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Patent # Description
US-1,023,8681 Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-,...
microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing...
US-1,023,8680 D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
Provided herein are compounds, compositions, and methods for the treatment of viral infections, for example, Flaviviridae infections, including HCV infections....
US-1,023,8679 Antitumor activity of multi-kinase inhibitors in colorectal cancer
A composition for use in the prevention and/or treatment of colorectal cancer in a patient, comprising: a) a compound of Formula (I), where R.sub.1, R.sub.2,...
US-1,023,8678 Therapeutic methods
The present invention features a method for the treatment of Hepatitis C in a human in need thereof comprising administering a compound of Formulas (II) or...
US-1,023,8677 Treatment of filarial diseases
The present invention pertains to prevention of and/or treatment for filariasis. In particular, the present invention pertains to the use of tylosin A and its...
US-1,023,8676 Application of ginsenoside RG3 in preparing medicine for preventing and/or treating dementia, and medicine for...
The present invention discloses an application of ginsenoside Rg3 in preparing a medicine or product for preventing and treating dementia, and a preparation...
US-1,023,8675 Methods for treating pulmonary non-tuberculous mycobacterial infections
Provided herein are methods for treating a pulmonary infection in a patient in need thereof for example, a nontuberculous mycobacterial pulmonary infection for...
US-1,023,8674 Bovine milk oligosaccharides
Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided.
US-1,023,8673 Methods and compositions for treatment of dry eye and correction of organ dysfunctions
The present invention includes compositions and methods for treating certain conditions such as dry eye or dry mouth with a comprising a choline compound; a...
US-1,023,8672 Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions.
US-1,023,8671 Hydrosoluble hydroxybisphosphonic derivatives of doxorubicin
The invention relates to hydrosoluble hydroxybisphosphonic derivatives of doxorubicin of formula (I) and the pharmaceutically acceptable salts thereof. The...
US-1,023,8670 9-aminomethyl minocycline compounds and methods of use thereof in urinary tract infection (UTI) treatment
The invention disclosed herein provides a method for treating urinary tract infection (UTI) using 9-[(2,2-dimethyl-propyl amino)-methyl]-minocycline or a salt...
US-1,023,8669 Methods and materials for treating calcific aortic valve stenosis
This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and...
US-1,023,8668 Co-crystals of tramadol and coxibis
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs/coxibs, processes for preparation of the same and their...
US-1,023,8667 Vitamin D receptor/SMAD genomic circuit gates fibrotic response
The present disclosure provides compositions that include a nanoparticle and a compound that increases the biological activity of the vitamin D receptor (VDR)...
US-1,023,8666 Pharmaceutical compositions and methods
This invention relates the use of cortisol blockers (e.g., glucocorticoid receptor [GR] antagonists) for the treating or preventing viral infections, treating...
US-1,023,8665 Methods for treating fungal infections
Disclosed herein are methods of treating fungal infections in a patient, comprising identifying a patient in need of treatment and administering a ...
US-1,023,8664 Compositions and methods for the repair of myelin
Described are oxysterols, pharmaceutical compositions including the oxysterols, and methods of using the oxysterols and compositions for treating diseases...
US-1,023,8663 Extended-release drug delivery compositions
An extended-release drug delivery composition and method of administering the same is provided. The composition comprises microspheres loaded with a...
US-1,023,8662 Needle assisted jet injection administration of testosterone compositions
The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into...
US-1,023,8661 Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
Disclosed are methods for treating various bacterial infections with (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-- ...
US-1,023,8660 Organic compounds
The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder,...
US-1,023,8659 Fatty liver disease treatment using glucocorticoid and mineralocorticoid receptor antagonists
The present invention provides treatment of fatty liver disease using a class of pyrimidinedione cyclohexyl compounds.
US-1,023,8658 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as p38 MAP kinase inhibitors
There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy,...
US-1,023,8657 Heterocyclic compounds for treating psoriasis
Disclosed herein is a method of treating psoriasis involving the use of compound of formula I and/or a pharmaceutically acceptable salt thereof. ##STR00001##
US-1,023,8656 Combination therapy for cancer
The present invention provides preparation of medicaments for use in treating and methods of treating non-small cell lung cancer in a patient comprising: ...
US-1,023,8655 Dihydroindene and tetrahydronaphthalene compounds
The invention provides compounds of formula I: ##STR00001## and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds...
US-1,023,8654 Benzamides-containing compounds and their use in the treatment of epilepsy
The present invention is directed to benzamide-containing compounds of formula I ##STR00001## or pharmaceutically acceptable salts thereof which inhibit the...
US-1,023,8653 Method of treating metabolic disorders and depression with dopamine receptor agonists
This invention relates to methods and formulations for treating metabolic disorders and depression. In some embodiments, the methods comprise administering a...
US-1,023,8652 Compounds for treatment of cancer
The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present...
US-1,023,8651 Aripiprazole formulations having increased injection speeds
The present invention relates to pharmaceutical compositions comprising a compound of Formula (I) that are useful for the intramuscular delivery of ...
US-1,023,8650 Method of treating cancer associated with a RAS mutation
Disclosed herein are methods of treating a cancer characterized by expressing a mutant form of a RAS protein. Some embodiments relate to treatment of cancer by...
US-1,023,8649 Use of masitinib for treatment of cancer in patient subpopulations identified using predictor factors
A method for treating patients afflicted with cancer, wherein the patients are treated with a compound including tyrosine kinase inhibitor, mast cell inhibitor...
US-1,023,8648 Abuse deterrent opioid/opioid-antagonist transdermal patch
An abuse deterrent transdermal patch comprising a multilaminate. The multilaminate can comprise a first layer comprising an opioid analgesic compound, or a...
US-1,023,8647 Compositions for affecting weight loss
Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is an opioid antagonist and the...
US-1,023,8646 Methods for treating pruritus
The present invention relates to methods for treating pruritus with anti-pruritic compositions.
US-1,023,8645 Lower dosage strength imiquimod formulations and short dosing regimens for treating genital and perianal warts
Pharmaceutical formulations and methods for the topical or transdermal delivery of 1isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine or ...
US-1,023,8643 Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
Methods for the treatment of CNS disorders using combinations of muscarinic activators and inhibitors, and medicaments comprising muscarinic activators and...
US-1,023,8642 Methods for treating neurogenic orthostatic hypotension
The invention relates to methods for treating neurogenic orthostatic hypotension and symptoms thereof using 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine...
US-1,023,8641 Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated...
The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of A.beta. peptide in neural tissue....
US-1,023,8640 Pharmaceutical suspension composition
An aqueous oral liquid pharmaceutical composition system with reduced propensity for agglomeration and phase separation which is particularly amendable to the...
US-1,023,8639 Azophenols as ERG oncogene inhibitors
Selective azophenol inhibitors of a wild type or an altered ERG protein expression are described, where the inhibitors represent a compound of Formula (I) or...
US-1,023,8638 Benzothiazole and benzothiophene compounds
The present invention provides benzothiazole compounds or benzothiophene compounds of Formula I having the structure: wherein X.sup.1, X.sup.2, X.sup.3,...
US-1,023,8637 Modulators of the adenosine A3 receptors
Modulators of adenosin A.sub.3 receptors of formula (I): ##STR00001## And procedure for preparing these compounds. Other objectives of the present invention...
US-1,023,8636 Methods of treating liver disease
The present disclosure relates to a method of preventing and/or treating liver disease comprising administering an ASK1 inhibitor in combination with a FXR...
US-1,023,8635 N-carbamoylated urethane for treating a neuroinflammatory disease
There is provided a composition for treating a neuroinflammatory disease comprising a N-carbamoylated urethane compound which has an effect of inhibiting the...
US-1,023,8634 Aqueous-based metronidazole gel formulations
The present disclosure provides mucoadhesive aqueous-based gel formulations of metronidazole useful for a variety of purposes, including intravaginal...
US-1,023,8633 Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid ...
This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 ##STR00001## and their use as inhibitors of...
US-1,023,8632 Sigma receptor-binding agent
A sigma receptor-binding agent, which comprises an alkyl ether derivative represented by formula [1] or a salt thereof is provided. ##STR00001## wherein...
US-1,023,8631 Sesquiterpene derivatives and their use in inflammation or cancer treatment
A new class of sesquiterpene derivative useful for treating cancerous and inflammatory diseases are disclosed. These deoxyelephantopin derivatives are effective...
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