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| Patent # | Description |
|---|---|
| US-9,663,485 |
Tocopherol and tocopheryl quinone derivatives as correctors of Lysosomal
Storage Disorders The subject invention relates to improved tocopheryl quinone derivatives and tocopherol derivatives having improved pharmacokinetics in vivo that can, in some... |
| US-9,663,484 |
Isoflavonoid compounds and methods for the treatment of cancer Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer... |
| US-9,663,483 |
Furanyl compounds and the use thereof Provided herein are substituted furanyl compounds of formula (I), pharmaceutical compositions comprising the compounds, methods of their preparation, and... |
| US-9,663,482 |
Substituted piperazinyl acetohydrazide procaspase-activating compounds The invention provides compounds and compositions useful for the modulation of certain enzymes. The compounds are of Formula I ##STR00001## The compounds and... |
| US-9,663,481 |
Phenoxy acetic acids and phenyl propionic acids as PPAR.delta. agonists Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or... |
| US-9,663,480 |
BIS-MMF derivatives The present invention relates to novel compounds, e.g. for use as a medicament. In particular, the present invention relates to novel medicaments, preferably in... |
| US-9,663,479 |
.gamma.-aminobutyric acid (GABA) analogues for the treatment of pain and
other disorders A compound of Formula (1) wherein R.sub.1 represents hydrogen, halo, a C1-C4 alkyl group, a C1-C4 alkylhalide group, a C1-C4 alkoxy-C2-C4 alkyl group, a C2-C4... |
| US-9,663,477 |
Synthesis and structure of 3,5-diamino-2,6-di-(tert-butyl-NNO-azoxy)
pyrazine as a critical intermediate in the... The present disclosure relates generally to a critical intermediate in a synthesis of a postulated energetic material, and more specifically relates to a... |
| US-9,663,476 |
Glycine transporter-1 inhibitors The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the... |
| US-9,663,474 |
Heterocyclic substituted 2-amino quinazoline derivatives for the treatment
of viral infections This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use... |
| US-9,663,473 |
Benzimidazolyl-methyl urea derivatives as ALX receptor agonists The present invention relates to benzimidazolyl-methyl urea derivatives of formula (I), ##STR00001## wherein n, D, E, R.sup.1, R.sup.2, R.sup.3, R.sup.4,... |
| US-9,663,472 |
Pyrazole compound The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HT.sub.2C antagonistic action (antidepressive and anxiolytic... |
| US-9,663,471 |
Pyrazole derivatives as modulators of hepatocyte growth factor (scatter
factor) activity The present invention provides compounds having formula (I): ##STR00001## and pharmaceutically acceptable derivatives thereof, wherein R.sup.1, R.sup.2 and B... |
| US-9,663,470 |
Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and
octahydrobenzoquinoline The present invention relates to compounds defined by formula I ##STR00001## wherein the variables R.sup.1, R.sup.2, R.sup.3, R.sup.4, and m are defined as in... |
| US-9,663,469 |
ROR.gamma. modulators Described are ROR.gamma. modulators of the formula (I), or pharmaceutically acceptable salts thereof, wherein all substituents are defined herein. The invention... |
| US-9,663,468 |
2-aminoquinoline-based compounds for potent and selective neuronal nitric
oxide synthase inhibition Various 2-aminoquinoline compounds as can be used, in vivo or in vitro, for selective inhibition of neuronal nitric oxide synthase. |
| US-9,663,467 |
Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12,
IL-23 and/or IFN.alpha. responses Compounds having the following formula (I): or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, and... |
| US-9,663,466 |
Aryl dihydropyridinones and piperidinone MGAT2 inhibitors The present invention provides compounds of Formula (I): ##STR00001## or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the... |
| US-9,663,465 |
Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor
agonists, their methods of preparation... Compounds are provided according to Formula (I) ##STR00001## as well as their enantiomers and their racemics, their acid salts, their hydrates or their... |
| US-9,663,464 |
Carbazole derivatives acting on 5-HT7 receptor The present invention provides a carbazole derivative represented by Formula 1: ##STR00001## wherein X is CH.sub.2 or C(O), Y is selected from... |
| US-9,663,463 |
3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purpose The object of the present invention is to provide a compound having an antagonistic action against .mu.-opioid receptors, which causes less side effects and... |
| US-9,663,462 |
Anti-parasitic methods and compositions utilizing diindolylmethane-related
indoles The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related... |
| US-9,663,461 |
Method for synthesising a mercaptan by adding hydrogen sulfide to an
olefin The invention relates to a method for synthesising a mercaptan from a terminal olefin and hydrogen sulphide which comprises the following consecutive steps:... |
| US-9,663,460 |
Sulfur derivatives as chemokine receptor modulators The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as... |
| US-9,663,459 |
Preparation of surfactants via cross-metathesis The present invention relates to compositions comprising alkene benzenes or alkene benzene sulfonates or alkylbenzenes or alkylbenzene sulfonates; methods for... |
| US-9,663,457 |
Carbamoyl hydrazine derivatives as formyl peptide modulators The present invention relates to carbamoyl hydrazine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as... |
| US-9,663,456 |
Intermediate of tapentadol The present invention relates to novel carbamate intermediate of formula (II), process for its preparation and process for its conversion into ... |
| US-9,663,455 |
Methods for treating attention-deficit/hyperactivity disorder The invention is directed to a method of treating attention-deficit/hyperactivity disorder (ADHD) in a subject, comprising administering a therapeutically... |
| US-9,663,454 |
3-aryl propiolonitrile compounds for thiol labeling The present invention relates to a process for labeling compounds comprising thiol moieties with 3-arylpropiolonitrile compounds, to 3-arylpropiolonitrile... |
| US-9,663,453 |
Metabolites and oximes with vasodilator and hypotensive activity Semi-synthetic oximes derived from metabolites extracted from medicinal plants, Senecio nutans and Xenophyllum poposum, the method of preparation thereof and... |
| US-9,663,452 |
Method for preparing formamidines A method for preparing formamidines of formula (I) in a single step by reducing ureas of formula (II) using silanes of formula (III), according to reaction... |
| US-9,663,451 |
Forms of co-crystals of agomelatine and p toluenesulphonic acid, a process
for their preparation and... The present invention relates to new forms of co-crystals of agomelatine and p-toluenesulphonic acid, to a process for their preparation and to pharmaceutical... |
| US-9,663,450 |
Process for the purification of melphalan A method for the purification and preparation of melphalan that allows to obtain melphalan with purity higher than 99.5% is described. |
| US-9,663,449 |
Lipid containing formulations Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described. |
| US-9,663,448 |
Tri-aryl compounds and compositions comprising the same The present invention relates to a novel class of tri-aryl compounds, compositions comprising the same and processes for the preparation thereof. |
| US-9,663,447 |
Asymmetric butadiene-based charge transport compound, electrophotographic
photoreceptor containing same, and... Provided are an asymmetric butadiene-based charge transporting compound represented by one of Formula (1) and (1') as in claim 1, an electrophotographic... |
| US-9,663,446 |
Process for forming a primary, a secondary or a tertiary amine via a
direct amination reaction Disclosed is a process for preparing a primary, a secondary or a tertiary amine via the direct amination of an alcohol in the presence of a catalyst. The... |
| US-9,663,445 |
Synthesis system, rubber chemical substance for tires, synthetic rubber
for tires, and pneumatic tire The present invention provides a synthesis system that can synthesize aniline and/or styrene efficiently, a synthesis system that can synthesize butadiene... |
| US-9,663,444 |
Heteroatom containing substituted fatty acids Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and... |
| US-9,663,443 |
Process for making tertiary aminoalcohol compounds A process for making a tertiary aminoalcohol compound is disclosed. The process comprises using an excess amount of a carbonyl compound in a condensation step... |
| US-9,663,442 |
Stabilization of household, body-care and food products by using
benzotropolone containing plant extracts... Disclosed is the use of benzotropolone derivatives of formula ##STR00001## wherein R.sub.1, R.sub.2 and R.sub.7 independently from each other are hydrogen;... |
| US-9,663,441 |
Process for cleaning carbon dioxide-containing process gases from the
preparation of vinyl acetate The invention provides processes for cleaning carbon dioxide-containing process gases from the preparation of vinyl acetate after reaction of ethylene with... |
| US-9,663,440 |
Cross metathesis of poly-branched poly-olefins This invention describes processes to make products by cross metathesis of functionalized or non-functionalized olefins with poly-branched poly-olefins such as... |
| US-9,663,439 |
Aildenafil citrate crystal form O, preparation method and use thereof The invention provides a 1-[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d] pyridine-5-group)-4-ethoxy-benzenesulfonyl]-cis-3,5-dimethylpiperazine ... |
| US-9,663,438 |
Process for forming chromium propionate as an agricultural feed additive Chromium propionate, as an animal feed supplement, is created employing chromium carbonate and propionic acid as starting materials. A quantity of chromium... |
| US-9,663,437 |
Production of acetic acid with high conversion rate A process for producing acetic acid comprising the steps of reacting carbon monoxide and at least one of methanol and a methanol derivative in a first reactor... |
| US-9,663,436 |
Method for preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from
1,1,1-trifluoroacetone The invention discloses a method for the preparation of 4-alkoxy-1,1,1-trifluorobut-3-en-2-ones from 1,1,1-trifluoroacetone. |
| US-9,663,435 |
Process for conversion of levulinic acid to ketones A method for generating desired platform chemicals from feedstocks such as cellulosic biomass feedstocks containing levulinic acid by decarboxylating a feed... |
| US-9,663,434 |
Method for hydroformylating an olefin A functionalized nanomaterial having an average particles size of less than 10 nm comprising an iron oxide nanoparticle core and a bis(diarylphosphinomethyl)... |
| US-9,663,433 |
Method of alkylating or acylating an arene A method of alkylating or acylating an arene includes reacting the arene with an organic halide in the presence of an aprotic solvent and a catalyst of formula... |
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