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Patent # Description
US-1,011,1915 Method to treat fatty liver disease using Parabacteroides goldsteinii
The present invention describes a method to reduce blood aspartate transaminase level, liver weight, hepatic lipid accumulation and hepatocyte hypertrophy by...
US-1,011,1914 Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
Some embodiments include bacterial species for use in treatment of one or more autism spectrum disorder (ASD), and/or schizophrenia symptoms in a subject in...
US-1,011,1913 Method of reducing the likelihood of skin cancer in an individual human being
Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations...
US-1,011,1912 Herbal formulations
The present invention relates to a formulation comprising Propolis, Ginseng root and Zingiber officinale extracts to be used in the treatment, prevention of...
US-1,011,1911 Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for...
Compositions include one or more unsaturated fatty acids and one or more nitric oxide releasing compounds. Methods for using such compositions can enhance...
US-1,011,1910 Methods for treating cardiac conditions
Described herein are compositions and methods of treating a cardiac condition using modified placental tissue or an extract of a placental tissue, capable of...
US-1,011,1909 Therapeutics using adipose cells and cell secretions
The invention relates to compositions comprising (i) adipose tissue-derived cell secretions or (ii) an adipose tissue-derived cell suspension, optionally...
US-1,011,1908 Spinal disc regenerative composition and method of manufacture and use
The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of...
US-1,011,1907 Methods of treating ischemia
The invention provides compositions comprising stem and/or progenitor cells that have been treated to enhance the therapeutic properties of the cells for...
US-1,011,1906 Serum fraction of platelet-rich fibrin
The invention provides for a method of preparing an isolated serum fraction of platelet rich fibrin (PRF), comprising the steps of a. providing platelet rich...
US-1,011,1905 Antibacterial pharmaceutical preparation
The present invention refers to a pharmaceutical preparation for use as an antibacterial agent, where the pharmaceutical preparation is prepared by a method...
US-1,011,1903 Delivery vehicle for therapeutic gases
The present invention relates to a buccal delivery dosage form and its use for administration of a therapeutic gas for buccal mucosal absorption of the...
US-1,011,1902 Polymers for reversing heparin-based anticoagulation
Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding...
US-1,011,1901 Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment
The present invention relates to the combination of soluble .beta.-glucan and anti-cancer agents that affect the tumor microenvironment. Soluble .beta.-glucan...
US-1,011,1900 .beta.-glucan methods and compositions that affect the tumor microenvironment
This disclosure relates to the combination of soluble .beta.-glucan and immune suppression-relieving agents that affect the tumor microenvironment. Soluble...
US-1,011,1899 Intrapulmonary administration of polynucleotide toll-like receptor 9 agonists for treating cancer of the lung
The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of...
US-1,011,1898 Anti-tumor compositions and methods
Disclosed herein are oligonucleotide sequences that generate innate immunity in cells within tumors upon its delivery into tumors. In certain embodiments, these...
US-1,011,1897 Compositions and methods for treating cancer with JAK2 activity
Methods and compositions for diagnosing and treating JAK2 inhibitor resistant cancers are disclosed. In the disclosed methods, AKT and/or PI3K inhibitors,...
US-1,011,1896 Composition comprising a combination of DNA methylation inhibitor and a vitamin D receptor agonist for the...
The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in...
US-1,011,1895 Androgen effectors
The invention discloses novel endocrine treatment phytochemicals which affect androgenic status. The method for treatment of 5-alpha-reductase responsive...
US-1,011,1894 Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-1,011,1893 Calmangafodipir, a new chemical entity, and other mixed metal complexes, methods of preparation, compositions,...
Methods for treatment of a pathological condition caused by oxidative stress in a patient comprise administering to the patient a mixed metal complex of a...
US-1,011,1892 Anti-cancer agent
The anti-cancer agent of the present invention contains at least one kind of phosphine transition metal complex selected from a group of compounds represented...
US-1,011,1891 Compositions for oral administration of zoledronic acid or related compounds for treating disease
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions.
US-1,011,1890 9-aminomethyl minocycline compounds and uses thereof
Methods and compositions for using a tetracycline compound to treat bacterial infections are described. In one embodiment, for example, the invention provides a...
US-1,011,1889 Uses of ganaxolone
Absence epilepsy, a form of epilepsy characterized by nonconvulsive seizures, has proven to be refractive to conventional epilepsy therapies. It has been found...
US-1,011,1888 Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive...
The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the...
US-1,011,1887 Multiphasic contraceptive regimen for oral combination drug formulation of progestin and estrogen
A method for contraception includes administering to a female daily, during a time period of 21 successive days, an oral combination drug formulation of...
US-1,011,1886 Polymer conjugate for delivery of a bioactive agent
The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent...
US-1,011,1885 Compositions and therapeutic methods for the treatment of complement-associated diseases
The invention comprises methods of modulating the complement cascade in a mammal and for treating and/or preventing diseases and disorders associated with the...
US-1,011,1884 Methods and compositions for treating viral infections
The present invention provides compositions and methods for treating, preventing, and inhibiting viral replication, viral infections and viral diseases and...
US-1,011,1883 Selective P2X3 modulators
Provided herein are methods for the treatment of avoiding loss of taste response while treating a chronic cough patient with a selective P2X3 modulator.
US-1,011,1882 SYK inhibitors
The application provides methods of treating or reducing thrombocytopenia, leukopenia, anemia, or neutropenia in a patient in need thereof, comprising the step...
US-1,011,1881 Inhibitors of macropinocytosis in prevention and treatment of disease
Described herein are pharmaceutical compositions capable of inhibiting vesicle formation and methods of treatment or prophylactic administration of these...
US-1,011,1880 Compounds for the treatment of diabetes and disease complications arising from same
The present invention is directed to use of a series of tri-aryl compounds and compositions comprising the same for the treatment of diabetes and disease...
US-1,011,1879 Adrenoceptors antagonists for the prevention and treatment of neurodegenerative conditions
The present disclosure teaches methods for treating and preventing a variety of neurodegenerative conditions and symptoms associated therewith, including...
US-1,011,1878 N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as IDH2 mutants inhibitors for the treatment...
Provided are compounds of formula (I), Wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl....
US-1,011,1877 Modulators of androgen synthesis
The present specification discloses compositions comprising at least one therapeutic compound capable of modulating androgen production and methods and uses for...
US-1,011,1876 ALK Kinase Inhibitor and its use
A compound for treating a disease, in particular cancer like non-small cell lung cancer, exceptionally inhibits activity of oncogenic ALK kinase. Compositions,...
US-1,011,1875 Pyrrolopyrimidine compounds and uses thereof
The present disclosure provides pyrrolopyrimidine compounds and methods of use therefor. For example, the disclosure provides certain pyrrolopyrimidine...
US-1,011,1874 Combination therapies for treatment of cancer
Combination therapies for treatment of cancers associated with mutations in the KRAS gene are provided. Compositions comprising therapeutic agents for treatment...
US-1,011,1873 Dihydropyrimidinone derivatives
A dihydropyrimidinone derivative having a chemical structure according to Formula 1: ##STR00001## wherein Z is selected from N and O; X is selected from O...
US-1,011,1872 Fused bicyclic 2,4-diaminopyrimidine derivative as a dual ALK and FAK inhibitor
The present invention provides a compound of formula (I) ##STR00001## or a salt form thereof. The compound of formula (I) has ALK and FAK inhibitory activity,...
US-1,011,1871 Nanoparticle drug delivery system and method of treating cancer and neurotrauma
The invention provides pharmaceutical formulations of inhibitors for poly (ADP-ribose) polymerase (PARP) enzyme. The formulations can be used in the treatment...
US-1,011,1870 Method for inducing a sustained immune response
A method for inducing a sustained immune response in humans or animal patient suffering from human immunodeficiency virus (HIV) acquired immune deficiency...
US-1,011,1869 Reduction of opioid blood fluctuations
The present invention relates to the use of a sustained release matrix containing at least one opioid for producing a solid oral formulation in table form...
US-1,011,1868 Antineoplastic combinations containing HKI-272 and vinorelbine
A combination of HKI-272 compound and a vinorelbine compound in the treatment of a neoplasm is provided. Regimens, kits, and method for treatment of neoplasm,...
US-1,011,1867 Process and intermediates for the preparation of perampanel
The present invention describes a process for the synthesis of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-di-hydro-pyridin-2-one (Perampanel) represented by...
US-1,011,1866 Compounds as rearranged during transfection (RET) inhibitors
This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing...
US-1,011,1865 Methods of sedation during critical care treatment
Methods of sedating a patient undergoing critical care treatment using intravenous gaboxadol are provided.
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