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Patent # Description
US-1,023,8731 Chikagunya virus RNA vaccines
The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines...
US-1,023,8730 Cold-adapted-viral-attenuation (CAVA) and novel attenuated poliovirus strains
A poliovirus (PV) strain was attenuated by a novel method of Cold-Adapted-Viral-Attenuation (CAVA). The resulting recombinant attenuated PV, CAVA-PV, shows...
US-1,023,8729 Cancer and skin lesion treatment
A method for treating or reducing the incidence of recurrence of cancer, benign tumors or HPV-associated lesions, including skin cancer, and particularly...
US-1,023,8728 Peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,8727 Peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
A method of treating a patient who has prostate cancer includes administering to said patient a composition containing a population of activated T cells that...
US-1,023,8726 Peptides and combination of peptides for use in immunotherapy against CLL and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,8725 Peptides and combination of peptides for use in immunotherapy against CLL and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,8724 Peptides and combination of peptides for use in immunotherapy against CLL and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,8723 Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
The present disclosure provides compositions comprising mature dendritic cells loaded with autologous tumor cell lysates for the treatment of liver cancers,...
US-1,023,8722 Pigment epithelium derived factor (PEDF) for the treatment of uterine fibroids
A method of treating uterine fibroid in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective...
US-1,023,8721 Therapeutic acid ceramidase compositions and methods of making and using them
The present invention relates to a therapeutic composition including a ceramidase mixture and a pharmaceutically acceptable carrier, where the ceramidase...
US-1,023,8720 Stabilized liquid and lyophilized ADAMTS13 formulations
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized...
US-1,023,8719 Compositions and kits for enzymatic debridement and methods of using the same
A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of...
US-1,023,8718 Factor VIII formulation
The invention relates to factor VIII compositions and their use.
US-1,023,8717 Parenteral glucagon formulations
This invention relates to compositions of glucagon suitable for administration by manual injection or by an insulin pump or other injection device to treat...
US-1,023,8716 Anti-P2X.sub.7 peptides and epitopes
The invention relates to the identification of a novel epitope on non-function P2X.sub.7 receptors which are implicated in cancer. The epitope includes a region...
US-1,023,8715 Methods for treating or reducing the risk of arthritis in a subject by administering gelsolin
The invention relates to the use of gelsolin to treat inflammatory diseases (e.g., rheumatoid arthritis) and to the use of gelsolin to diagnose, monitor, and...
US-1,023,8714 Method for forming an immune-tolerant site and method for attracting immunosuppressive cells
A method for forming an immune-tolerant site, and a method for attracting immunosuppressive cells, comprising contacting an agent comprising SEK-1005 (Ser, ...
US-1,023,8713 Cyclic tetrapeptides and therapeutic applications thereof
There are provided compounds of formula I: ##STR00001## wherein k, m, n, p, R, R', R'', R''', R.sup.3, R.sup.4, R.sup.7 and R.sup.8 are as defined in the...
US-1,023,8712 Compositions useful for the treatment of gastrointestinal disorders
This invention provides novel peptides and methods to prevent, control, and treat an inflammation, cancer and other disorders, particularly of the...
US-1,023,8711 Extracellular histones as biomarkers for prognosis and molecular targets for therapy
Hyper-inflammatory responses can lead to a variety of diseases including sepsis. It is now shown that extracellular histones released in response to...
US-1,023,8710 Peptide having anti-inflammatory, osteogenic and hair growth promoting activities, and use of same
Provided is a peptide, which has an anti-inflammatory activity and an activity for promoting osteogenic differentiation, formed from the amino acid sequence...
US-1,023,8709 Method of treating diseases
Methods of treating acromegaly in a subject are described herein. Exemplary methods include orally administering to the subject at least once daily at least one...
US-1,023,8708 Sebum control and anti-acne composition
Compositions that include Psidium guajava fruit extract or Kunzea ericoides leaf extract or both for reducing sebum production in sebaceous glands are disclosed.
US-1,023,8707 Composition for the prevention and/or treatment of allergy symptoms
The present invention relates to a pharmaceutical composition or a food supplement composition and use thereof in the prevention and/or treatment of allergy...
US-1,023,8706 Condensible gas botanical extraction systems and methods
An apparatus for the extraction of compounds from botanical material using a condensable gas solvent includes an extraction chamber wherein the feedstock is...
US-1,023,8705 Pharmaceutical composition and method of manufacturing
The present invention provides for methods of obtaining an extract of Cannabis plant material as well as subsequent processing of the extract to provide a...
US-1,023,8704 Pre moistened wipes for use in treating anal rectal irritations and disorders
Many people who suffer from anal rectal discomfort and disorders need fibrous sheet materials which are pre-moistened with a solution for improved cleansing...
US-1,023,8703 Nutritional supplements affecting mood state
Nutritional supplement compositions for mood enhancement are disclosed. A nutritional supplement composition can include one or more of plant material from pine...
US-1,023,8702 Pharmaceutical composition, preparation method therefor and use thereof
The pharmaceutical composition is a formulation prepared by the raw materials in parts by weight: 1-300 parts of chlorogenic acid and 1-50 parts of Ganoderma...
US-1,023,8701 Composition of wood ear, shiitake, hawthorn fruit, roselle, celery and fruit of chinese plum for treatment...
The invention provides a water extract of Yan-Sheng-Yin (YSY), a Chinese natural dietary supplement for treatment and/or prevention of hyperlipidemia,...
US-1,023,8700 Oncolytic virus adjunct therapy with agents that increase virus infectivity
Provided are adjunct therapies for use in combinations and compositions with an oncolytic virus, such as a vaccinia virus. The adjunct therapies include...
US-1,023,8699 Tropic cell based virotherapy for the treatment of cancer
In some embodiments, methods of killing tumor cells are provided. The methods may include contacting the tumor cell with a tropic cell that carries a modified...
US-1,023,8698 Biomarkers and combination therapies using oncolytic virus and immunomodulation
The invention disclosed herein describes biomarkers useful for prognosis, selection and monitoring of oncolytic virus therapy for patients with various types of...
US-1,023,8697 Lactococcus lactis producing TSLP or IL-25 and their uses as probiotics and therapeutics
The present invention relates to recombinant Lactococcus lactis bacteria expressing and secreting TSLP or IL-25 or a combination thereof, and their use as...
US-1,023,8696 Lactic acid bacteria and use thereof
Lactic acid bacteria, which are isolated Lactococcus lactis subsp. lactis LL358 and isolated Lactobacillus salivarius LS159 respectively. By administering a...
US-1,023,8695 Use of microorganisms for reducing the level of trimethylamine in a human body cavity, in particular for the...
Composition containing a microorganism, preferably an Archaea, expressing a TMA methyltransferase and a TMA methyl group acceptor corrinoid protein, capable of...
US-1,023,8694 Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and...
US-1,023,8693 Spinal disc regenerative composition and method of manufacture and use
The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of...
US-1,023,8692 Composition comprising a culture solution of mesenchymal stem cells for the treatment of neural diseases
Provided are a pharmaceutical composition for prevention and treatment of a neural disease including at least one selected from the group consisting of...
US-1,023,8691 Peptides and scaffolds for use in immunotherapy against head and neck squamous cell carcinoma and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,8690 Modified T lymphocytes comprising an inducible caspase and methods of apoptosis
Provided herein are cells, e.g., T cells expressing artificial cell death polypeptides that cause death of a cell, e.g., cells (e.g., T lymphocytes) expressing...
US-1,023,8689 Methods for combating bacterial infections by killing persister cells with mitomycin C and/or cisplatin
The present disclosure provides a method for killing persister cells with mitomycin C and/or cisplatin, or derivatives thereof. Recalcitrant infections are...
US-1,023,8688 Combination therapies for bladder cancer
The disclosure provides drug combinations and methods for treating human bladder cancer. The drug combination may include mitomycin, or an analog thereof,...
US-1,023,8687 Method for preparing a liposomal rehydration salt formulation
A liposomal rehydration salt formulation comprising phosphatidylcholine liposomes, salts, water, and a percentage inclusion ratio of salts (salts retained...
US-1,023,8686 Antimicrobial skin cream
A cream for treating the skin may include gray clay kaolin; sodium lauryl ether sulfate; blue tartrazine; sodium chloride; menthol; metabisulfite sodium;...
US-1,023,8685 Compositions containing polymeric sulfur and uses thereof
This invention relates to personal care compositions and methods of treating topical skin conditions using compositions containing polymeric sulfur S.sub.n. The...
US-1,023,8684 Micro- and nano-quantity sleep enhancing nutrient composition and method of enhancing central nervous system...
The present invention relates to a dietary supplement, composition, nutraceutical, and/or system for inducing or treating biological responses or conditions...
US-1,023,8683 Methods for promoting entry of an agent into a cell
A method for promoting entry of an agent (introduced agent) into a cell, the method comprising the step of complexing the introduced agent in the presence of an...
US-1,023,8682 Structure and use of 5' phosphate oligonucleotides
Oligonucleotides bearing free, uncapped 5' phosphate group(s) are recognized by RIG-I, leading to the induction of type I IFN, IL-18 and IL-1.beta. production....
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