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Patent # Description
2019/0099459 Methods and compositions for preventing infection by a Vibrio species
Compositions and methods are provided for preventing, ameliorating, or treating a disease caused by a species of bacterial genus Vibrio, for example, cholera...
2019/0099458 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
2019/0099457 Immunomodulatory Composition Comprising Bifidobacteria
The present invention relates to composition derivable from a bifidobacteria, methods and uses thereof, for use in modulating the immune system in a subject by...
2019/0099456 COMPOSITION FOR PROMOTING INTERFERON LAMBDA PRODUCTION AND PRODUCTION METHOD THEREFOR
An object of the present invention is to provide a composition for promoting interferon .lamda. production, which contains an active ingredient exhibiting an...
2019/0099455 COMPOSITIONS AND METHODS
Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of...
2019/0099454 PROBIOTIC BACTERIA FOR THE TOPICAL TREATMENT OF SKIN DISORDERS
The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use...
2019/0099453 MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE
The present invention relates to the use of a compound which inhibits the activity of MKK4 as a medicament for the treatment of a patient suffering from an...
2019/0099452 METHODS FOR PROMOTING OLIGODENDROCYTE REGENERATION AND REMYELINATION
The present invention provides a method for preventing or treating a demyelinating disease in a subject. Also provided herein is a method for reducing...
2019/0099451 RETROVIRAL CONSTRUCT HARBORING A LET-7 INSENSITIVE NUCLEIC ACID ENCODING HMGA2 AND METHODS OF USE THEREOF
A retroviral construct harboring nucleic acids encoding a high mobility group AT-hook 2 (HMGA2) protein and lacking let-7 binding sites is described as are...
2019/0099450 PD-L1 EXPRESSING HEMATOPOIETIC STEM CELLS AND USES
Embodiments disclosed here provide engineered modified hematopoietic stem cells (HSCs), artificially prostaglandin E2 (PGE.sub.2)-stimulated HSCs, compositions...
2019/0099449 Methods of Preserving Mesenchymal Stem Cells
This disclosure relates to methods of preserving mesenchymal stromal/stem cells (MSCs) for use in clinical applications. In certain embodiments, this...
2019/0099448 PREPARATION OF PLATELET PELLET LYSATE AND ITS USE FOR TREATING NEUROLOGICAL DISORDERS
A process for preparing a modified heat-treated platelet pellet lysate, said process comprising the steps of: a) Providing a platelet pellet lysate, b)...
2019/0099447 ADOPTIVE CELL THERAPIES AS EARLY TREATMENT OPTIONS
Provided are methods and compositions for providing early cell therapy options to subjects, offering the potential benefit of avoiding higher risk treatment...
2019/0099446 IMMUNOCOMPETENT CELL AND EXPRESSION VECTOR EXPRESSING REGULATORY FACTORS OF IMMUNE FUNCTION
It is to provide an immunocompetent cell that expresses regulatory factors of immunocompetent cell immune function and possesses all of proliferative...
2019/0099445 A PHARMACEUTICAL OR VETERINARY COMPOSITION
The invention is directed to a pharmaceutical or veterinary composition comprising, when dissolved in a diluent, a strong ion difference in the range of...
2019/0099444 COMPOSITIONS FOR THE TREATMENT OF SWEATING AND METHODS FOR MAKING SAME
The invention describes novel compositions and methods utilized for treating disorders and/or conditions associated with the epidermal and/or dermal level of...
2019/0099443 Modified Immune-Modulating Particles
The current invention involves the surprising finding that when carboxylated particles, such as carboxylated polystyrene, PLGA, or diamond particles are...
2019/0099442 Artificial Invaplex Formulated with Deacylated Lipopolysaccharide
Disclosed herein are artificial Invaplexes comprising deacylated lipopolysaccharides and methods of making and using thereof.
2019/0099441 OPHTHALMOLOGICAL COMPOSITION
The present invention relates to an ophthalmological composition with high viscosity. The composition according to the invention comprises or thereby consists...
2019/0099440 METHOD FOR OLFACTORY IMPROVEMENT WITH SACCHARIDE
A method for olfactory improvement with saccharide. The saccharide is a chitin-based material, proteoglycan, glycosaminoglycan, amino monosaccharide,...
2019/0099439 PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS, LIVER FIBROSIS, AND LIVER CANCER
The present invention relates to a pharmaceutical composition for treating hepatitis, liver fibrosis, and liver cancer, which comprises the following...
2019/0099438 COMPOSITION FOR PREVENTING OR TREATING METABOLISM DISORDERS COMPRISING LEUCONOSTOC MESENTEROIDES-PRODUCING...
The present invention provides a prophylactic or therapeutic composition for a metabolic disorder, a composition for amplifying the amount of short-chain fatty...
2019/0099437 METHOD FOR SUPPRESSING OBESITY, METHOD FOR TREATING OBESITY, AND METHOD FOR PROMOTING GENE EXPRESSION
The present disclosure relates to a method for suppressing obesity, which includes administering to a subject a compound represented by the following formula ...
2019/0099436 SODIUM GLUCOSE CO-TRANSPORTER INHIBITORS AND METHODS OF THEIR USE
Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders...
2019/0099435 Inhibiting inflammation with milk oligosaccharides
A method of inhibiting inflammation with milk oligosaccharides or glycoconjugates containing the oligosaccharides.
2019/0099434 NERIDRONIC ACID FOR TREATING COMPLEX REGIONAL PAIN SYNDROME
Oral dosage forms of osteoclast inhibitors, such as neridronic acid, in an acid or a salt form, can be used to treat or alleviate pain or related conditions,...
2019/0099433 Antibacterial Use of Halogenated Salicylanilides
The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including...
2019/0099432 COMPOSITIONS FOR THE TREATMENT OF CHRONIC VULVAL AND PERINEAL PAIN AND SYMPTOMS AND CONDITIONS ASSOCIATED THEREWITH
Provides herein are compositions for the treatment of chronic vulval or perineal pain, and of symptoms or conditions associated therewith, comprising an...
2019/0099431 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE
The present disclosure provides antibodies, antibody binding fragments, and antibody drug conjugates that bind human LRRC15, their methods of making, and their...
2019/0099430 High Dosage Strength Tablets of Rucaparib
A tablet including high dosage of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[- 5,4,3-cd]indol-6-one camsylate salt has been...
2019/0099429 CENICRIVIROC FOR THE TREATMENT OF FIBROSIS
The present disclosure provides methods of treating fibrosis or a fibrotic disease or condition in a subject in need thereof comprising administering to the...
2019/0099428 COMPOSITIONS AND METHODS FOR PROPHYLAXIS AND THERAPY FOR MENIERE'S DISEASE
Provided are articles of manufacture, compositions and methods for prophylaxis and/or therapy for disorders involving dizziness and/or vertigo. The articles of...
2019/0099427 USE OF A DPP-4 INHIBITOR IN PODOCYTES RELATED DISORDERS AND/OR NEPHROTIC SYNDROME
The present invention relates to methods for treating and/or preventing podocytes related disorders and/or nephrotic syndrome comprising the administration of...
2019/0099426 Advanced Formulations and Therapies for Treating Hard-to-Heal Wounds
A method for healing a hard-to-heal wound including the steps of: topically administering a wound healing composition to a wounded area, wherein the wound...
2019/0099425 COMPOSITIONS AND METHODS OF USE OF CIS-4-[2-{[(3S,4R)-3-FLUOROOXAN-4-YL]AMINO}-8-(2,4,6-TRICHLOROANILINO)-9H- ...
Provided are formulations and dosage forms of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H- ...
2019/0099424 Pharmaceutical Composition for Decreasing The Side Effects of Pancreatic Cancer Drug, and Manufacturing Method...
The present invention provides a pharmaceutical composition comprising a mushroom, a rhizome, a fruit, a leaf, a flower, an alga, an energy-rich liquid, a...
2019/0099423 USE OF MYELOPEROXIDASE (MPO) INHIBITORS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF TO TREAT MULTIPLE SYSTEM...
The present invention relates to the use of MPO inhibitors for the treatment of multiple system atrophy. The present invention also relates to the use of MPO...
2019/0099422 PHARMACEUTICAL COMPOSITION COMPRISING EICOSAPENTAENOIC ACID AND DERIVATIVES THEREOF AND A STATIN
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and a statin and to methods of using the same...
2019/0099421 CINNOLIN-4-AMINE COMPOUNDS AND THEIR USE IN TREATING CANCER
This specification generally relates to compounds of Formula (I): ##STR00001## And pharmaceutically acceptable salts thereof, where R.sup.1, R.sup.2 and...
2019/0099420 SYSTEMS PHARMACOLOGY FOR TREATING OCULAR DISORDERS
A method of treating an ocular disorder in a subject includes administering to the subject subtherapeutic amounts of two or more agents that inhibit and/or...
2019/0099419 PROCASPASE COMBINATION THERAPY FOR GLIOBLASTOMA
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods...
2019/0099418 PROCASPASE 3 ACTIVATION BY COMBINATION THERAPY
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods...
2019/0099417 ABUSE RESISTANT DRUG FORMULATION
A pharmaceutical composition may include a coated particulate which may include at least one active pharmaceutical ingredient, particularly one susceptible to...
2019/0099416 METHODS FOR TREATING PRURITUS
The present invention relates to methods for treating pruritus with anti-pruritic compositions.
2019/0099415 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS
The present invention relates to therapeutic combinations and methods for treating cancers using combination therapy.
2019/0099414 THERAPEUTIC COMPOSITIONS AND METHODS
Therapeutic methods and compositions for treating fibrosis (e.g. scarring) are provided, as well as compositions comprising blebbistatin or a salt thereof and...
2019/0099413 DRUG FOR CANCER THERAPY CHARACTERIZED IN THAT AXL INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR ARE ADMINISTERED IN...
A drug for cancer therapy characterized in that an Axl inhibitor and an immune checkpoint inhibitor (for example, an anti-PD-1 antibody) are administered in...
2019/0099412 ANALGESIC COMPOSITIONS
Analgesic compositions comprise an aminoquinoline together with an opioid, a non-steroidal anti-inflammatory drug (NSAID), a NE/5-HT reuptake inhibitor, or a...
2019/0099411 TYROSINE KINASE INHIBITORS
Disclosed are imidazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure ...
2019/0099410 METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER
Compounds and compositions are described herein for treating post traumatic stress disorder.
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