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Patent # Description
US-1,005,8541 Multisubstituted aromatic compounds as serine protease inhibitors
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or...
US-1,005,8540 2-amino-5,5-difluoro-6-(fluoromethyl)-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
The present invention is directed to compounds of Formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to...
US-1,005,8539 Pharmaceutical compositions containing a PDE4 inhibitor and a PI3 delta or dual PI3 delta-gamma kinase inhibitor
This present invention relates to a method of treating a autoimmune, respiratory and/or inflammatory disease or condition (e.g., psoriasis, rheumatoid...
US-1,005,8538 Compositions comprising substituted benzofuroquinolizine and .alpha..sub.2-adrenergic agonists
The present invention relates to compositions for facilitating absorption and distribution of .alpha..sub.2-adrenergic agonists, where said composition...
US-1,005,8536 Pharmaceutical composition containing mirabegron
To provide: (1) a modified release liquid (suspension) containing mirabegron, (2) a ready-to-suspend pharmaceutical composition containing mirabegron, and (3) a...
US-1,005,8535 Nuclear transport modulators and uses thereof
The present invention relates to compounds of formula I: ##STR00001## and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the...
US-1,005,8534 Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
The present invention relates to compounds of formula I: ##STR00001## in which n, m, X, Y.sub.1, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined in...
US-1,005,8533 Pharmaceutical composition containing Ginkgolide B and Xa factor inhibitor, preparation method thereof and use...
A pharmaceutical composition containing ginkgolide B and an Xa factor inhibitor xaban, a preparation method and use of the pharmaceutical composition, wherein...
US-1,005,8532 Methods of preventing progression to type 2 diabetes mellitus
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and...
US-1,005,8531 Dosage delivery film
A dosage delivery film composition containing a botanical drug substance formable into a bioerodible dosage delivery film, the dosage delivery film composition...
US-1,005,8530 Combination therapies for the treatment of Alzheimer's disease and related disorders
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
US-1,005,8529 Nutraceutical composition for PDE4 inhibition, enhanced dopamine metabolism and long term potentiation
A nootropic combination for increasing cognitive functioning. The combination includes a phosphodiesterase 4 inhibitor and a cyclic adenosine monophosphate...
US-1,005,8528 Compositions and methods for treating non-alcoholic steatohepatitis
Compositions and method are disclosed comprising ethyl icosapentate for use in treatment of non-alcoholic steatohepatis (NASH).
US-1,005,8527 Composition containing monoacetyldiacylglycerol compound as active ingredient for inhibiting blood cancer or...
The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis,...
US-1,005,8526 Compositions containing pheromones for treating behavioural or medical problems linked to the stress of...
The invention relates to a composition containing pheromones comprising a carrier solvent, and to the use thereof for preventing and/or treating the behavioral...
US-1,005,8525 Application of chlorogenic acid in preparing medicines for treating lupus erythematosus
The present invention provides an application of chlorogenic acid in preparing medicines for treating lupus erythematosus. The chlorogenic acid can improve an...
US-1,005,8524 Methods for improving joint function
The present technology provides methods for improving joint function in a subject in need thereof. The methods include administering to the subject an effective...
US-1,005,8523 Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of cancer and...
Disclosed are novel methods for the therapeutic treatment of cancer and angiogenesis. The enzyme Ape1/Ref-1, via its redox function, enhances the DNA binding...
US-1,005,8522 Oxidative retinal diseases
Some aspects of the invention provide for a method of treating Wet and/or Dry Age-related Macular Degeneration, Retinitis Pigmentosa, Diabetic Retinopathy,...
US-1,005,8521 Omega-3 pentaenoic acid compositions and methods of use
Orally administrable composition comprising fatty acids, wherein at least 50% by weight of the fatty acids comprise omega-3-fatty acids, salts or derivatives...
US-1,005,8520 Compositions and methods for treating alzheimer's disease and dementia
The present invention relates to a method of treating, preventing, or delaying the onset of Alzheimer's disease and/or dementia in mammals. More particularly,...
US-1,005,8519 Treatment of pain with topical diclofenac
The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of...
US-1,005,8518 Bupropion as a modulator of drug activity
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
US-1,005,8517 Methods of treating acanthamoeba infection using apocynin
Described herein are methods of treating an Acanthamoeba infection in a subject in need thereof by administering an amount of apocynin.
US-1,005,8516 Design, synthesis and methods of use of acyclic fleximer nucleoside analogues having anti-coronavirus activity
The present invention is directed to compounds, methods and compositions for treating or preventing viral infections using nucleosides analogs. Specifically,...
US-1,005,8515 Cannabidiol for treatment of severe and refractory graft-versus-host disease
The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol...
US-1,005,8514 Silk-based scaffold platform for engineering tissue constructs
The inventions provided herein relate to silk-based scaffolds and methods of producing the same, which can be used for a range of tissue engineering...
US-1,005,8513 Delivery system for active agents
A delivery system containing an active agent within a polymeric material formed from a thermoplastic composition is provided. Through selective control over the...
US-1,005,8512 Rumen protected glucose and method of preparation
The present disclosure provides a preparation method of rumen protected glucose, comprising the following steps: (1) preparing glucose into a pellet and drying;...
US-1,005,8511 Nanocrystals, compositions, and methods that aid particle transport in mucus
Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making...
US-1,005,8510 Pharmaceutical composition of aprepitant
Disclosed herein a pharmaceutical composition comprising aprepitant a pharmaceutically acceptable salt thereof; at least one hydrocarbon derivative selected...
US-1,005,8509 Alkyl cellulose for use in tableting and solid preparation comprising same
Provided are an alkyl cellulose excellent in formability when added even in a small amount and not causing marked delay in disintegration; a solid preparation...
US-1,005,8508 Direct compression excipient based on lactose, cellulose and starch
The present invention relates to compositions comprising at least one lactose component, at least one cellulose component and at least one starch component, its...
US-1,005,8507 Compositions for delivery of drug combinations
Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic...
US-1,005,8506 Tunable anti-microbial loaded hydrogels
A tunable antimicrobial-loaded hydrogel formulation has a mechanical strength can be altered by changing the salt composition. The hydrogel formulation is...
US-1,005,8505 Transscleral drug delivery
Magnetic drug-loaded polymeric particles are used in a transscleral drug delivery method. In the synthesis process of the aforementioned magnetic drug-loaded...
US-1,005,8504 Methods for the preparation of injectable depot compositions
Injectable depot compositions, comprising a biocompatible polymer which is a polymer or copolymer based on lactic acid and/or lactic acid plus glycolic acid...
US-1,005,8503 Daily face cream
This invention is a natural face cream/lotion that exploits the benefits of Dead Sea salt for helping moisturize the skin of a human face. The lotion consists...
US-1,005,8502 Nail polish compositions
Compositions including polycarbodiimide together with latex compounds to enhance the quality of the keratinous substrates. The present invention relates to a...
US-1,005,8501 Mascara composition and method
Cationically-charged particulates and compositions containing the cationically-charged particulates for application to keratinous materials are provided....
US-1,005,8500 Method for enhanced photoepilation based on metallic nano-complexes
The present invention relates to a composition for topical application on skin for photoepilation comprising nanocomplexes which comprise a nanoparticle...
US-1,005,8499 Sterilized composition comprising at least one hyaluronic acid and magnesium ascorbyl phosphate
The invention relates to a sterilized composition comprising at least one hyaluronic acid or biologically acceptable salt thereof, alone or in a mixture, and...
US-1,005,8498 Composition and method of producing personal care compositions with improved deposition properties
The presently disclosed and/or claimed inventive concept(s) relates generally to the use of nonionic hydrophobically modified polysaccharides in personal care...
US-1,005,8497 Oral hygiene products and method of using the same
A chewing gum for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an...
US-1,005,8496 Thermosensitive ionic composite, preparing method thereof, and biodegradable composition containing the same
A thermosensitive ionic composite having a multistage phase transition characteristic, a method for preparing the thermosensitive ionic composite, and a...
US-1,005,8495 Method of making a skin care product
A method of making a skin care product that includes a skin care composition containing a skin care active with a diamagnetic susceptibility of between about...
US-1,005,8494 Compositions for altering the color of hair
The disclosure relates to compositions for treating keratinous substrates, such as the hair, comprising monoethanolamine and at least one carboxylic acid, as...
US-1,005,8493 Oral care compositions and methods of use
This invention relates to oral care compositions comprising arginine, zinc citrate and zinc oxide, and an orally acceptable carrier, as well as to methods of...
US-1,005,8492 Oral care composition comprising bleaching agent
The disclosed invention relates to a composition for delivery of a bleaching agent to an oral cavity. The composition is stable to environmental storage...
US-1,005,8491 Stable formaldehyde-free microcapsules
The present invention relates to water-dispersible core-shell microcapsules essentially free of formaldehyde. In particular it concerns core-shell microcapsules...
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