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Patent # Description
US-1,023,8783 Guidable intravascular blood pump and related methods
An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features...
US-1,023,8782 Magnetic fixation apparatus for percutaneous catheter
A catheter apparatus can include a first magnet coupled to a catheter and a second magnet configured to couple to a patient's skin. When the catheter and the...
US-1,023,8781 Blood bag system and blood treatment method
A blood bag system includes: a first bag in which blood containing multiple components is stored; a second bag in which a relative medium-density component is...
US-1,023,8780 Delivery-and-fluid-storage bridges for use with reduced-pressure systems
Systems, methods, and apparatuses are presented that facilitate the provision of reduced pressure to a tissue site by using a delivery-and-fluid-storage bridge,...
US-1,023,8779 Condensate absorbing and dissipating system
A dressing for treating a tissue site may include a base layer, a sealing member, a first and a second wicking layer, and an absorbent layer. The base layer may...
US-1,023,8778 Automatically switching different aspiration levels and/or pumps to an ocular probe
Methods and apparatuses for automatically switching different aspiration levels to an ocular probe are disclosed herein. The probe may be a phacoemulsification...
US-1,023,8777 Hydrophobic porous non mechanical valve for medical suction device
The present invention provides a porous non mechanical valve which retards or prevents the passage of bodily fluids and is resistant to being occluded or...
US-1,023,8776 Hydrophobic catheter and composition
In various embodiments, a surgical catheter is provided. The catheter may comprise one or more hydrophobic barrier layers made from an ...
US-1,023,8775 Bone repair material
Sliceable bone repair material is a porous block-shaped scaffold containing a hydrogel, wherein the hydrogel is formed by Michael type addition of at least two...
US-1,023,8774 Biological implant
Provided is a biological implant which exhibits high binding ability to a biological tissue after having been embedded in a living organism, which secures an...
US-1,023,8773 Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and...
The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices.
US-1,023,8772 Biodegradable composite scaffold for repairing defects in load-bearing bones
A tissue scaffold for repair and regeneration of bone hard tissue or muscle, skin, or organ soft tissue, including load-bearing bone tissue, the scaffold...
US-1,023,8771 Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
Methods for treating a bioprosthetic tissue are described herein. The methods comprise contacting the bioprosthetic tissue with at least one nucleophile and/or...
US-1,023,8770 Reparative cell isolation and delivery
Methods are described for generating autologous tissue grafts, including generating grafts at the point of care, which include isolated cell populations that...
US-1,023,8769 Graft for directed vascular and lymphatic regeneration and methods to guide endothelial cell assembly
Embodiments of the present invention relate to a therapeutic device (graft) comprising a collagen membrane having an aligned uniaxial or biaxial structure such...
US-1,023,8768 Wound-healing and hemostatic sponge of squid ink polysaccharide/chitosan, preparation method and use thereof
A wound-healing and hemostatic sponge of squid ink polysaccharide/chitosan, a preparation method and use thereof are provided. The sponge comprises squid ink...
US-1,023,8767 Mono-layer thin film adhesive compounds and methods of synthesis and use
The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
US-1,023,8766 Diagnostic composition for identifying amniotic fluid
The present invention relates to the field of medical diagnostics and more specifically, to identification of amniotic fluid.
US-1,023,8765 Photocatalytic honeycomb assembly and photocatalytic purification apparatus
A photocatalytic honeycomb assembly and a photocatalytic purification apparatus, which can maximally increase a contact area between polluted air and a...
US-1,023,8764 Aromatherapy vaporization device
A novel herbal vaporization device (HVD) and method is disclosed. The HVD includes a recharging unit for storing therein of a vaporization unit having a heating...
US-1,023,8763 Sterilizing floor array
Various devices for sterilizing a surface and an object in contact with the surface are disclosed. For example, a first device includes an ultraviolet light...
US-1,023,8762 Incorporating metals, metal oxides and compounds on the inner and outer surfaces of nanotubes and between the...
A multi-walled titanium-based nanotube array containing metal or non-metal dopants is formed, in which the dopants are in the form of ions, compounds, clusters...
US-1,023,8761 Method and an integrated device for an area decontamination process
The present invention is an improved method for decontamination of a space and an integrated device that completes the decontamination cycle extremely fast...
US-1,023,8760 System and method for probe cleaning and disinfecting
Embodiments of the invention are directed to apparatuses and methods for cleaning and disinfecting probes. A cleaner is utilized to remove foreign materials...
US-1,023,8759 Power supply connector for a submersible pump and light source
A method of supplying power to a storage tank, can include attaching a power supply connector to a submersible pump wherein the power supply connector is...
US-1,023,8758 Radiolabeled alpha-melanocyte stimulating hormone hybrid peptide for melanoma targeting
The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in...
US-1,023,8757 Methods and compositions for detection of cancer
A molecular probe for use in detection of cancer cells expressing an Ig superfamily cell adhesion molecule that binds in a homophilic fashion in a subject...
US-1,023,8756 Lipid nanoparticles and uses thereof
The present invention relates to lipid-associated indocyanine green particles for enhanced functional high-resolution near-infrared fluorescence medical imaging...
US-1,023,8755 Methods and compositions for regulation of cell aging, carcinogenesis and reprogramming
Compositions and methods described herein include somatic cells that are competent for reprogramming and malignant transformation and are characterized by a...
US-1,023,8754 Lipid nanoparticle compositions and methods for MRNA delivery
Disclosed herein are compositions and methods for modulating the production of a protein in a target cell. The compositions and methods disclosed herein are...
US-1,023,8753 Antisense conjugates for decreasing expression of DMPK
The disclosure provides novel conjugates comprising antisense oligonucleotides that hybridize to a DMPK transcript and a 3E10 antibody or binding fragment...
US-1,023,8752 Single-stranded nucleic acid molecule for regulating expression of gene having delivering function
The invention provides a single-stranded nucleic acid capable of inhibiting expression of a target gene having a delivery function. The nucleic acid contains,...
US-1,023,8751 Cytotoxic benzodiazepine derivatives
The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula...
US-1,023,8750 Porphyrin modified telodendrimers
The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior....
US-1,023,8749 Angiotensinogen (AGT) iRNA compositions and methods of use thereof
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the angiotensinogen (AGT) gene, and methods of using such RNAi agents...
US-1,023,8748 Anti-CDH6 antibody drug conjugates
The present invention relates to anti-CDH6 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
US-1,023,8747 Method for inducing an immune response against avian, swine, spanish, H1N1, H5N9 influenza viruses and...
A vaccine for immunization against Type A influenza virus is provided having an immunologically effective amount of peptide constructs obtained by linking...
US-1,023,8746 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
A substantially surface active agent tree composition which includes a hydrophobic solvent, and/or a petrolatm, a paraffin wax and/or a fatty alcohol, a fatty...
US-1,023,8745 Cannabinoid composition and products including .alpha.-tocopherol
A cannabinoid composition having an excipient including .alpha.-tocopherol and at least one isolated cannabinoid having a purity of greater than 80%. The...
US-1,023,8744 High load dispersions
The present invention relates to the field of carrier and delivery systems for active molecular compounds. In particular, the present invention provides aqueous...
US-1,023,8743 C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use
In its many embodiments, the present invention provides certain C5-C6 fused tricyclic iminothiadiazine compounds, including compounds Formula (I): or a tautomer...
US-1,023,8742 Cell penetrating nucleolytic antibody based cancer therapy
Cancer cells with defects in DNA repair are highly susceptible to DNA-damaging agents, but delivery of therapeutic agents into cell nuclei can be challenging. A...
US-1,023,8741 Nucleic acid constructs for presentation of CD4 and CD8 epitopes, cellular transfection and uses thereof
The invention relates to constructs, cells and methods for modulating the immune system that optimize presentation of CD4 and CD8 epitopes to antigen-presenting...
US-1,023,8739 Manufacture of surfactant-containing compositions with enhanced stability
Improved methods for the manufacture of pharmaceutical compositions comprising at least one surfactant, involving prefiltration of the surfactant prior to...
US-1,023,8738 Methods of modulating immune system responses
Novel methods and uses for modulating immune responses are provided. The methods and uses involve the use of a TIFA activator such heptose-1,7-5 bisphosphate or...
US-1,023,8737 Oral administration of at least one pharmaceutical and/or antigenic active substance
Disclosed is a gastro-resistant vector for the oral administration of at least one pharmaceutical and/or antigenic active substance including an aqueous phase...
US-1,023,8736 Adjuvant compositions
This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators;...
US-1,023,8735 Controlled activation of complement components for use as endogenous adjuvant
The invention relates to a pharmaceutical composition made of one or more preparation and comprising a therapeutically effective dose of at least one...
US-1,023,8734 Compositions and methods for self-adjuvanting vaccines against microbes and tumors
The present invention is drawn to compositions and methods to enhance an immune response in order to prevent or treat infections or hyperproliferative diseases...
US-1,023,8732 RSV F protein mutants
The present disclosure relates to RSV F protein mutants, nucleic acids or vectors encoding a RSV F protein mutant, compositions comprising a RSV F protein...
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