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Patent # Description
US-1,022,7591 Modulation of human cytomegalovirus replication by micro-RNA 132 (miR132), micro-RNA 145 (miR145) and micro-RNA...
The present invention relates to miR145, miR132, miR212, and the genes or gene products regulated by these miRNAs. miR145 is downregulated in cells infected...
US-1,022,7590 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 214.
US-1,022,7589 Method for inhibiting tumor growth through RNA-interference using liposomally associated CDC20 siRNA
Liposomal compositions comprising of liposomes of guanidinylated cationic amphiphiles as the main lipid and cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine...
US-1,022,7588 3'end caps for RNAi agents for use in RNA interference
The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to...
US-1,022,7587 Method for constructing a plasma DNA sequencing library
The disclosure relates to a method for constructing a plasma Deoxyribonucleic acid (DNA) sequencing library. The method includes: extracting a plasma DNA;...
US-1,022,7586 Genome-originated artificial ncRNA expression library and method of preparing the same
The present invention relates to an artificial ncRNA expression library and a method for preparing the same, and particularly the present invention relates to a...
US-1,022,7585 Sequence tag directed subassembly of short sequencing reads into long sequencing reads
The invention provides methods for preparing DNA sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome...
US-1,022,7584 Methods of sequencing nucleic acids in mixtures and compositions related thereto
This disclosure relates to analyzing the end-to-end sequence and the relative distributions in heterogeneous mixtures of polynucleotides and methods and...
US-1,022,7583 Methods and systems for screening using microcapillary arrays
High-throughput methods for screening large populations of variant proteins are provided. The methods utilize large-scale arrays of microcapillaries, where each...
US-1,022,7582 Systems and methods for isolating nucleic acids from cellular samples
The present disclosure relates to systems and methods for nucleic acid isolation from cellular samples. In particular, the present disclosure provides systems...
US-1,022,7581 Engineered transcription activator-like effector (TALE) domains and uses thereof
Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One...
US-1,022,7580 Method and device for plankton separation
Methods, devices and kits for the physical separation of plankton into its component parts utilizing phototactic behavior are described. The methods utilize...
US-1,022,7579 GH61 polypeptide variants and polynucleotides encoding same
The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid...
US-1,022,7578 2G16 glucoamylase compositions and methods
The invention is directed to novel glucoamylases.
US-1,022,7577 Method for selection of high M6P recombinant proteins
Methods for the production, capturing and purification of recombinant human lysosomal proteins are described. Such recombinant human lysosomal proteins can have...
US-1,022,7576 Engineered cascade components and cascade complexes
The present disclosure provides engineered Class 1 Type I CRISPR-Cas (Cascade) systems that comprise multi-protein effector complexes, nucleoprotein complexes...
US-1,022,7575 Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof
An isolated chimeric recombinant protein has cutinase activity. The protein includes a cutinase catalytic domain and a polymer binding domain operably linked by...
US-1,022,7574 Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
This disclosure provides various TcBuster transposases and transposons, systems, and methods of use.
US-1,022,7573 Dominant negative mutations of Arabidopsis RWA
The present invention provides for dominant negative mutations of Arabidopsis REDUCING WALL ACETYLATION (RWA).
US-1,022,7572 Ketoreductase polypeptides for the reduction of acetophenones
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme....
US-1,022,7571 Lactobacillus plantarum bacteriophage Lac-PLP-1 and use thereof for inhibiting Lactobacillus plantarum...
The present invention relates to a Siphoviridae bacteriophage Lac-PLP-1 that is isolated from the nature and can kill Lactobacillus plantarum cells...
US-1,022,7570 Lactobacillus brevis bacteriophage Lac-BRP-1 and use thereof for inhibiting Lactobacillus brevis proliferation
The present invention relates to a Siphoviridae bacteriophage Lac-BRP-1 that is isolated from the nature and can kill Lactobacillus brevis cells specifically,...
US-1,022,7569 Respiratory syncytial virus expression vectors
In certain embodiments, the disclosure relates to vectors containing bacterial nucleic acid sequences and a paramyxovirus gene. Typically, the expression vector...
US-1,022,7568 Fiber scaffolds for use in esophageal prostheses
The development and construction of implantable artificial organs, and a process for manufacturing three-dimensional polymer microscale and nanoscale structures...
US-1,022,7567 Isolation and use of solid tumor stem cells
A small percentage of cells within an established solid tumor have the properties of stem cells. These solid tumor stem cells give rise both to more tumor stem...
US-1,022,7566 Three dimensional matrix for cancer stem cells
Synthetic inert 3D gel culture systems are described that can be finely tuned to exhibit desired and predetermined physical, chemical, mechanical, and...
US-1,022,7565 Generating hepatocytes
Compositions and methods are described herein for inducing reprogramming of non-pluripotent cells across lineage and differentiation boundaries to generate...
US-1,022,7564 Anti CD4 antibodies to prevent in particular graft-versus-host-disease (GvHD)
The present invention relates to, among others, an in vitro method of modifying a cell graft containing immune cells comprising the steps of incubating a cell...
US-1,022,7563 Method for culture of stem cell
The present invention enables efficient suspension culture of stem cells in a serum-free medium by comprising a step for quickly forming homogenous aggregates...
US-1,022,7562 Process for sorting motile particles from lesser-motile particles and apparatus suitable therefor
Motile particles are sorted from non-motile particles in a microfluidic sorting device wherein a stream of sort fluid containing motile and non-motile particles...
US-1,022,7561 Methods and compositions for targeting progenitor cell lines
The invention provides methods, compositions and kits for the identification and enrichment of progenitor cell lines obtained from pluripotent stem cells.
US-1,022,7559 Compounded media powder formulation and method of preparation of liquid medium for cell culture
The present invention provides a compounded cell culture medium powder formulation comprising: a basal medium powder and a cell culture media supplement,...
US-1,022,7558 Zinc-enriched biomass, method for the preparation thereof and pro-biotic, cosmetic, dietary and nutraceutic...
The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting of Streptococcus...
US-1,022,7557 Method and apparatus for producing astaxanthin
A method for producing astaxanthin incorporates a method for producing astaxanthin-rich algae cells and a method for extracting astaxanthin therefrom. An...
US-1,022,7556 Cell culture devices for biomimetic and pathomimetic cell cultures
Cell culture devices and methods of their use are provided according to aspects of the present invention which include a base having a pair of spaced apart...
US-1,022,7555 Composite sensor assemblies for single use bioreactors
A composite sensor assembly for monitoring bio-processes which is suitable for use with a polymeric bioprocess vessel or with downstream equipment, and...
US-1,022,7554 Devices, methods and systems for collecting waste from a bioreactor
The invention relates to devices, methods and systems for collecting and solidifying waste material from bioreactor cell cultures in order to facilitate waste...
US-1,022,7553 Dishwashing cleaning composition
A dishwashing composition including a copolymer which includes polyalkylene oxide groups and quaternary nitrogen atoms.
US-1,022,7552 Agent for treating textiles, containing at least one anionic, aromatic polyester and at least one non-ionic,...
An agent is provided which is to be used in the treatment of textiles, containing: i) at least one anionic, aromatic polyester, containing at least one...
US-1,022,7551 Sulfur-containing compounds as solvents
Methods for using sulfur-containing compounds comprising short chain aliphatic ester or amide moieties as solvents and compositions comprising these compounds...
US-1,022,7550 Cleaning composition
A cleaning composition comprising a surfactant combination which comprises an amine oxide amphoteric surfactant; a first anionic surfactant comprising a...
US-1,022,7549 APE-free laundry emulsifier
A detergent emulsifier for laundry and other hard surface cleaning using an APE-free surfactant blend is disclosed. The emulsifier system is efficacious for...
US-1,022,7548 Composition comprising a quat, cationic polysaccharide, and a mixture of nonionic polysaccharides
Provided is a composition, notably a fabric conditioning composition, comprising (a) a quaternary ammonium compound; (b) a cationic polysaccharide; (c) a first...
US-1,022,7547 Astragalus membranaceus seed raw oil, refined oil, preparation method therefor and use thereof
The invention belongs to the field of traditional Chinese medicine (TCM), and in particular relates to an astragalus membranaceus seed raw oil and refined oil...
US-1,022,7546 Multifunctional molybdenum containing compounds, method of making and using, and lubricating oil compositions...
Disclosed is a lubricating oil composition comprising the reaction product of a nitrogen containing reactant wherein the nitrogen containing reactant comprises...
US-1,022,7545 Additives for oilfield and industrial applications
The present invention relates to new ether carboxylic acids as high temperature stable rheology modifier, viscosifier, lubricant or emulsifier additives in...
US-1,022,7544 Automotive transmission fluid compositions for improved energy efficiency
Automotive transmission fluid compositions are provided having improved power transmission properties through the presence therein of certain defined additives,...
US-1,022,7543 Lubricant compositions
A lubricant composition includes a lubricant base oil (A) having a kinematic viscosity at 100.degree. C. of 1 to 10 mm.sup.2/s, and an ethylene/.alpha.-olefin...
US-1,022,7542 Oil compositions with improved fuel economy and durability
Disclosed is an oil composition with improved fuel economy and durability. The oil composition may be effective in improving fuel economy by reduction of...
US-1,022,7541 Lubricating oil composition for transmissions
A lubricating oil composition for transmissions is provided which improves fuel saving properties and has excellent metal fatigue life and heat resistance. The...
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