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Patent # Description
US-1,023,3473 Cellulolytic enzyme compositions and uses thereof
The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the...
US-1,023,3472 Preparation of malto-oligosaccharides
Disclosed is a method for preparing a mixture of malto-oligosaccharides. Generally, a dry-milled corn fraction, such as a corn flour from which germ and fiber...
US-1,023,3471 Methods of preconditioning pretreated cellulosic material
The invention relates to methods of preconditioning pretreated cellulosic material in the presence of a combination of phenol oxidizing enzyme and glucoamylase....
US-1,023,3470 Secretion of fatty acids by photosynthetic microorganisms
Recombinant photosynthetic microorganisms that convert inorganic carbon to secreted fatty acids are described. Methods to recover the secreted fatty acids from...
US-1,023,3469 Method for extracting molecules produced by anaerobic fermentation from fermentable biomass
Process for extracting volatile fatty acids (VFA), organic molecules called precursors produced by microorganisms (M) in a fermentation reactor (2) by anaerobic...
US-1,023,3468 High molecular weight PHA-producing microbe and method of producing high molecular weight PHA using same
An object of the present invention is to provide a microorganism strain that accumulates a high molecular weight PHA, and a PHA production method using the...
US-1,023,3467 Two-stage production of higher alcohols
Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate...
US-1,023,3466 Economic ethanol fermentation sugar stream, processes and systems of producing same
Methods and system for producing a slip stream of sugar, for example for use in the production of one or more chemicals, in ethanol fermentation facilities. In...
US-1,023,3465 Optimal soybean loci
As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion...
US-1,023,3464 HIV pre-immunization and immunotherapy
The present invention relates generally to immunization and immunotherapy for the treatment or prevention of HIV. In particular, the methods include in vivo...
US-1,023,3463 Neurotensin-induced tumor formation is regulated by micro RNA 133A-aftiphilin-dependent receptor recycling
This application discloses methods of treating, preventing, and diagnosing colorectal cancer and IBD in a subject comprising administering an effective dose of...
US-1,023,3462 Methods and compositions for root knot nematode control
The present invention discloses gene targets, constructs and methods for the genetic control of plant disease caused by nematodes of the genus Meloidogyne (root...
US-1,023,3461 Nucleotide sequences and corresponding polypeptides conferring modulated growth rate and biomass in plants...
The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size,...
US-1,023,3460 Nucleotide sequences and corresponding polypeptides conferring modulated growth rate and biomass in plants...
The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of improved plant size,...
US-1,023,3459 Plants having altered agronomic characteristics under nitrogen limiting conditions and related constructs and...
Isolated polynucleotides and polypeptides, and recombinant DNA constructs useful for conferring improved nitrogen use efficiency and/or drought stress...
US-1,023,3458 Carbon fixation systems in plants and algae
Provided are methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and...
US-1,023,3457 Inhibition of a xylosyltransferase to improve saccharification efficiency
The invention provides compositions and methods for inhibiting the expression of the gene XAX1 in grass plants. Plants with inhibited expression of XAX1 have...
US-1,023,3456 Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
Methods of gene stacking are described herein. The methods can be used to repeatedly add genes into a chosen locus in a precise manner, which ensures...
US-1,023,3455 Plant transformation without selection
The invention provides methods for identifying regenerated transformed plants and differentiated transformed plant parts, obtained without subjecting plant...
US-1,023,3454 DNA vectors, transposons and transposases for eukaryotic genome modification
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel transposons and...
US-1,023,3453 Generating targeted sequence diversity in fusion proteins
Methods of generating fusion protein variants are provided that comprise introducing sequence diversity at the junction region or regions in the fusion and...
US-1,023,3452 Compositions and methods for increasing erythropoietin (EPO) production
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting one or more EGLN genes, EGLN1, EGLN2 and/or EGLN3 and methods of using...
US-1,023,3451 Method of regulating gene expression
The present invention relates, in general, to gene expression and, in particular, to a method of inhibiting the expression of a target gene and to constructs...
US-1,023,3450 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as...
US-1,023,3449 Methods and compositions for selecting siRNA of improved functionality
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize...
US-1,023,3448 Modified double-stranded RNA agents
One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The sense strand of the...
US-1,023,3447 Self-cleaving ribozymes and uses thereof
In certain embodiments, the disclosure relates to compositions and methods relating to a ribozyme-based gene regulation system that functions in mammalian...
US-1,023,3446 Micro-RNA inhibitor
The invention provides a microRNA inhibitor that has two or more sequences complementary to the sequence of microRNA to be the target of inhibition, which two...
US-1,023,3445 Composition for delivery of genetic material
The present invention relates to exosomes, loaded with genetic material and methods of producing them and to the use of such exosomes for delivering genetic...
US-1,023,3444 Crude biological derivatives competent for nucleic acid detection
The invention relates to methods for the detection of a specific sequence of RNA in a cell or tissue sample. The invention also relates to methods to...
US-1,023,3443 Reducing adapter dimer formation
Provided herein is a method of reducing adapter dimer formation comprising contacting a sample comprising target nucleic acid sequences with 5' and 3' adapters...
US-1,023,3442 Method for affinity purification
The disclosure relates to a switchable aptamer having a high affinity for a selected target such as a virus, cell or antibody when in the presence of a binding...
US-1,023,3441 Capillary barriers for staged loading of microfluidic devices
Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic...
US-1,023,3440 Methods for DNA and RNA extraction from fixed paraffin-embedded tissue samples
Methods and reagents are provided for the rapid extraction of nucleic acids from a fixed paraffin embedded sample (e.g., a FFPET sample). In some embodiments,...
US-1,023,3439 Directed modification of glucosamine synthase mutant and application thereof
The present invention discloses a directionally modified glucosamine synthase mutant and its application. The amino acid sequence of the glucosamine synthase...
US-1,023,3438 Engineered primate L-methioninase for therapeutic purposes
Methods and compositions relating to the engineering of an improved protein with methionine-.gamma.-lyase enzyme activity are described. For example, in certain...
US-1,023,3437 Hypochlorite resistant cyanuric acid hydrolases and methods of use thereof
The present invention relates to engineered cyanuric acid hydrolase enzymes that are resistant to hypochlorite and compositions and devices comprising such...
US-1,023,3436 ADAMTS13-containing compositions having thrombolytic activity
This invention relates to a pharmaceutical composition having thrombolytic activity comprising ADAMTS13, and to methods for treating or preventing a disorder...
US-1,023,3435 Glycoside hydrolases from thermophlic fungi
The present invention relates to isolated polypeptides having cellulolytic activity or hemicellulolytic activity and polynucleotides encoding the polypeptides....
US-1,023,3434 Process for treating an arabinoxylan-containing substrate
The present invention relates to isolated polypeptides having alpha-L-arabinofuranosidase activity and isolated nucleic acid sequences encoding the...
US-1,023,3433 Bifidobacterium longum
A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
US-1,023,3432 Materials and methods for characterizing and using a 3-ketoacyl-acyl carrier protein (ACP) synthase III...
A mutant Bacillus subtilis, which does not express a functional KASIIIA and/or KASIIIB, and method of making; a mutant Rhodospirillum rubrum, which does not...
US-1,023,3431 Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
The present invention provides for a polyketide synthase (PKS) capable of synthesizing a 3-hydroxycarboxylic acid or ketone. The present invention also provides...
US-1,023,3430 Glucose oxidase having improved thermostability
A glucose oxidase having improved thermostability is disclosed. The amino acid sequence of the glucose oxidase is a modified amino acid sequence of SEQ ID NO:...
US-1,023,3429 Hand, foot, and mouth vaccines and methods of manufacture and use thereof
The present disclosure relates to hand, foot, and mouth disease vaccines and immunogenic compositions having one or more antigens from at least one virus that...
US-1,023,3428 Restrictive inverted terminal repeats for viral vectors
This invention relates to modified parvovirus inverted terminal repeats (ITRs) that do not functionally interact with wild-type large Rep proteins, synthetic...
US-1,023,3427 Fiber scaffolds for use in esophageal prostheses
The development and construction of implantable artificial organs, and a process for manufacturing three-dimensional polymer microscale and nanoscale structures...
US-1,023,3426 Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds
The present invention provides a method for inducing cardiac differentiation of a pluripotent stem cell, which comprises the steps of (1) culturing a...
US-1,023,3425 CD137 enrichment for efficient tumor infiltrating lymphocyte selection
The invention includes compositions and methods to rapidly isolate and culture cells that are potent for use in adoptive immunotherapy. In one embodiment, the...
US-1,023,3424 Compositions and methods including cytotoxic B lymphocyte cell line expressing exogenous membrane...
Compositions and methods are disclosed herein for producing one or more immunoglobulins in an isolated cytotoxic B lymphocyte cell line. An isolated cell line...
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