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Patent # Description
US-9,993,468 Pharmaceutical composition for topical application
A pharmaceutical composition comprises a solution having a pH of from 5 to 7.5, including loratadine and/or desloratadine. The composition is suitable for...
US-9,993,467 Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione
Pharmaceutical compositions and single unit dosage forms of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, or a pharmaceutically acceptable...
US-9,993,466 Donepezil transdermal delivery system
A transdermal delivery system for systemic delivery of donepezil is described, where the system comprises an adhesive matrix drug reservoir layer comprised of a...
US-9,993,465 2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof
Disclosed are heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. The compounds are useful for treating a mammal suffering from any...
US-9,993,464 Otamixaban formulations with improved stability
The invention relates to a pharmaceutical composition comprising methyl (2R.3R)-2-{3-[amino(imino)methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzo- ...
US-9,993,463 Use of maleimide derivatives for preventing and treating cancer
The present invention is related to a compound of formula (I) a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, a metabolite...
US-9,993,462 Hydantoin derivative-containing pharmaceutical composition
The present invention provides pharmaceutical compositions for inducing bone and/or cartilage anabolism, which comprises as an active ingredient a compound...
US-9,993,461 Method for treating disorders associated with glomerular function
Methods of administering and pharmaceutical compositions of a biphenyl sulfonamide compound which is a dual angiotensin and endothelin receptor antagonist are...
US-9,993,460 Compositions to improve the therapeutic benefit of bisantrene and analogs and derivatives thereof
The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal...
US-9,993,459 Selective HDAC6 inhibitors and uses thereof
The present invention relates to selective Histone deacetylase 6 (HDAC6) inhibitors and compositions containing the same. Methods of treating diseases and...
US-9,993,458 Method of treating MYC-amplified tumors with RNA-polymerase II inhibitors
Systems and methods for determining whether a cancer patient may respond to inhibition of RNA polymerase II as a treatment for the patient are provided....
US-9,993,457 Method of improving visual processing, visual acuity, or both by administering compositions comprising...
Methods for improving the visual processing of a healthy infant by administering a composition comprising RRR-alpha-tocopherol and a carotenoid to the infant...
US-9,993,456 Preparation and use of a composition for prevention and mitigation of the effects of radiation
Plant extracts, compositions, pharmaceutical compositions and methods of making and using the same are provided herein. The compositions comprise ...
US-9,993,455 Method of mitigating long term detrimental effects of exposure to medical imaging ionizing radiation by...
Mitigation of long term detrimental effects of exposure to medical imaging ionizing radiation by administration of an amount of genistein in the form of a...
US-9,993,454 Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced Ostwald ripening
The present invention belongs to the fields of pharmacology, medicine and medicinal chemistry. The present invention provides novel pharmaceutical compositions...
US-9,993,453 Dosage forms and therapeutic uses L-4-chlorokynurenine
Compositions of L-4-chlorokynurenine are provided, as are methods for the treatment of neurological dysfunction.
US-9,993,452 Compositions and methods for treatment of inflammation
The present invention is directed to novel anti-inflammatory immunomodulators including creatinine or a creatinine salt, for example, creatinine hydrochloride....
US-9,993,451 Continuous administration of dopa decarboxylase inhibitors and compositions for same
Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or...
US-9,993,450 Dosage forms and therapeutic uses of L-4-chlorokynurenine
Compositions of L-4-chlorokynurenine are provided, as are methods for the treatment of neurological dysfunction.
US-9,993,449 (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, and related compounds as GABA...
Cyclopentene carboxylic acid-related compounds as GABA-AT inhibitors for treatment of various addictions, disorders and disease states.
US-9,993,448 Bolus dose of hydroxycitric acid with glycerol
A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active...
US-9,993,447 Systems and methods for increasing agmatine cellular uptake by oral administration
Formulations of hydrosoluble stable organic salts including, but not limited to, agmatine orotate, agmatine di-hydrochloride, agmatine phosphate, buffered...
US-9,993,446 Biguanide derivative, a preparation method thereof, and a pharmaceutical composition containing the biguanide...
A biguanide derivative compound with N1-N5 substitution, which is represented by Formula 1, or a pharmaceutically acceptable salt thereof a method of preparing...
US-9,993,445 Oral solution comprising atomoxetine hydrochloride and methods thereof
Disclosed herein is an oral pharmaceutical composition in the form of an aqueous solution of atomoxetine as an active ingredient. The aqueous solution of...
US-9,993,444 Use of beta-adrenergic inverse agonists for smoking cessation
The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus...
US-9,993,443 Dosage forms and related therapies
This invention is directed in part to novel doses, dosage formulations, and routes of administration of such doses and dose formulations, said dose and dose...
US-9,993,442 Method for the treatment or prevention of lower urinary tract symptoms
This invention concerns a method for treatment or prevention of lower urinary tract symptoms with or without pelvic pain in an individual, said method...
US-9,993,441 Controlled release matrix barrier structure for subcutaneous medical devices
A biocompatible polymeric controlled release matrix barrier structure for delivery of one or more bioactive agents from an implantable medical device is...
US-9,993,440 Enzyme responsive nanocapsules for protein delivery
The invention provides methods of making and using compositions comprising a polymer shell designed to deliver polypeptides to selected environments. In...
US-9,993,439 Mucoadhesive nanoparticle delivery system
The present disclosure relates generally to a mucoadhesive nanoparticle delivery system. The nanoparticles are formed from amphiphilic macromolecules conjugated...
US-9,993,438 Drug delivery system for administration of poorly water soluble pharmaceutically active substances
This invention relates to a drug delivery system for administration of poorly water soluble pharmaceutically active substance, a pharmaceutical composition...
US-9,993,437 Mesoporous silica nanoparticles for biomedical applications
A submicron structure includes a silica body defining a plurality of pores that are suitable to receive molecules therein, the silica body further defining an...
US-9,993,436 Porous hollow fiber anti-solvent crystallization-based continuous method of polymer coating on submicron and...
Using porous hollow fiber membranes, systems/methods for continuously synthesizing polymer-coated particles by anti-solvent crystallization are provided. The...
US-9,993,435 Colonic drug delivery formulation
A delayed release coating comprising a mixture of a first material selected from starch; amylose; amylopectin; chitosan; chondroitin sulfate; cyclodextrin;...
US-9,993,434 Calcium carbonate granulation
Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate...
US-9,993,433 Manufacturing of active-free granules and tablets comprising the same
The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.
US-9,993,432 Pharmaceutical dosage form comprising nifedipine or nisoldipine and an angiotensin II antagonist and/or a diuretic
The present invention relates to a pharmaceutical dosage form comprising an active ingredient combination of nifedipine or nisoldipine and at least one...
US-9,993,431 Diversion-resistant microgranules and microtablets
The invention relates to the use of an oral dosage form based on microgranules and/or microtablets to reduce the abusive use of at least one active principle...
US-9,993,430 Tablet formulation comprising semaglutide and a delivery agent
The present invention relates to solid compositions comprising a GLP-1 peptide and a delivery agent, such as SNAC, as well as uses thereof.
US-9,993,429 Composition and methods for the treatment of peripheral nerve injury
Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the...
US-9,993,428 Gastroretentive drug formulation and delivery systems and their method of preparation using functionalized...
An instantly floating gastroretentive drug formulation comprising at least one functionalized natural and/or synthetic calcium carbonate-comprising mineral and...
US-9,993,427 Liposome formulation and manufacture
The present invention relates to a liposomal formulation containing a therapeutic agent and a process for producing the formulation. The liposomal formulation...
US-9,993,426 Bisacodyl compositions and delivery apparatus
A pharmaceutical composition comprising bisacodyl [4,4'-(pyridine-2-ylmethylene)bis(4,1-phenylene) diacetate], a solvent, a buffer, and a polymer, methods and...
US-9,993,425 Compositions for intranasal delivery of human insulin and uses thereof
What is described is a pharmaceutical formulation for intranasal delivery of insulin to a patient, comprising an aqueous mixture of human insulin, a...
US-9,993,424 Intravaginal matrix drug delivery devices
The present invention relates to a process for the preparation of an intravaginal matrix drug delivery device. The process comprises the steps of combining at...
US-9,993,423 Microneedle deposition method
The present invention provides a microneedle array which holds a drug only in the microneedle portions, and a method of manufacturing the same. The microneedle...
US-9,993,422 Immediate release, abuse deterrent pharmaceutical compositions
The present disclosure provides pharmaceutical compositions and processes for making solid dosage form pharmaceutical compositions that provide immediate...
US-9,993,421 Method for treating deleterious effects arising from tattoos
A method of treating a medical condition resulting from a tattoo has the steps of cleaning at least one surface of the tattoo; preparing a plurality of needles...
US-9,993,420 Method of treating hair with a concentrated conditioner
A method of treating the hair including providing a pre-aerated concentrated hair care composition. The pre-aerated concentrated hair care composition includes...
US-9,993,419 Method of treating hair with a concentrated conditioner
A method of treating the hair including providing a concentrated hair care composition in an aerosol foam dispenser. The concentrated hair care composition...
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