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Patent # Description
US-9,963,748 Methods and compositions for classifying DLBCL
Provided herein are methods and compositions to classify DLBCL subtypes using quantitative RT-PCR.
US-9,963,747 Methods for the identification, assessment, and treatment of patients with cancer therapy
The present invention is directed to the identification of predictive markers that can be used to determine whether patients with cancer are clinically...
US-9,963,746 Composition or kit for making a prognosis of liver cancer, and method for making a prognosis of liver cancer
The present disclosure provides a marker for predicting prognosis of liver cancer, a composition or kit for predicting prognosis of liver cancer, preferably, a...
US-9,963,745 Hematological disorder diagnosis by 3D q-FISH
Provided are methods for prognosing a clinical outcome in a subject with a hematological disorder comprising determining a 3D telomeres organization signature...
US-9,963,744 Composition for promoting chondrocyte differentiation or treating cartilage diseases, containing KLF10...
The present invention relates to a Krueppel-like factor 10 (KLF10) gene expression inhibitor promoting cartilage differentiation, and more specifically, to: a...
US-9,963,743 Single nucleotide polymorphisms (SNPs) in genes accociated with inflammatory diseases
The present disclosure describes the identification of single nucleotide polymorphisms (SNPs) in inflammatory diseases and uses thereof, and methods of...
US-9,963,742 KIR3DL1 allele classification kit and method
Disclosed herein are single nucleotide polymorphisms (SNPs) characteristic of functional subgroups of KIR3DL1. Also disclosed herein are methods for classifying...
US-9,963,741 Screening methods for transfusion related acute lung injury (TRALI)
The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence....
US-9,963,740 Method and device for marking articles
Provided are a method and device for marking an article for security, tracking or authentication. The method includes depositing a solution comprising a nucleic...
US-9,963,739 Polymerase chain reaction systems
In one embodiment, a polymerase chain reaction (PCR) system includes a mixture chamber, a denature chamber, an annealing chamber, an extension chamber, and a...
US-9,963,738 Detection of nucleic acids
The present invention provides modified oligonucleotides and methods for their use in the detection of nucleic acids. The oligonucleotides and methods find...
US-9,963,737 Dual probe assay for the detection of heterogeneous amplicon populations
The present invention relates to a method for amplifying and detecting a target nucleic acid in a sample, said target nucleic comprising subgroups with sequence...
US-9,963,736 Using repetitive sequences for DNA quality assessments
The present disclosure provides methods, arrays and kits for assessing the quality of genomic DNA samples, especially those obtained from formalin-fixed...
US-9,963,735 Selective 5' ligation tagging of RNA
The present invention provides novel compositions, kits and methods employing RNA 5' polyphosphatases, RNA 5' monophosphatases, capping enzymes, decapping...
US-9,963,734 Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl...
Provided is a compound that comprises the structure: ##STR00001## where SIG is a signaling molecule and R.sup.3 is a formyl, a succinyl, a methyl succinyl, or...
US-9,963,733 Devices, systems and methods for detecting viable infectious agents in a fluid sample
Various devices, systems and methods for detecting a susceptibility of an infectious agent to an anti-infective are described herein. A method comprises...
US-9,963,732 Thermochromic sensing devices, systems, and methods
One or more live substances is cultured at a plurality of test locations of a test vessel. The test locations include a thermochromic material and one or more...
US-9,963,731 Method for producing carotenoids each having 50 carbon atoms
The present invention provides a method of producing a carotenoid having 50 carbon atoms which comprises culturing, in a medium, a cell transformed with a...
US-9,963,730 Processing biomass
Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a...
US-9,963,729 Diversification of human milk oligosaccharides (HMOs) or precursors thereof
A method of diversification of human milk oligosaccharides (HMOs) or precursors thereof, compounds obtainable by the method, and uses and compositions involving...
US-9,963,728 Method of manufacturing filter aid
A method of producing a filter aid includes: (A) obtaining a pretreated biomass by pulverization treatment and/or thermochemical treatment of a ...
US-9,963,727 Production of products from biomass
The processes disclosed herein include saccharifying cellulosic and/or lignocellulosic biomass and fermenting the sugars to produce a sugar alcohol.
US-9,963,726 Fiber-containing carbohydrate composition
A food product comprises an oligosaccharide composition that is digestion resistant or slowly digestible. The oligosaccharide composition can be produced by a...
US-9,963,725 Process for fractionation of oligosaccharides from agri-waste
The present invention provides a continuous and cost effective chemo-enzymatic process for fractionation of holocellulose, obtained from agri-waste, into...
US-9,963,724 Method for producing 5-aminolevulinic acid or salt thereof
Provided is a method for producing 5-aminolevulinic acid or a salt thereof at a high yield using 5-aminolevulinic acid-producing microorganisms. The method for...
US-9,963,723 Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
US-9,963,722 Strain secreting fatty acids by phospholipase and method for producing fatty acids using it
A bacterial strain secreting fatty acids, the strain inducing fatty acids to be extracellularly secreted by using phospholipase expressed in the periplasmic...
US-9,963,721 Method of screening gene for 1,4-BDO production
Provided is a screening method of discovering genes capable of increasing 1,4-BDO production on the basis of proteomics data. Over-expression of proteins...
US-9,963,720 Alkane oxidation by modified hydroxylases
This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing...
US-9,963,719 Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by...
US-9,963,718 LCMV-GP-VSV-pseudotyped vectors and tumor-infiltrating virus-producing cells for the therapy of tumors
The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of...
US-9,963,717 Method for expression of small RNA molecules within a cell
The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to...
US-9,963,716 Chimaeric surrogate light chains (SLC) comprising human VpreB
The present invention relates inter alia to improvements in the production of chimaeric antibodies in non-human transgenic vertebrates such as mice and rats...
US-9,963,715 Methods and compositions for treatment of a genetic condition
Disclosed herein are nucleases and methods of using these nucleases for alteration of a globin gene and generation of cells.
US-9,963,714 Cotton variety 16R247NRB2XF
The invention relates to the novel cotton variety designated 16R247NRB2XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the...
US-9,963,713 Brassica plants resistant to clubroot
The present invention relates to a Brassica plant, in particular a Brassica oleracea plant carrying a genetic determinant that may comprise QTLI and/or QTL2...
US-9,963,712 Gene IbENOD93 and transgenic plants using the same
The present invention relates to a novel gene, IbENOD93, and transgenic plants using the same. More specifically, the present invention provides an IbENOD93...
US-9,963,711 FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in...
US-9,963,710 Methods and compositions for identifying and enriching for cells comprising site specific genomic modifications
The present invention relates to methods and compositions for modifying a target site in the genome of a plant cell. Such modifications include integration of a...
US-9,963,709 Transformable Rhodobacter strains, method for producing transformable Rhodobacter strains
The invention provides an organism for expressing foreign DNA, the organism engineered to accept standard DNA carriers. The genome of the organism codes for...
US-9,963,708 Recombinant vector for foreign gene expression without biological circuit interference of host cell and uses...
A recombinant vector enables independent expression of a foreign gene without interfering with a biological circuit of a host cell. A gene encoding a guanylyl...
US-9,963,707 Multiprotein expression cassettes
Methods for expressing multiple proteins by constructing transformation vectors that include multiprotein expression cassettes and transforming hosts with...
US-9,963,706 Methods and compositions for backscattering interferometry
The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions,...
US-9,963,705 DNMT inhibitors
RNA molecules inhibiting a DNMT and methods and compositions incorporating or generating the RNA molecules are described.
US-9,963,704 Modulating the interaction between ZO-2/TJP2 and a Snail zinc finger transcription factor family member
There is provided a method of identifying candidate agents capable of modulating interaction between a first polypeptide and a second polypeptide, wherein the...
US-9,963,703 Compositions and methods for treating pancreatic cancer
Provided herein are composition for sensitizing tumors to anti-tumor therapies. The compositions include antisense oligonucleotides against TGF.beta.2, wherein...
US-9,963,702 RNA interference in dermal and fibrotic indications
The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and...
US-9,963,701 Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising HRP-3 inhibitor
The present invention relates to a pharmaceutical composition for treating a radiation- or drug-resistant cancer, containing an agent capable of inhibiting the...
US-9,963,700 GNAQ targeted dsRNA compositions and methods for inhibiting expression
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a G-alpha q subunit (GNAQ) of a heterotrimeric G gene, and methods of using the...
US-9,963,699 Methods for modulating C9ORF72 expression
Disclosed herein are methods for reducing expression of C90RF72 mRNA and protein in an animal with C90RF72 specific inhibitors. Such methods are useful to...
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