A process comprising, consisting of, or consisting essentially of: foaming a reaction mixture containing at least one polyisocyanate and an isocyanate-reactive...
2019/0092896 A CURABLE URETHANE ACRYLATE COMPOSITION WITH BIMODAL OF MOLECULAR WEIGHT DISTRIBUTION
A curable resin composition comprising: (1) a urethane (meth)acrylate comprising a) urethane (meth)acrylate oligomers with a number average molecular weight in...
2019/0092895 ENERGETIC COMPOUNDS AND COMPOSITIONS
Energetic nitrogen-rich monomers represented by the general Formula I: ##STR00001## wherein each of X1 and X2 is independently NR or a covalent bond, R is H or...
2019/0092894 NOVEL COMPOSITIONS AND METHODS TO PRODUCE ALKOXYLATED TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES
The embodiments described herein generally relate to methods and chemical compositions of triazine-arylhydroxy-aldehyde condensates. In one embodiment, a...
2019/0092893 Production Of Polyurethane Systems
The invention provides a process for production of polyurethane systems by reacting at least one polyol component with at least one isocyanate component in the...
2019/0092892 CROSSLINKED POLYMERS AND A METHOD FOR HEAVY METAL ION REMOVAL
Crosslinked polymers made up of polymerized units of cyclic diaminoalkane, aldehyde and bisphenol-S or melamine. A method for removing heavy metals, such as...
2019/0092891 Polymer Latex for Dip-Molding Applications
The present invention relates to a polymer latex for dip-molding applications obtainable by free-radical emulsion polymerization of a mixture of ethylenically...
2019/0092890 METHOD FOR PRODUCING COPOLYMER, AND METHOD FOR PRODUCING LATEX
The invention is a method for producing a copolymer having a repeating unit derived from a conjugated diene-based monomer and using a radical polymerization...
2019/0092889 THERMOSETTING RESIN COMPOSITION
It is an object of the present invention to provide a thermosetting resin composition using a transesterification reaction as a curing reaction, which has a...
2019/0092888 MULTI-BASE MATERIAL ADAPTIVITY PULLING REMOVAL TYPE BINDER PRODUCT, BINDER COMPOSITION AND ASSEMBLY
The present disclosure provides a multi-base material adaptivity pulling removal type binder product, a binder composition and an assembly. The binder product...
2019/0092887 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION...
The metallocene compound represented by the following general formula (1): ##STR00001## (the numerals and signs in the general formula (1) are as described in ...
2019/0092886 METHODS OF MONITORING AND CONTROLLING THE MELT INDEX OF A POLYOLEFIN PRODUCT DURING PRODUCTION
Methods for producing polyolefin polymers may use a predictive melt index regression to estimate the melt index of the polyolefin during production based on...
2019/0092885 Modulating Interfacial Wettability of a Noncovalent Nanoscopic Ligand Film
This invention generally relates to a method for modulating interfacial wettability of a noncovalent nanoscopic monolayer or thin film. Particularly, this...
2019/0092884 CYCLIC POLYOLEFINS DERIVED FROM HEXYNE, OCTYNE, NONYNE, PENTADECYNE AND THEIR COPOLYMERS WITH ACETYLENE
Disclosed are saturated cyclic monopolymers derived from hexyne, octyne, nonyne, pentadecyne and saturated cyclic copolymers derived from acetylene and a...
2019/0092883 SYNTHETIC POLYMER FILM WHOSE SURFACE HAS MICROBICIDAL ACTIVITY, PHOTOCURABLE RESIN COMPOSITION, MANUFACTURING...
A synthetic polymer film is a synthetic polymer film whose surface has a plurality of raised or recessed portions. The synthetic polymer film has a crosslink...
2019/0092882 Oxygen Permeable Monomers, Polymers and Ionomers and Methods of Making the Same
An oxygen permeable polymer has the following formula: ##STR00001## wherein R.sub.S is a non-sulfonyl halide portion of a sulfonyl halide monomer or polymer;...
2019/0092881 ALKYL METALLOXANE COMPOUND AND METHOD FOR PRODUCING THE SAME
An alkyl metalloxane compound and a method of producing the same are provided. The alkyl metalloxane compound includes one or more alkyl aluminoxane structural...
2019/0092880 GEL WITH SELF-RESTORABILITY AND SHAPE-MEMORY PROPERTY AND PROCESS FOR PRODUCING SAME
The present invention provides a gel formed by a host-guest interaction and having self-healing and shape-memory properties, and a process for producing the...
2019/0092879 METHOD FOR PRODUCING A PROPHYLACTIC ARTICLE
According to a method for the manufacture of a prophylactic article, especially of a glove, from a (carboxylated) diene rubber, at least one layer of a...
2019/0092877 ANTI-PCSK9-GLP-1 FUSIONS AND METHODS FOR USE
This application provides anti-PCSK9.about.GLP-1 fusions and methods for use.
2019/0092876 T-CELL RECEPTOR MIMIC (TCRM) ANTIBODIES
The present invention provides an antibody which binds to human p53 tumour suppressor protein residues 65-73 (human p53.sub.65-73), as shown in SEQ ID NO: 1,...
2019/0092875 DEPLETING TUMOR-SPECIFIC TREGS
The present invention provides, among other things, methods and compositions for diagnosing and/or treating cancer by targeting CCR8. In particular, the...
2019/0092874 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER
A novel gene 0161P2F10B (also designated 161P2F10B) and its encoded protein, and variants thereof, are described wherein 161P2F10B exhibits tissue specific...
2019/0092873 CD47 TARGETED THERAPIES FOR THE TREATMENT OF INFECTIOUS DISEASE
Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a...
2019/0092872 ANTIBODY FC AND FAB VARIANTS
The present invention relates to modified antibodies. In particular, the present invention relates to recombinant monoclonal antibodies or fragments, including...
2019/0092871 CD20 BINDING SINGLE DOMAIN ANTIBODIES
The present application relates, in part, to agents that bind CD20 and their use as therapeutic agents. The present application further relates to...
2019/0092870 ANTI-TfR ANTIBODIES AND THEIR USE IN TREATING PROLIFERATIVE AND INFLAMMATORY DISORDERS
The present invention relates to humanized antibodies that specifically bind to human transferrin receptor and their use in treating cancer and inflammatory...
2019/0092869 ANTAGONISTIC ANTI-OX40L ANTIBODIES AND METHODS OF THEIR USE
Described herein are methods and compositions for treating autoimmunity and inflammatory conditions without non-specific suppression of the host immune system....
2019/0092868 ANTI-CD40L ANTIBODIES AND METHODS FOR TREATING CD40L-RELATED DISEASES OR DISORDERS
Anti-human CD40L antibodies engineered to lack the ability to activate platelets and methods for treating patients having a CD40L-associated disease.
2019/0092867 ANTI-CXCR4 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
The present invention provides antibodies and related molecules that bind to chemokine receptor 4 (CXCR4). The invention further provides antibody-drug...
2019/0092866 BINDING PROTEINS AND METHODS OF USE THEREOF
The present disclosure provides binding proteins, such as antibodies, that bind to a GDNF Family Receptor Alpha Like (GFRAL) protein, including human GFRAL...
2019/0092865 ANTI-DEspR INHIBITORS AS THERAPEUTICS FOR INHIBITION OF PATHOLOGICAL ANGIOGENESIS AND TUMOR CELL INVASIVENESS...
Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof, including fully human, composite engineered human, humanized,...
2019/0092864 TUMOR MUTATIONAL LOAD
The present invention encompasses the discovery that the likelihood of a favorable response to cancer immunotherapy for a wide range of different cancers can...
2019/0092863 CANCER IMMUNOTHERAPY BY DISRUPTING PD-1/PD-L1 SIGNALING
The disclosure provides a method for immunotherapy of a subject afflicted with cancer, comprises administering to the subject a composition comprising a...
2019/0092862 MULTISPECIFIC FAB FUSION PROTEINS AND USE THEREOF
The present invention provides multispecific Fab fusion proteins (MSFP) that specifically bind to CD3 and EpCAM. The present invention further provides uses of...
2019/0092861 ANTIGEN BINDING PROTEINS THAT BIND PD-L1
There is disclosed anti-PD-L1 IgG class antibodies that have an improved ability to be manufactured at higher yields. More specifically, there is disclosed...
2019/0092860 Covalent Diabodies and Uses Thereof
The present invention is directed to diabody molecules and uses thereof in the treatment of a variety of diseases and disorders, including immunological...
2019/0092858 CD31SHED AS A MOLECULAR TARGET FOR IMAGING OF INFLAMMATION
Disclosed is CD31.sup.shed for use as a molecular imaging target in the molecular imaging of an inflammatory condition. Administering the radiolabeled peptide...
2019/0092857 METHOD OF MODULATING THE ACTIVITY OF ADRENOMEDULLIN IN A SUBJECT IN NEED OF THERAPEUTIC INTERVENTION FOR ORGAN...
Subject matter of the present invention is an anti-adrenomedullin (ADM) antibody or an anti-adrenomedullin antibody fragment or an anti-ADM non-Ig scaffold for...
2019/0092856 Human Oncostatin M Antibodies and Methods of Use
Antibodies and compositions capable of neutralizing oncostatin M biological functions are useful in treating diseases and disorders associated with oncostatin...
2019/0092855 Polypeptides
There is provided inter alia a polypeptide comprising an immunoglobulin chain variable domain which binds to IL-6R, wherein the immunoglobulin chain variable...
2019/0092854 Interleukin-31 Monoclonal Antibody
A cell-based assay for assessing the functional activity of a canine or feline IL-31 inhibitor candidate is provided. Such a canine or feline IL-31 inhibitor...
2019/0092853 Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 Antibody
A method of treating active Systemic Lupus Erythematosus (SLE) in a patient by administering a clinically proven safe and clinically proven effective amount of...
2019/0092852 ANTI-INTERLEUKIN-33 ANTIBODIES AND USES THEREOF
The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
2019/0092851 ANTIBODY MOLECULES TO APRIL AND USES THEREOF
Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA...
2019/0092850 Anti-TNFalpha-Antibodies and Functional Fragments Thereof
The present invention relates to antibody molecules and functional fragments thereof, capable of binding to tumor necrosis factor alpha (TNF.alpha.), to...
2019/0092849 ANTI-TNF ANTIBODIES, COMPOSITIONS, METHODS AND USE FOR THE TREATMENT OR PREVENTION OF TYPE 1 DIABETES
The present invention relates to compositions and methods utilizing anti-TNF antibodies having a heavy chain (HC) comprising SEQ ID NO:36 and a light chain...
2019/0092848 Methods of treating bone diseases, disorders and/or injuries and reagents therefor
The present disclosure relates to methods and reagents for treating bone disorders and/or increasing bone healing. In particular, present disclosure relates to...
2019/0092847 TGF- 1 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOF
Specific binding members, particularly antibodies and fragments thereof, which bind to transforming growth factor beta 1 (TGF-.beta.1) are provided,...
2019/0092846 TGFbeta 2 Antibodies
This invention is in the field of anti-transforming growth factor beta 2 (TGF-.beta.2) antibodies. In particular, the invention provides human monoclonal...
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