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Patent # Description
US-9,919,045 Herpes simplex virus vaccine compositions and methods of production and use thereof
Vaccine compositions are disclosed for vaccinating a human or animal against herpes simplex virus infections. Also provided are methods of producing vaccines...
US-9,919,044 Vaccines for diseases caused by viruses of the family of reoviridae
The invention relates to methods for producing a propagation-competent strain of a mutant Reoviridae virus, and to a propagation-competent strain of a mutant...
US-9,919,043 Influenza virus mutants and uses therefor
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein...
US-9,919,042 Influenza virus mutants and uses therefor
Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein...
US-9,919,041 PCV2 immunogenic compositions and methods of producing such compositions
An improved method for recovering the protein expressed by open reading frame 2 from porcine circovirus type 2 is provided. The method generally involves the...
US-9,919,040 Soluble recombinant plasmodium falciparum circumsporozoite protein, use in vaccines, methods of making and uses...
The present invention provides novel nucleotide sequence and other constructs used for expression of novel recombinant P. falciparum circumsporozoite proteins...
US-9,919,039 Partner of SLD five 1 (PSF1)-derived peptide
A Partner of Sld Five 1 (PSF1)-derived peptide that can induce a Cytotoxic T-Cell (CTL) response useful for a specific immunotherapy for cancer patients and a...
US-9,919,038 Compositions comprising angiogenic factors and methods of use thereof
The present invention provides recombinant Listeria strains comprising an angiogenic factor, recombinant polypeptides comprising an angiogenic factor...
US-9,919,037 Immunogenic WT-1 peptides and methods of use thereof
This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a...
US-9,919,036 Identification of tumor-associated antigens for diagnosis and therapy
The invention relates to genetic products the expression of which is associated with cancer diseases. The invention also relates to the therapy and diagnosis of...
US-9,919,035 Pharmaceutical composition comprising bee venom-phospholipase A2 (bv-PLA2) for treating or preventing diseases...
The present invention relates to a pharmaceutical composition for treating or preventing a disease related to abnormal suppression of regulatory T cell activity...
US-9,919,034 Methods of treating and prophylactically protecting mammalian patients infected by viruses classified in...
Viral infections in mammals can be treated and prophylactically prevented by systemic administration of ranpirnase and three other ribonucleases that are highly...
US-9,919,033 Dry growth hormone composition transiently linked to a polymer carrier
The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such...
US-9,919,032 Method for administering a sustained release formulation
The present invention provides pharmaceutical formulations for sustained release when administered at cold temperatures, and methods for delivering a treatment...
US-9,919,031 Use of the insulin-like-growth factor 1 splice variant MGF for the prevention of myocardial damage
The invention relates to the use of a Mechano Growth Factor (MGF) polypeptide or a polynucleotide encoding an MGF polypeptide in the manufacture of a medicament...
US-9,919,030 Follistatin fusion proteins and uses thereof
In certain aspects, the present invention provides methods for dosing a patient with a follistatin antagonist and methods for managing patients treated with a...
US-9,919,029 Methods and pharmaceutical compositions for the treatment of bacterial infections
The present invention relates to methods and pharmaceutical compositions for the treatment of bacterial infections. In particular, the present invention relates...
US-9,919,028 Autoclavable suspensions of cyclosporin A Form 2
Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with...
US-9,919,027 Lipid nanoparticle of polymyxin
A lipid nanoparticle that includes at least one antibiotic from the polymyxin family, a lipid fraction, and one or more surfactants. The lipid nanoparticle is...
US-9,919,026 Vasopressin formulations for use in treatment of hypotension
Provided herein are peptide formulations comprising polymers as stabilizing agents. The peptide formulations can be more stable for prolonged periods of time at...
US-9,919,025 Pharmaceutical formulations of desmopressin
Described herein are orodispersible pharmaceutical dosage forms of desmopressin comprising desmopressin free base or a pharmaceutically acceptable salt thereof,...
US-9,919,024 Formulations of guanylate cyclase C agonists and methods of use
The invention provides low-dose formulations of guanylate cyclase-C ("GCC") agonist peptides and methods for their use. The formulations of the invention can be...
US-9,919,023 Anti-androgen peptides and uses thereof in cancer therapy
The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1):...
US-9,919,022 Use of angiotensin II (AII) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps
Disclosed herein is a therapeutic intervention to prevent, reduce, or treat hemodialysis-associated skeletal muscle cramps by administering All receptor...
US-9,919,021 Brain permeant peptidomimetic beta-secretase 1 inhibitors for the treatment or prophylaxis of neurological...
The present application presents novel peptidomimetic substituted hydroxyethylene compounds, which are inhibitors of beta amyloid cleavage enzyme, capable to...
US-9,919,020 Bioactive compound obtained from oil palm base materials
This disclosure is directed to a novel bioactive compound obtained from oil palm based materials and compositions containing said bioactive compound. The...
US-9,919,019 Use of essential oil of oregano or of rosewood, or constituents thereof, in the cosmetic treatment of keratoses
The present invention concerns various cosmetic uses of compositions comprising an essential oil or one of its constituents, preferably a major constituent, in...
US-9,919,018 Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract
The present disclosure provides compositions and methods for making and using topical compositions comprised of an isotonic, biome-friendly solution containing...
US-9,919,017 Biologically active substance-containing water-solubilizing preparation and method for producing the same
An object of the present invention is to provide a water-solubilizing preparation that is obtained by convenient steps without use of a special apparatus such...
US-9,919,016 Product and method of deploying kale derivatives for anti-cancer effects
The present disclosure describes chemopreventative and/or chemotherapeutic compositions for inducing apoptosis in cancer cells which include kale and methods of...
US-9,919,015 Composition and method for inhibiting herpesviridae infections
The present invention relates to a pharmaceutical composition when used for inhibiting a herpesviridae infection and/or providing relief from a herpesviridae...
US-9,919,014 Reproductive cell maintenance system
Extracts obtained from the genus Hippophae or other plant sources or compositions produced by chemical or molecular biological techniques each having in common...
US-9,919,013 Use of tall oil fatty acid
The present invention relates to use of a tall oil fatty acid in the modulation of microbial population of the animal digestive tract. The invention further...
US-9,919,012 Method of identifying a biologically-active composition from a biofilm
The subject invention provides materials and methods that effectively support innate immunity and/or disperse pathogenic biofilms using readily available,...
US-9,919,011 Method for treating an inflammatory brain disease comprising administering a stem cell-derived exosome
The present invention relates to a composition for treating inflammatory brain diseases, which includes stem cell-derived exosomes as an active ingredient. The...
US-9,919,010 Method for collecting functional cells in vivo with high efficiency
Biologically low invasive vessels are filled with biological factors that have the activity of mobilizing specific functional cells in the body. The vessels are...
US-9,919,009 Production of red blood cells and platelets from stem cells
This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a stem cell into a MEP in culture in the...
US-9,919,008 Method for treating age-related hearing loss (ARHL)
A method for treating age-related hearing loss (ARHL) includes the step administering a composition to the mammal, wherein the composition consists essentially...
US-9,919,007 Dual use oral pharmaceutical composition tablets of sulfate salts and methods of use thereof
The present invention is generally directed to an oral pharmaceutical tablet composition comprising a sulfate salt, for example, sodium sulfate, wherein the...
US-9,919,006 Compositions and methods for treating hyperkalemia
The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of...
US-9,919,005 Immune-modifying nanoparticles for the treatment of inflammatory diseases
The current invention involves the administration of negatively charged particles, such as polystyrene, PLGA, or diamond particles, to subjects to ameliorate...
US-9,919,004 Polymer-based dialysate
Embodiments described herein provide a dialysate comprising a polyglycerol. The polyglycerol may be of a molecular weight between about 0.15 kDa and about 60...
US-9,919,003 Nicotinamide mononucleotide derivatives and their uses
The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing...
US-9,919,002 Methods and constructs for compound delivery
A construct for selectively delivering a compound of interest to a cell, includes (a) a bioresorbable polymer shell; (b) a nucleic acid duplex contained in said...
US-9,919,001 Drug carrier having L-DNA nanocage structure
The present invention relates to a drug carrier having L-DNA nanocage structure prepared by using L-DNA, the mirror form of natural DNA, as a backbone. The drug...
US-9,919,000 Altering cancer cellular functions through proton mopping
Proton mopping is a new anti-cancer therapeutic approach that disrupts cancer's immunologic balance. It results in the alteration of the pHi/pHe ratio...
US-9,918,999 Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis
Method for preparing a medical solution, comprising the steps of a) providing a solution comprising one or more acetylated or deacetylated amino sugar/sugars in...
US-9,918,998 Pharmaceutical tetracycline composition for dermatological use
Provided herein is a topical composition and related methods for making and using the composition. In a first aspect, the topical composition comprises...
US-9,918,997 Compositions and methods for the treatment of neurodegenerative and other diseases
In one embodiment, the present application discloses methods of treating diseases and disorders with sulfasalazine and pharmaceutical formulations of...
US-9,918,996 Methods of using qiapine
Methods of treating renal failure are described. In particular, methods of treating renal failure by administration of pharmaceutical composition including a...
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