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Patent # Description
US-1,023,3271 Process for producing propylene polymer compositions
The present invention relates to a process for producing polypropylene polymer composition by polymerizing propylene with a C4 to C8 a-olefin comonomer and with...
US-1,023,3270 Fluorinated catalyst supports and catalyst systems
Catalyst systems and methods for making and using the same. A method for making a catalyst support includes forming a mixture of a support material and a...
US-1,023,3269 Compound containing structural unit derived from vinyl ether compound
A compound containing a structural unit derived from a novel vinyl ether compound. This compound contains a structural unit represented by formula (1), in which...
US-1,023,3268 Modified catalyst supports
The invention covers a supported catalyst system prepared according to a process comprising the following step: i). impregnating a silica-containing catalyst...
US-1,023,3267 Method for preparing acrylonitrile-butadiene-styrene graft copolymer and acrylonitrile-butadiene-styrene...
The present invention relates to a method for preparing an acrylonitrile-butadiene-styrene graft copolymer having improved impact strength, which comprises: a...
US-1,023,3266 Method to prepare rubber compounds containing silicon dioxide for the production of tyres
A rubber compound containing silicon dioxide for the production of tires and comprising a polymer base with a cross-linkable unsaturated chain, a filler...
US-1,023,3265 Modified conjugated diene polymer and method for preparing the same
Disclosed are a modified conjugated diene polymer and a method for preparing the same. The modified conjugated diene polymer and the method for preparing the...
US-1,023,3264 Process for preparing (1.fwdarw.6)-.alpha.-D-glucan
A process for preparing (1.fwdarw.6)-.alpha.-D-glucan. A large amount of (1.fwdarw.6)-.alpha.-D-glucan can be prepared from banana by using this process. The...
US-1,023,3263 Method for preparation of sugammadex sodium
The present invention provides a method for improved preparation of Sugammadex sodium.
US-1,023,3262 Glycan analysis
The present invention concerns methods of derivatizing sialic acids which may be present on glycan moieties. This can be of use in determining the glycosylation...
US-1,023,3261 Natural polymer nanoparticles from ionic liquid emulsions
A method of making natural polymer (nano)particles, comprises two immiscible phases and a surface active agent, wherein one phase includes a natural polymer...
US-1,023,3260 Process for the functionalization of a surface
A functionalization is performed with a dissolved oligo- or polysaccharide derivative which contains at least one free functional group, especially an amino...
US-1,023,3259 Hypromellose acetate succinate, method for producing the same and composition containing the same
Provided are hypromellose acetate succinate (HPMCAS) which exhibits high solubility and can suppress generation of undissolved materials when dissolved in a...
US-1,023,3258 Bispecific binding proteins that bind CD40 and mesothelin
The present disclosure provides bispecific proteins that bind to two antigens, as well as their compositions, uses, and methods of making.
US-1,023,3257 Methods for preparing antibody-drug conjugates
This invention describes a method of conjugating a cell binding agent such as an antibody with an effector group (e.g., a cytotoxic agent) or a reporter group...
US-1,023,3256 Antibodies directed to ricin toxin
An isolated monoclonal antibody or any antigen-binding fragment thereof which binds to ricin toxin, an expression vector including the isolated nucleic acid...
US-1,023,3255 Antibody therapeutics that bind STAT3
The present disclosure provides anti-STAT3 antibodies, and antigen-binding portions thereof. In certain embodiments, the antibodies or fragments thereof, are...
US-1,023,3254 Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof
Provided is a monoclonal antibody which specifically recognizes B cell lymphoma cells and a use thereof. More specifically, provided are the monoclonal...
US-1,023,3253 Antibodies for treatment of cancer expressing claudin 6
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDN6, including...
US-1,023,3252 pH-dependent antibodies targeting the transferrin receptor and methods of use thereof to deliver a therapeutic...
A pH-dependent antibody that binds an antigen with high affinity at a first pH and rapidly dissociates at a second pH, wherein the antigen is a transferrin...
US-1,023,3251 Antibody therapeutics that bind CD137
There is disclosed compositions and methods relating to or derived from anti-CD137 antibodies. More specifically, there is disclosed fully human antibodies that...
US-1,023,3250 Human antibodies to the glucagon receptor and methods of use thereof for lowering blood glucose or ketone levels
The present invention provides antibodies that bind to the human glucagon receptor, designated GCGR and methods of using same. According to certain embodiments...
US-1,023,3249 Antibodies and methods for treating estrogen receptor-associated diseases
Provided herein in certain embodiments are antibodies, antibody fragments, pharmaceutical compositions, methods for modulating the functions of estrogen...
US-1,023,3248 Treatment of C1013G/CXCR4-associated waldenstroom's macroglobulinemia with an anti-CXCR4 antibody
The present disclosure provides a method for treating a subject afflicted with Waldenstrm's macroglobulinemia (WM) comprising administering to the subject a...
US-1,023,3247 Method of modulating the activity of functional immune molecules
The invention relates to a method for controlling the activity of an immunologically functional molecule, such as an antibody, a protein, a peptide or the like,...
US-1,023,3246 Antibody and antibody fragment introduced new modification sites
The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic...
US-1,023,3245 Methods of treating inflammatory and autoimmune diseases with natalizumab
Natalizumab is a safe and efficacious treatment for inflammatory and autoimmune diseases, such as multiple sclerosis, Crohn's Disease, and rheumatoid arthritis....
US-1,023,3244 Anti-ITGA3 antibodies, activatable anti-ITGA3 antibodies, and methods of use thereof
The invention relates generally to antibodies that bind ITGa3, activatable antibodies that specifically bind to ITGa3 and methods of making and using these...
US-1,023,3243 Anti-FcRn antibodies
The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally...
US-1,023,3242 CTLA4 fusion proteins for the treatment of diabetes
A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus autoimmunity by administering an effective amount of a cytotoxic...
US-1,023,3241 Opioid receptor binding agents and uses thereof
Agents that specifically bind to an opioid receptor in a conformationally specific way can be used to induce a conformational change in the receptor. Such...
US-1,023,3240 Methods for treating cholestatic liver fibrosis
Provided are methods of treating fibrotic conditions in a subject by the identification of specific subsets of fibrogenic myofibroblasts, such as portal...
US-1,023,3239 Isolated host cells expressing anti-IL-6 antibodies
The present invention is directed to antibodies and fragments thereof and humanized versions thereof having binding specificity for IL-6. Another embodiment of...
US-1,023,3238 TNF alpha antibody or fragment thereof and methods of use
The present invention relates to anti-TNF alpha binding members and in particular to monovalent, high potency TNF alpha-binding antibody fragments being highly...
US-1,023,3237 Heterodimeric immunoglobulins
The present application is directed to heterodimeric antibodies and methods of use.
US-1,023,3236 Method of treating or preventing rheumatoid arthritis
This invention is in the field of treating or preventing rheumatoid arthritis in humans and animals. In particular, the invention relates to methods for...
US-1,023,3235 Modulating the alternative complement pathway
Provided herein are compositions, including pharmaceutical compositions, and methods for modulating, i.e., stimulating or inhibiting, activity of the...
US-1,023,3234 Binding moieties for biofilm remediation
Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies suitable for administration to a selected...
US-1,023,3233 Lipopolysaccharide-targeted peptide mimic vaccine against Q fever
A vaccine and method of vaccination for conferring immunity to Q fever is described. The vaccine comprises a polypeptide with a sequence of SLTWHKHELHRK (SEQ ID...
US-1,023,3232 Norovirus antibodies
The present invention relates to a binding polypeptide specifically binding to the amino acid sequence W-V-N-X.sup.1-F-Y-X.sup.2 (SEQ ID NO: 1), wherein X.sup.1...
US-1,023,3231 Feeding strategies and purification processes for monoclonal antibody production
This invention provides an improved process for manufacturing a Rabies monoclonal antibody (HuMab 17C7) that results in low osmolality, minimum secondary...
US-1,023,3230 Use of a long acting GLP-1/glucagon receptor dual agonist for the treatment of non-alcoholic fatty liver disease
The present invention relates to a pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease including a long-acting...
US-1,023,3229 Engineered monomeric antibody fragments
The present invention relates to monomeric polypeptides comprising an engineered monomeric antibody fragment (e.g., monomeric Fc-containing polypeptides)...
US-1,023,3228 Albumin derivatives and variants
The application discloses albumin derivatives comprising or consisting of domain III and at least one further domain wherein the derivative or variant is not a...
US-1,023,3227 Isoform of the TGF-beta receptor II
An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGF.beta.-1...
US-1,023,3226 Methods and compositions for chimeric antigen receptor targeting cancer cells
The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and...
US-1,023,3225 Single chain insulin agonists exhibiting high activity at the insulin receptor
Single chain insulin analogs are provided having high potency and specificity for the insulin receptor. As disclosed herein optimally sized linking moieties can...
US-1,023,3224 Nucleic acids encoding a fusion protein useful for multi-level specific targeting of cancer cells
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R.alpha.2 binding ligand; at least one effector...
US-1,023,3223 Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has...
US-1,023,3222 Methods, compositions, diagnostics and assays for the treatment of Alzheimer's disease
The invention provides compounds for the treatment of Alzheimer's disease, methods for the use of such compounds, assays for the identification of such...
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