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Patent # Description
US-9,895,388 Methods and compositions useful for controlling cutaneous mites
The present invention relates to compositions and methods useful for the topical treatment of cutaneous mites comprising spinosyn or a physiologically...
US-9,895,387 Compositions for treating Helicobacter pylori infection
Pharmaceutical compositions for treating infection from Helicobacter pylori. are described, containing, as the active ingredients, polysorbate and an antibiotic...
US-9,895,386 Antibiotic formulations, unit doses, kits, and methods
An aqueous or powder composition includes anti-gram-negative antibiotic or salt thereof being present at an amount ranging from about 100 mg/ml to about 200...
US-9,895,385 Methods for treating pulmonary non-tuberculous mycobacterial infections
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for...
US-9,895,384 Abuse deterrent opioid agonist transdermal compositions and methods for their use
The present disclosure is directed to abuse-resistant transdermal delivery compositions comprising opioid agonists.
US-9,895,383 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as...
US-9,895,382 Di-isopropyl-phosphinoyl-alkanes as topical agents for the treatment of sensory discomfort
The present discovery pertains generally to the field of therapeutic compounds. More specifically the present discovery pertains to certain ...
US-9,895,381 Vitamin D receptor agonists to treat diseases involving CXCL12 activity
Provided herein are methods of treating and preventing pancreatitis, such as pancreatitis induced by glucagon-like peptide (GLP) agonists (such as GLP-1...
US-9,895,380 Methods and pharmaceutical compositions for the treatment of hepatitis B virus infection
The present invention relates to methods and pharmaceutical compositions for the treatment of hepatitis B virus infection. In particular, the present invention...
US-9,895,379 17alpha, 21-dihydroxypregnene esters as antiandrogenic agents
The present application provides 17 and/or 21 esters of 17.alpha.,21-Dihydroxypregna-4,9(11)-diene-3,20-dione and 17.alpha.,21-dihydroxypregna-4-ene-3,20-dione...
US-9,895,378 Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using the same
The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid and a therapeutic agent ...
US-9,895,377 Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
The present invention generally relates to solid forms of tyrosine kinase inhibitors, in particular combinations of tyrosine kinase inhibitors with ...
US-9,895,376 Fused tricyclic compounds as Raf kinase inhibitors
Provided are certain fused tricyclic compounds and salts thereof, compositions thereof, and methods of use therefor.
US-9,895,375 Compositions containing riboflavin and sesamin-class compounds
The present invention relates to a composition containing riboflavin and a sesamin-class compound(s). This composition may incorporate a sesamin-class...
US-9,895,374 Thieno- and pyrrolopyrimidine analogues as anticancer agents and methods of use thereof
The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory...
US-9,895,373 Substituted pyrazolo[3,4-D]pyrimidines and uses thereof
Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers.
US-9,895,372 Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions
The present invention relates to solid pharmaceutical compositions comprising biopterin derivatives as well as methods for obtaining such solid pharmaceutical...
US-9,895,371 Fungicidal agent
The invention relates to a novel fungicidal agent in the form of a salt associate having the structural formula shown. The agent can be used for treating...
US-9,895,370 Pharmaceutical composition for preventing or treating of cirrhosis of liver comprising G protein coupled...
Provided is a pharmaceutical composition for preventing or treating liver fibrosis, comprising a GPR119 ligand as an active ingredient. The composition...
US-9,895,369 Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
The present disclosure relates to stable formulations of receptor tyrosine kinase inhibitors (TKI), e.g., pazopanib; methods of preparation thereof; and use of...
US-9,895,367 Formulation comprising phenylaminopyrimidine derivative as active agent
An oral pharmaceutical formulation containing an effective amount of NRC-AN-019 including its pharmaceutically acceptable salts and polymorphs such as Form I,...
US-9,895,366 Use of a statin compound as topical drug for treating obesity, diabetes, hypertension and hyperlipemia
The invention discloses a use of a statin compound in the preparation of local drugs for improving lipid metabolism and treating obesity, hypertension,...
US-9,895,365 Combination therapy for cancer treatment
Combination therapies for treating cancer comprising administration of a topoisomerase-1 inhibitor and a PARP inhibitor are provided. The topoisomerase-1...
US-9,895,364 Pharmacologically active compounds
The present invention relates to compounds of formula II ##STR00001## wherein X, Y, R.sub.2, R.sub.3, R.sub.4 and Ar are all as defined herein. The compounds...
US-9,895,363 Methods for modulating function of proliferating cell nuclear antigen (PCNA) and treating cancer with...
Pharmaceutical compositions and methods for inhibiting cell growth, modulating function of PCNA, treating prostate cancer, and enhancing PCNA trimer formation...
US-9,895,362 Pharmaceutical composition combining an anticonvulsant and a derivate of nicotinic acid
The combination of gabapentin with lysine clonixinate (CLG) makes it possible to relieve neuropathic pain caused both by diabetic neuropathy and by an injury to...
US-9,895,361 Compositions containing aromatic aldehydes and their use in treatments
Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical...
US-9,895,360 Treatment of sunburn using analgesics and antihistamines
Combination compositions and kits comprising an analgesic and an antihistamine are provided as well as methods of use in treating sunburn.
US-9,895,359 Inhibition of crystal growth of roflumilast
Roflumilast crystals have been shown to increase in size during storage. The size of the roflumilast crystals can affect the bioavailability and efficacy of a...
US-9,895,358 Combination therapies for treatment of spinal muscular atrophy
Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase...
US-9,895,357 Compositions, methods and kits for reducing lipid levels
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of...
US-9,895,356 Methods and compositions for treating anxiety
Methods of treating a TRPC5 mediated disorder in a subject by administering an effective amount of a TRPC5 antagonist, such as a compound disclosed herein, are...
US-9,895,355 Methods of treating androgen receptor-mediated disorders with imidazoline derivatives
Methods for treating androgen receptor-mediated diseases, such as breast cancer, with imidazoline derivatives of formula (I) are provided: ##STR00001##
US-9,895,354 Bilayered calcium sulfate/calcium phosphate space-making composites with multiple drug delivery capabilities
The present invention provides for bilayered composites that provide for sustained drug delivery and support to recovering tissue(s) and areas surrounding, such...
US-9,895,353 Use of L-tryptophan for the treatment of parasomnias
Described is the use of L-tryptophan for treating a subject with parasomnia and associated methods of treating a subject with parasomnia. Optionally, the...
US-9,895,352 Indolinone compounds and uses thereof
Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the...
US-9,895,351 Indomethacin analogs for the treatment of castrate-resistant prostate cancer
Provided are compositions for inhibiting a biological activity of an aldo-keto reductase family 1, member C3 (AKR1C3) polypeptide. In some embodiments, the...
US-9,895,350 Method of dosing and use of soft anticholinergic esters
A method of treating hyperhidrosis in a mammalian subject including: a) providing a composition including a pharmaceutically acceptable vehicle and from about...
US-9,895,349 N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
Inhibitors of HBV replication of Formula (I) ##STR00001## including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X,...
US-9,895,348 Compositions and methods for treating estrogen-related medical disorders
Disclosed herein are methods for treatment of estrogen-related medical disorders. The methods of treatment may comprise administering to a subject in need of...
US-9,895,347 Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
The present invention discloses compounds according to Formula I: ##STR00001## wherein R.sup.1 is as defined herein. The present invention relates to compounds...
US-9,895,346 Applications of substituent benzyloxy group containing ether compounds for preparing antitumor drugs
Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. ...
US-9,895,345 Use of Lappaol F to inhibit tumor cell growth
Provided is a method for inhibiting the growth of tumor cells comprising administering to an individual in need of treatment, a composition comprising a...
US-9,895,344 Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof
Novel compounds and methods related to the activation of the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically...
US-9,895,343 Method for treating tumors with cannabinoids
A method for treating radiotherapy- or chemotherapy-induced cognitive or emotional impairment by topically administering a cannabinoid. Also provided is a...
US-9,895,342 Cannabinoids for use in the treatment of neuropathic pain
The present invention relates to cannabinoids for use in the treatment of neuropathic pain. Preferably the cannabinoids are one or more phytocannabinoids of:...
US-9,895,341 Inflammation and immunity treatments
Therapeutic use of extracts containing proanthocyanidin including treating disorders, e.g., inflammatory disorders, e.g., inflammatory bowel disease, Crohn's...
US-9,895,340 Fluorinated benzofuran derivatives
The invention relates to fluorinated compounds and their use in the field of pathological syndromes of the cardiovascular system. Novel fluorinated benzofuran...
US-9,895,339 Fumigillol compounds and methods of making and using same
The disclosure provides fumagillol type compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of...
US-9,895,338 Cobalt-polypyridyl complex for treatment of cancer, a pharmaceutical composition and a kit comprising it
A method for treating a subject suffering from a cancer, in particular a multidrug-resistant cancer includes administrating a cobalt-polypyridyl complex to the...
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