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| Patent # | Description |
|---|---|
| US-9,662,348 |
Compositions for controlling Varroa mites in bees An isolated nucleic acid agent is disclosed comprising a nucleic acid sequence which downregulates expression of a gene product of a Varroa destructor mite.... |
| US-9,662,347 |
Method for inhibiting the induction of cell death by inhibiting the
synthesis or secretion of age-albumin in... The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the... |
| US-9,662,346 |
Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused
by insect stings or noxious weeds or... A method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by an insect or arthropod sting or bite, or a skin contact with a noxious weed or... |
| US-9,662,345 |
Antibiotic composition for inhalation and irrigation An antibiotic composition for the treatment of bacterial infections, especially in the respiratory tract is provided. The antibiotic composition may include a... |
| US-9,662,344 |
Carnitine retention A composition for influencing carnitine retention in biological tissue is disclosed. The composition comprises a carnitine substance and an agent to increase... |
| US-9,662,343 |
Compositions for oral administration of zoledronic acid or related
compounds for treating complex regional pain... Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as... |
| US-9,662,342 |
Formulations of cyclophosphamide liquid concentrate Cyclophosphamide containing compositions preferably in the form of solutions having extended stability are disclosed. The compositions contain cyclophosphamide,... |
| US-9,662,341 |
Multifunctional topical formulation for the treatment of acne vulgaris and
other skin conditions A two-part aqueous composition for treating skin ailments, such as acne vulgaris, includes an acidic part having salicylic acid and an .alpha.-hydroxy acid, and... |
| US-9,662,340 |
Testosterone gel compositions and related methods Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for... |
| US-9,662,339 |
Benzodioxane inhibitors of leukotriene production for combination therapy The present invention relates to a combination comprising compounds of formula (I): ##STR00001## wherein R.sup.1 to R.sup.3, A, X and n are as defined herein,... |
| US-9,662,338 |
Formulations of viloxazine Modified release formulations of viloxazine and methods of administering the same are disclosed. High-drug load formulations of viloxazine are further disclosed. |
| US-9,662,337 |
Bisaryl (thio)morpholine derivatives as S1P modulators Described are compounds that are modulators of the S1P receptors, and pharmaceutical compositions comprising the compounds. Also described are methods of using... |
| US-9,662,336 |
Pyrazolopyrimidine compounds Compounds of formula (I) and salts thereof: ##STR00001## wherein R.sub.1 is n-C.sub.1-6alkyl or C.sub.1-2alkoxyC.sub.1-2alkyl-, R.sub.2 is halo, OH or... |
| US-9,662,335 |
Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B]
pyrimidines as janus kinase inhibitors The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of... |
| US-9,662,334 |
Sildenafil sublingual spray formulations The invention is directed to sublingual spray formulations containing sildenafil. The invention is further directed to methods of treating male sexual... |
| US-9,662,333 |
Tetrahydropyridopyrimidine compound or salt thereof A tetrahydropyridopyrimidine compound represented by formula (I) or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition including the... |
| US-9,662,332 |
Antiviral JAK inhibitors useful in treating or preventing retroviral and
other viral infections Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and ... |
| US-9,662,331 |
3-aryl-2-((arylamino)methyl)quinazolin-4-(3H)-ones The invention relates to novel quinazolinone compounds and their use as inhibitors of PI3 kinases, for example, PI3K.delta., for treating and/or preventing... |
| US-9,662,330 |
Aminopyrimidine derivatives for use as modulators of kinase activity The invention provides novel heterocyclic amine compounds according to Formula (I) and their manufacture and use for the treatment of hyperproliferative... |
| US-9,662,329 |
Use of survivin antagonists in polyomavirus-related disease A method of treating a polyomavirus (+) cancer in which survivin is upregulated in a patient is provided, comprising administering to the patient a... |
| US-9,662,328 |
Targeting human thymidylate kinase induces DNA repair toxicity in
malignant tumor cells The present invention relates to novel TMPK inhibitor and their methods of use. In particular, it relates to novel TMPK inhibitor of Formula (I) and... |
| US-9,662,326 |
Systems for treating an opioid-induced adverse pharmacodynamic response Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient... |
| US-9,662,325 |
Use of opioid antagonists to attenuate endothelial cell proliferation and
migration The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation... |
| US-9,662,324 |
Methods and compositions for treating .beta.-thalassemia and sickle cell
disease Compounds, pharmaceutical compositions, and methods for treating anemia (.beta.-thalassemia anemia or sickle cell anemia. |
| US-9,662,323 |
Compounds having muscarinic receptor antagonist and beta2 adrenergic
receptor agonist activity Compounds of formula I, defined herein, act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating diseases... |
| US-9,662,322 |
Laquinimod for the treatment of relapsing-remitting multiple sclerosis
(RRMS) patients with a high disability... This invention provides a method for treating or for reducing ambulatory deterioration in a human patient diagnosed to be afflicted with relapsing-remitting... |
| US-9,662,321 |
Methods for treating newly diagnosed multiple myeloma with
... Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are... |
| US-9,662,320 |
Antagonists of the cannabinoid receptor CB1 for use in the treatment of
diseases associated with neuronal... The invention relates to antagonists of the cannabinoid receptor CBI for use in the treatment and prevention of diseases associated with neural dendritic... |
| US-9,662,319 |
Methods and materials for assessing responsiveness to lenalidomide,
thalidomide, and/or other thalidomide analogs This document provides methods and materials related to assessing responsiveness to lenalidomide, thalidomide, and/or other IMiDs (structural and functional... |
| US-9,662,318 |
Bitopic muscarinic agonists and antagonists and methods of synthesis and
use thereof Compositions for treating a condition associated with activity of a muscarinic receptor (e.g., one or more of M.sub.1, M.sub.2, M.sub.3, M.sub.4, M.sub.5) and... |
| US-9,662,317 |
Methods of administering tolperisone for therapeutic purposes The present disclosure relates to methods of administering tolperisone to subjects in need thereof. In certain aspects, the present disclosure relates to... |
| US-9,662,316 |
Nitrogen-containing heterocyclic compound The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the... |
| US-9,662,315 |
Ameliorating drug-induced elevations in blood pressure by adjunctive use
of antihypertensive drugs Patients which are treated with stimulants (e.g., CNS stimulants, sympathomimetic amine, or anorectic/anorexigenic), such as patients being treated for... |
| US-9,662,314 |
Compounds and methods for the treatment of muscular disease, and related
screening methods Disclosed are methods of treating a muscle disease and improving normal muscle function by administering a therapeutically effective amount of an isoprenoid... |
| US-9,662,313 |
Compositions and methods for treating amyotrophic lateral sclerosis in
responders A method for treating amyotrophic lateral sclerosis (ALS) in a subject in need thereof comprising administering to said subject an effective amount of... |
| US-9,662,312 |
Method for treating glomerulosclerosis Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are... |
| US-9,662,311 |
Substituted bicyclic compounds as bromodomain inhibitors The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical... |
| US-9,662,310 |
Cyclopropanecarboxylic acid derivative A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein R.sup.1 represents a C1 to C6 alkyl group... |
| US-9,662,309 |
Anti-demodicosis agent The present invention relates to the use of macrocyclic lactones for treating demodicosis, particularly in dogs. |
| US-9,662,307 |
Compositions comprising eicosapentaenoic acid and a hydroxyl compound and
methods of use thereof The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or... |
| US-9,662,306 |
Compositions and methods for diagnosis and treatment of metabolic syndrome Compositions including an odd chain fatty acid, and salts and derivatives thereof, and methods for metabolic syndrome treatment and prophylaxis are provided,... |
| US-9,662,305 |
Use of bucillamine in the treatment of gout Disclosed are pharmaceutical compositions comprising, bucillamine, including bucillamine and allopurinol or colchicine, or pharmaceutically acceptable salts or... |
| US-9,662,304 |
Substituted glutaurine compounds and substituted glutaurine derivatives The present invention is directed to compositions and dietary supplements comprising the following compound ##STR00001## |
| US-9,662,303 |
Composition and method for treating cancer The present invention provides a compound for treating cancer including an isolated form of dibenzyl trisulfide (DTS) provided in an effective amount to act as... |
| US-9,662,302 |
Hydroxytyrosol and oleuropein compositions for induction of DNA damage,
cell death and LSD1 inhibition Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents... |
| US-9,662,301 |
Production of unit dose constructs Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer... |
| US-9,662,300 |
Solid naproxen concentrates and related dosage forms The invention provides a composition consisting essentially of a solid naproxen concentrate, wherein the solid naproxen concentrate comprises (a) a solid... |
| US-9,662,299 |
Yeast cell wall particles for receptor-targeted nanoparticle delivery The present invention generally relates to yeast cell wall microparticles loaded with nanoparticles for receptor-targeted nanoparticle delivery. In particular,... |
| US-9,662,298 |
Wax foamable vehicle and pharmaceutical compositions thereof Unique foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant are provided.... |
| US-9,662,297 |
Production of unit dose constructs Dissolvable unit dose constructs and their method of manufacture are disclosed in which the unit dose constructs are formed of a composition including a polymer... |
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