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Patent # Description
US-1,007,6536 Oligonucleotide analogues targeting human LMNA
Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin.
US-1,007,6535 Use of CPG oligonucleotides co-formulated with an antibiotic to accelerate wound healing
Pharmaceutical compositions are provided that include an antibiotics, but that include ingredients that counteract the effect of that antibiotic on wound...
US-1,007,6534 Effective treatment of ovarian cancer using triciribine and related compounds
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat ovarian cancer by one or a combination of...
US-1,007,6533 Acyclic nucleoside phosphonate diesters
The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and...
US-1,007,6532 Acyclic nucleoside phosphonate diesters
The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and...
US-1,007,6531 Dialysis solution, use of a dialysis solution and chemical compound
The present invention relates to a dialysis solution having at least one osmotic agent, wherein the osmotic agent is starch propylphosphonate.
US-1,007,6530 Lipid compositions with high DHA content
The invention provides lipid compositions comprising phospholipids having a high docosahexaenoic acid (DHA) content, which compositions are preferably extracted...
US-1,007,6529 Small molecule inhibitors of influenza A RNA-dependent RNA polymerase
Compositions, compounds, and methods with significant antiviral effect against RNA viruses and especially orthomyxoviruses are contemplated, and target the...
US-1,007,6528 System and method for diagnosis and treatment
This invention relates the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the treating or preventing treatment resistant prostate...
US-1,007,6527 Standardized extract and its use in the manufacture of a medicament
The present invention refers to a medicament which activates gastrointestinal movement. The medicament consists essentially of Cucurbitacin D and one or more...
US-1,007,6526 Ocular implant made by a double extrusion process
The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants...
US-1,007,6525 Sex steroid precursors alone or in combination with selective estrogen receptor modulators for the prevention...
Novel methods for treating or reducing the likelihood of acquiring vaginal dysfunctions, more particularly vaginal dryness and dyspareunia, leading to sexual...
US-1,007,6524 Pharmaceutical composition of fused aminodihydrothiazine derivative
The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): ##STR00001## or ...
US-1,007,6523 HSPC-sparing treatments for RB-positive abnormal cellular proliferation
This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular...
US-1,007,6522 Systems and methods for treating bacterial infection
Therapeutic methods, kits, dosing regimens and uses as medicament are provided, for example, for the treatment of bacterial infection. The therapeutic methods...
US-1,007,6521 DNA-PK inhibitors
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said...
US-1,007,6520 Use of tyrosine kinase inhibitor in cancer treatment
The present invention provides methods for reducing apoptosis of non-cancerous cells during a cancer treatment and beneficial effects associated with reducing...
US-1,007,6519 Substituted pyridazines as skeletal muscle modulators
Provided are compounds of Formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6,...
US-1,007,6518 Method of treating a brain tumor
Disclosed herein are methods of treating a brain tumor by administering Plinabulin. Some embodiments relate to treatment of glioblastoma multiforme by...
US-1,007,6517 Methods and pharmaceutical compositions for the treatment of fibrosis
The present invention relates to methods and pharmaceutical compositions for the treatment of fibrosis. In particular, the present invention relates to a method...
US-1,007,6516 Methods of manufacturing oral dosage forms
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a...
US-1,007,6515 Ophthalmic Composition
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment...
US-1,007,6514 Methods of treating fabry disease in patients having the G9331A mutation in the GLA gene
Provided are methods of treating a patient diagnosed with Fabry disease and methods of enhancing .alpha.-galactosidase A in a patient diagnosed with or...
US-1,007,6513 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) ...
A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid),...
US-1,007,6512 Treatment of hepatitis delta virus infection
Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with...
US-1,007,6511 Bisamide derivative of dicarboxylic acid as an agent for stimulating tissue regeneration and recovery of...
The invention relates to the field of medicine and concerns an agent that stimulates tissue regeneration and the recovery of diminished tissue and organ...
US-1,007,6510 Pharmaceutical composition comprising ...
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient, which is selected from ...
US-1,007,6509 Nested particles and the use thereof for coordinated delvery of active agents
Methods and compositions regarding nested nanoparticles comprising polymer nanoparticles encased in a cyclodextrin shell to facilitate sequence-specific drug...
US-1,007,6508 Pharmaceutical compositions for inhibiting antibiotic-resistant microorganisms and uses thereof
This invention provides an antibiotic drug for inhibiting drug-resistant microorganisms. The antibiotic drug comprises Fmoc-Ala-OPfp, and not only has...
US-1,007,6507 Compositions and methods for modulating metabolic pathways
Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or...
US-1,007,6506 Baclofen formulations and methods for making same
Methods for preparing sterilized baclofen solutions include adjusting the pH to below a desired pH, and steam sterilizing the solution with adjusted pH, which...
US-1,007,6505 Inhalation formulations of Treprostinil
The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or...
US-1,007,6504 Glucagon antagonists
Provided herein are compounds, including enantiomerically pure forms thereof, and pharmaceutically acceptable salts or co-crystals and prodrugs thereof which...
US-1,007,6503 Dosage of dasotraline and method for treatment of ADHD
Dosage forms and treatment regimens employing dasotraline for treating Attention Deficit Hyperactivity Disorder (ADHD) are disclosed. The compositions described...
US-1,007,6502 Transdermal therapeutic system for administering rivastigmine or derivatives thereof
The present invention relates to a transdermal therapeutic system for administering an active substance through the skin, comprising: a) a cover layer, b) a...
US-1,007,6501 Use of polymeric excipients for lyophilization or freezing of particles
Provided herein are use of polymeric excipients, specifically polyvinyl alcohols, optionally in conjunction with sugars, as cryoprotectants to prevent...
US-1,007,6500 Floating gastric retentive dosage form
An elongate dosage form of generally cylindrical shape having two opposing ends, the dosage form being buoyant in gastric fluid, wherein the dosage form is...
US-1,007,6499 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-1,007,6498 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-1,007,6497 Pharmaceutical formulation containing gelling agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
US-1,007,6496 Engineering of polymer-stabilized nanoparticles for drugs with Log P values below 6 by controlled antisolvent...
The present invention provides organic nanoparticles that include a molecule having a Log P value of about 3 or above, an amphiphilic diblock copolymer or a...
US-1,007,6495 Structures for transdermal drug delivery
A preparation for the transdermal delivery of a biologically active substance into the body of a patient comprises particles of a formulation comprising the...
US-1,007,6494 Stable orally disintegrating pharmaceutical compositions
Described herein are stable orally disintegrating tablets containing a proton pump inhibitor, methods for making the same, and methods for treating subjects in...
US-1,007,6493 Medical devices including medicaments and methods of making and using same
The present invention recognizes that medical devices, such as but not limited to contact lenses, can be made having a coating made at least in part using...
US-1,007,6492 Biodegradable intravitreal tyrosine kinase implants
Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine...
US-1,007,6491 Vaccine composition
The invention provides a vaccine composition containing an antigen for inducing cellular immunity, comprising at least one first cellular immunity induction...
US-1,007,6490 Aerosol antiperspirant compositions, products and methods
An aerosol antiperspirant composition is provided. The aerosol antiperspirant composition includes a propellant having a concentration from 30% to 65% by weight...
US-1,007,6489 Aerosol antiperspirant compositions, products and methods
An aerosol antiperspirant composition is provided. The aerosol antiperspirant composition includes a propellant and an antiperspirant composition. The...
US-1,007,6488 Long-lasting powder essence composition with improved coloring and skin feeling and preparation method thereof
The present invention relates to a long-lasting powder essence composition with improved coloring and skin feeling and its preparation method. The powder...
US-1,007,6487 Comfortable, long-wearing, transfer-resistant colored cosmetic compositions
The present invention is directed to an anhydrous composition which is long wearing and transfer resistant, while at the same time providing superior comfort,...
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