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Patent # Description
2019/0091326 POLYPEPTIDE GLYCOPEPTIDE FRAGMENTS FROM THE V1/V2 AND V3 DOMAINS OF THE HIV-1 ENVELOPE PROTEIN GP 120
Creation of HIV-1 vaccine immunogens based on glycopeptide scaffolds containing sequences from the V1/V2/V3 and C3 domains of HIV-1 gp120 that is able to bind...
2019/0091325 HUMAN ROTAVIRUS G9P[6] STRAIN AND USE AS A VACCINE
Attenuated G9P[6] rotavirus is disclosed herein. In some embodiments, pharmaceutical compositions are disclosed that include an attenuated G9P[6] rotavirus, or...
2019/0091324 NASAL INFLUENZA VACCINE COMPOSITION
The invention relates to an influenza vaccine composition for spray-administration to nasal mucosa, which comprises an inactivated whole influenza virion and a...
2019/0091323 UNIVERSAL VIRUS-LIKE PARTICLE (VLP) INFLUENZA VACCINES
Described herein are influenza virus-like particles (VLPs) that display on truncated, re-engineered or remodeled HA molecules on their surface. Also described...
2019/0091322 DNA ANTIBODY CONSTRUCTS AND METHOD OF USING SAME
Disclosed herein is a composition comprising the combination of a nucleic acid sequence encoding a desired polypeptide that elicits an immune response in a...
2019/0091321 A COMBINATION VACCINE AGAINST PCV2 AND PRRS VIRUS INFECTION COMPRISING ALBUMIN
The present invention pertains to a vaccine for use in prophylactically treating an animal against an infection with porcine circovirus type 2 (PCV2) and an...
2019/0091320 CHIMERIC PORCINE CIRCOVIRUS TYPE 2 (PCV2) VACCINES
Vaccine compositions and methods are described for providing immunity to porcine circovirus type two (PCV2) genotypes including by administration of a...
2019/0091319 P AERUGINOSA PCRV-LINKED ANTIGEN VACCINES
The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier...
2019/0091318 ADHESIN TIP MULTIEPITOPE FUSION ANTIGEN PLATFORM AND VACCINES AND THEIR USE IN THE TREATMENT OF ENTEROTOXIGENIC...
The application provides for MEFA constructs and vaccines against Entertoxigenic Escherichia coli (ETEC). Methods for reducing the incidence of diarrhea...
2019/0091317 ATTENUATED PISCIRICKETTSIA SALMONIS BACTERIUM
The present invention relates to an attenuated Piscirickettsia salmonis bacterium. The bacterium comprises mutations in the amino acid sequence of each of the...
2019/0091316 Subcutaneous Delivery of Adenovirus with Dual Targeting
Immunotherapeutic methods and compositions are contemplated in which neoepitopes and/or tumor associated antigens are delivered to dendritic cells via an...
2019/0091315 IMMUNITY-INDUCING AGENT
The present application relates to a novel immunity-inducing agent for treatment and/or prevention of cancer. Specifically, the present application provides an...
2019/0091314 Novel peptides and combination of peptides and scaffolds for use in immunotherapy against Renal Cell Carcinoma...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2019/0091313 Novel peptides and combination of peptides and scaffolds for use in immunotherapy against Renal Cell Carcinoma...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2019/0091312 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST BREAST CANCER AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2019/0091311 Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
A method of treating a patient who has prostate cancer includes administering to said patient a composition containing a population of activated T cells that...
2019/0091310 NONRELEASED IL-12 FOR THERAPY OF CANCER
The present invention includes compositions and methods comprising: a cancer antigen-specific chimeric antigen receptor cells, e.g., alpha-beta cell receptor T...
2019/0091309 Use of Car and Bite Technology Coupled with an SCFV from an Antibody Against Human Thymidine Kinase 1 to...
Modified T-cells have paratopes against human TK1 epitopes, are made by producing monoclonal antibodies that are specific to TK1, creating chimeric antigen...
2019/0091308 METHODS AND COMPOSITIONS FOR CAR T CELL THERAPY
The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small...
2019/0091307 PTPS-BASED VACCINES AGAINST CANCER
The present invention relates to the field of medicine. It more particularly relates to peptides, microvesicles containing such peptides, compositions...
2019/0091306 METHOD FOR VACCINATION AGAINST A SELF-ANTIGEN IN A HUMAN PATIENT
Disclosed is a method for vaccination against a self-antigen in a human patient wherein a dose with an effective amount of a self-antigen is administered to...
2019/0091305 GLYCOSIDASE REGIMEN FOR TREATMENT OF INFECTIOUS DISEASE
In various aspects, the invention relates to immune tolerant glycosidase therapy. The invention provides methods for treating or preventing infectious disease,...
2019/0091304 NOVEL PROTEIN MATERIAL
The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate hi an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin...
2019/0091303 SINGLE-DOSE ADMINISTRATION OF FACTOR VIIa
The present invention provides methods for preventing and/or treating bleeding episodes by administering a single dose of a Factor VIIa equivalent. Preferably,...
2019/0091302 USE OF HYALURONIDASE FOR THE PREVENTION OR TREATMENT OF ARTERIAL HYPERTENSION OR CARDIAC INSUFFICIENCY
The present invention relates to the use of hyaluronidase for the prevention and/or treatment of arterial hypertension or cardiac insufficiency. In addition,...
2019/0091301 INTESTINL FLORIDA IMPROVEMENT AGENT
The purpose of the present invention is to provide an agent for improving intestinal flora which can increase the number of beneficial bacteria such as lactic...
2019/0091300 METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM
A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a...
2019/0091299 TREATMENT OF GASTROINTESTINAL BLEEDING IN PATIENTS WITH SEVERE VON WILLEBRAND DISEASE BY ADMINISTRATION OF...
The present invention relates to a method for treating gastrointestinal bleeding in a subject with severe von Willebrand Disease comprising administering to...
2019/0091298 TREATMENT OF PATIENTS WITH SEVERE VON WILLEBRAND DISEASE UNDERGOING ELECTIVE SURGERY BY ADMINISTRATION OF...
The present invention relates to method for pretreating a subject with severe von Willebrand disease prior to a surgical procedure comprising administering to...
2019/0091297 THERAPEUTIC AGENTS COMPRISING ELASTIN-LIKE PEPTIDES
The present invention provides therapeutic agents and compositions comprising elastin-like peptides (ELPs) and therapeutic proteins. In some embodiments, the...
2019/0091296 Glucagon-Like Peptide 1 Receptor Agonists and Uses Thereof
The present invention provides modified glucagon-like peptide 1 (GLP1) polypeptides, fusion proteins comprising modified GLP1 polypeptides, and methods of use...
2019/0091295 Liraglutide in Renal Conditions
The present invention relates to the GLP-1 receptor agonist liraglutide for use in medicine.
2019/0091294 POLYPEPTIDES AND ANALOGUES THEREOF FOR USE IN THE TREATMENT OF DIABETES AND BONE DISORDERS
The present invention relates to polypeptides and analogues thereof for use in the treatment of diabetes and bone disorders. Also disclosed are pharmaceutical...
2019/0091293 SLEEP APNEA TREATMENT
Provided herein is technology relating to treating sleep apnea and particularly, but not exclusively, to treating sleep apnea with immunotherapeutics and/or...
2019/0091292 COMPOSITION FOR DIAGNOSING ALLERGIES TO MITES, METHOD OF DIAGNOSING ALLERGIES TO MITES, AND COMPOSITION FOR...
Mite proteins according to an aspect may be used in diagnosing allergic diseases. Results of diagnosing allergic diseases by using the proteins have high...
2019/0091291 COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISORDERS
The present invention provides a method for the prevention or treatment of a neurodegenerative disorder in a subject, comprising administering to the subject a...
2019/0091290 MACROPHAGE STIMULATION IN CD47 BLOCKADE THERAPY
Blockade of the CD47/SIRPa pathway depletes cancer cells. This anti-cancer activity is enhanced when macrophage stimulating agents are used in combination with...
2019/0091289 HSP For Use in Treatment for Imiquimod Related Side Effects
The invention relates to a healthcare product comprising (i) a component selected from the group of heat shock proteins from alfalfa and heat shock protein...
2019/0091288 TOPICAL PHARMACEUTICAL OR COSMETIC COMPOSITIONS AS WELL AS MEDICAL DEVICES COMPRISING THEREOF FOR THE TREATMENT...
The present invention provides a combination comprising pea protein and a polysaccharide for use in the topical treatment or prevention of a skin disorder...
2019/0091287 PLANT FRACTIONS HAVING ANTI-PATHOGENESIS PROPERTIES
This invention comprises a method of using for anti-pathogenesis effect an improved composition and an improved composition comprising heat stable plant juice...
2019/0091286 USE OF IMMUNOMODULATORY PROTEIN FROM GANODERMA IN INHIBITING FIBROSIS
The present invention provides a method of preventing or treating fibrosis in a subject, comprising administering an effective amount of an immunomodulatory...
2019/0091285 ORAL OCTREOTIDE ADMINISTERED IN COMBINATION WITH OTHER THERAPEUTIC AGENTS
This invention relates to combination therapy of a subject suffering from acromegaly. The method of treatment comprises administration to the subject of a...
2019/0091284 Amidated Dopamine Neuron Stimulating Peptides for CNS Dopaminergic Upregulation
The present invention relates to novel proteins, referred to herein as amidated glial cell line-derived neurotrophic factor (GDNF) peptides (or "Amidated...
2019/0091283 COMBINATION THERAPY FOR ISCHEMIA
The invention provides a combination treatment for ischemia conditions in or otherwise affecting the CNS, such as stroke. The treatment involves administration...
2019/0091282 PEPTIDES FOR USE IN PROMOTING TRANSPORT OF GLUCOSE
A natural glucose transport promoting peptide comprising a glucose transport promoting fragment of a protein selected from SEQUENCE ID NO's: 1 to 6, and a...
2019/0091281 DELIVERY PHARMACEUTICAL COMPOSITIONS INCLUDING PERMEATION ENHANCERS
Pharmaceutical compositions having enhanced active component permeation properties are described.
2019/0091280 POLYMERIC NANOPARTICLES AND A PROCESS OF PREPARATION THEREOF
The present invention relates to the field of nanotechnology, in particular, to the production of biodegradable polymeric nanoparticles. The present invention...
2019/0091279 METHODS FOR REDUCING PERINATAL MORBIDITY AND/OR MORTALITY
A method for preventing or reducing the risk of perinatal or neonatal morbidity and mortality caused by antenatal inflammation in humans is described. This...
2019/0091278 PEPTIDE HAVING ANTI-INFLAMMATORY ACTIVITY, AND USE THEREOF
The present invention provides a peptide having anti-inflammatory activity, composed of an amino acid sequence of a sequence listing of SEQ ID NO: 1, SEQ ID...
2019/0091277 METHODS FOR REDUCING PLATELET AGGREGATION AND TREATING CARDIOVASCULAR DISEASE AND OTHER MEDICAL DISORDERS
The invention provides therapeutic compositions containing ground seed of Aframomum meleguata or an extract thereof, and methods for using such compositions to...
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