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Patent # Description
US-1,023,2000 Stem cells derived from basal portion of chorionic trophoblast layer and cell therapy comprising same
The present disclosure relates to stem cells derived from the basal portion of the chorionic trophoblast layer (bCT), which is a part of the issues of the...
US-1,023,1999 Process for preparing cholinergic neurons
The present invention relates to a method for producing cholinergic neurons comprising obtaining neural progenitor cells from stem cells so as to continuously...
US-1,023,1998 Method for chemoselection
A method of radiation-free hematopoietic stem cell (HSC) transplantation comprises administering to a mammalian subject one or two doses of 2 to 10 mg/kg body...
US-1,023,1997 Exosome-based therapeutics against neurodegenerative disorders
Methods and compositions involving exosomes or lipid nanovesicles are provided. For example, certain aspects relate to compositions comprising exosomes obtained...
US-1,023,1996 Biocampatible polymer coated silver Prussian blue nanoparticles (SPB-NPs: Ag.sub.3[Fe(CN) .sub.6])
The present invention relates to highly biocompatible or nontoxic PVP (poly(n-vinyl-2-pyrrolidone) coated silver prussian blue nanoparticles (SPB-NPS:...
US-1,023,1995 Selenium-containing compositions and uses thereof
The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent...
US-1,023,1994 Selenium-containing compositions and uses thereof
The use of selenite- or selenate-containing preparations supplemented with pharmaceutically acceptable or food-compatible acids for the preparation of an agent...
US-1,023,1993 Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders
A biocompatible polymer to which a plurality of clot-modulating peptides (CMPs) are bound. The polymer comprises repeating units of hydrophilic monomers and...
US-1,023,1992 Antioxidant composition
The present invention relates to an antioxidant composition comprising a combination of galatomannan and N-acetyl cysteine for its use in the treatment of a...
US-1,023,1991 Biomaterials comprising hyaluronic acid binding peptides and extracellular matrix binding peptides for...
The present invention provides novel biomaterial compositions and methods having a technology to improve retention of hyaluronic acid (HA). The biomaterial...
US-1,023,1990 Preservative-free composition for topical use including hyaluronic acid
The present invention relates to a sterile and/or decontaminated composition for topical use, including hyaluronic acid at a concentration of greater than or...
US-1,023,1989 Renal insufficiency progression inhibitor, prophylactic agent for renal insufficiency and indoxyl sulfate...
Provided are a novel renal failure progression inhibitor, prophylactic agent for renal failure, and indoxyl sulfate production inhibitor, intended for human...
US-1,023,1988 Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof
The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene, and...
US-1,023,1987 Maintenance of platelet inhibition during antiplatelet therapy
A method for reducing or maintaining platelet inhibition in a patient by administering cangrelor prior to an invasive procedure is described. The method of this...
US-1,023,1986 Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of HCV
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments,...
US-1,023,1985 Compounds and compositions comprising such compounds for the prevention or treatment of dyslipidaemias
The present invention relates to the field of medicine. It more particularly relates to the use of compounds for preventing and/or treating dyslipidemia in a...
US-1,023,1984 Oligomer-foscarnet conjugates
The invention relates to (among other things) oligomer-foscarnet conjugates and related compounds. A conjugate of the invention, when administered by any of a...
US-1,023,1983 Use of ACTH in assessment and prophylactic treatment of hypokalemia associated with glucocorticoid receptor...
This invention provides new methods for a) identifying Cushing's Syndrome patients at high risk of developing hypokalemia during glucocorticoid receptor...
US-1,023,1982 System and method for diagnosis and treatment
This invention relates the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the treating or preventing treatment resistant prostate...
US-1,023,1981 Subcutaneously administered anti-IL-6 receptor antibody for treatment of juvenile idiopathic arthritis
The present application discloses methods for treating an IL-6-mediated disorder such as rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA),...
US-1,023,1980 Cortexolone 17alpha-benzoate for use in the treatment of tumours
The present invention provides certain cortexolone derivatives of formula (I), and the same for use as antitumor active ingredients for the curative or...
US-1,023,1978 Anordrin compositions and methods for treating diseases
The present invention provides methods and compositions for treating cancer, reducing side effects, and reducing postmenopausal symptoms comprising anordrin or...
US-1,023,1977 Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol
Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel and ethinyl estradiol, comprising an acrylic polymer...
US-1,023,1976 Methods for the use of progestogen as a glucocorticoid sensitizer
Provided are methods and kits for administering progestogen as a glucocorticoid sensitizer to restore corticosteroid sensitivity or reverse the glucocorticoid...
US-1,023,1975 Use of aerosolized levofloxacin for treating cystic fibrosis
Methods for treating cystic fibrosis. The method includes administering to a human in need thereof an aerosol solution comprising levofloxacin or ofloxacin and...
US-1,023,1974 Pharmaceutical composition effective in preventing the adverse effects associated with the prolonged use of...
The present invention relates to pharmaceutical compositions containing a combination of reduced forms of folate, liver protectors, vitamins, and essential or...
US-1,023,1973 Salts of quinazoline derivative and method for preparing the same
The present application relates to maleates of a compound of Formula I, methods for preparing the same, pharmaceutical compositions thereof and uses thereof in...
US-1,023,1972 Combination of a 6-oxo-1,6-dihydro-pyridazine derivative having anti-cancer activity with a quinazoline derivative
A pharmaceutical composition of 3-(1-{3-[5-(1-Methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo- -1,6-dihydro-pyridazin-3-yl)-benzonitrile or a...
US-1,023,1971 Pharmaceutical composition for preventing and treating dry eye diseases, containing imatinib as active ingredient
The present invention relates to a composition for preventing or treating dry eye syndrome or eye diseases caused by dry dyes, containing imatinib as an active...
US-1,023,1970 Methods of producing heteropolycycles via bis-epoxidation
A method of synthesizing a heteropolycycle, the method involving: reacting a bisepoxide with a first heteroatom nucleophile, to obtain a mixture comprising a...
US-1,023,1969 Anti-neoplastic combinations and dosing regimens using CDK4/6 inhibitor compounds to treat RB-positive tumors
This invention directed to methods for treating select RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders using CDK4/6...
US-1,023,1968 Medicinal solution to be continuously or pulse-delivered to the eye for treating ophthalmological...
The present invention relates generally to a medicinal solution, and more particularly to a medicinal solution which is to be continuously or pulse-delivered...
US-1,023,1967 Compounds and their use as BACE inhibitors
The present invention relates to compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic...
US-1,023,1966 Combination therapy for treating pulmonary hypertension
The present disclosure describes a method of treating pulmonary disorders, such as pulmonary arterial hypertension, using a combination of a PDGF receptor...
US-1,023,1965 Molecules for administration to ROS1 mutant cancer cells
Substituted indazole derivatives of formula (I) or formula 2.(I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for...
US-1,023,1964 Compositions and methods for weight loss in at risk patient populations
The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese subject...
US-1,023,1963 Methods for treating depressive symptoms
The present application relates methods for treating a depressive symptom comprising administering an effective amount of a .mu. opioid receptor agonist or a...
US-1,023,1962 Compositions and methods for reducing major adverse cardiovascular events
The present application relates to compositions, kits, uses, systems and methods of using naltrexone and bupropion, or pharmaceutically acceptable salts...
US-1,023,1961 Pharmaceutical compositions and methods of using the same
Novel pharmaceutical compositions including cocaine hydrochloride and methods of treating patients using those pharmaceutical compositions are described.
US-1,023,1960 Methylphenidate-prodrugs, processes of making and using the same
The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or...
US-1,023,1959 Increasing expression level of apoptosis-related genes by treating a human subject with a nitroxide
Disclosed herein are methods for counteracting age-related decrease in gene expression or treating age-related diseases, for example cancers and autoimmune...
US-1,023,1958 Methods and compositions for enhancing chemotherapy
Embodiments of the invention are directed to methods and compositions using low dose sorafenib to enhance a cancer therapy.
US-1,023,1957 Histone demethylase inhibitors
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyrrolopyridine...
US-1,023,1956 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof
4-Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a...
US-1,023,1955 Enhanced delivery of immunosuppressive drug compositions for pulmonary delivery
The present invention includes compositions and methods for making and using a rapid dissolving, high potency, substantially amorphous nanostructured aggregate...
US-1,023,1954 Neurodegenerative therapies
The present invention provides a compound of formula (I) wherein: Y represents a C or N atom which may be substituted or form a cyclic group with R''' but may...
US-1,023,1953 Inhibitors of bromodomains
The present disclosure relates to compounds capable of acting as covalent inhibitors of bromodomains and the therapeutic use of these inhibitors.
US-1,023,1952 Use of arginine vasopressin receptor antagonists for the treatment of prostate cancer
Described herein are methods of decreasing the proliferation of prostate cancer cells in a mammalian subject by administering to a subject in need thereof a...
US-1,023,1951 Tesofensine, beta blocker combination formulation
The present invention relates to a controlled release formulation comprising the active compounds tesofensine and a beta blocker, such as metoprolol or...
US-1,023,1950 Erythromelalgia treatment
The present invention is directed to the treatment of erythromelalgia comprising administering to a subject in need thereof, a therapeutically effective amount...
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