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Patent # Description
US-1,023,9966 Block copolymer hydride and stretched film formed from same
The present invention is a hydrogenated block copolymer obtained by hydrogenating a block copolymer [C] that comprises polymer blocks [A] and polymer block [B],...
US-1,023,9965 Cyclic olefin resin compositions comprising functional elastomers
This invention relates to compositions and methods for improving the impact properties of polymer-matrix composites and to improving the adhesion of resin...
US-1,023,9964 Method for manufacturing conjugated diene polymer, conjugated diene polymer, rubber composition, and tire
A method for manufacturing a conjugated diene polymer that can increase the robustness of a polymerization reaction system is provided. Also, a conjugated diene...
US-1,023,9963 Mixed salt suspension polymerization process and resins and catalysts produced thereof
This invention relates to no-salt and mixed salt suspension polymerization processes for water-soluble monomers and resins and relates to catalysts produced...
US-1,023,9962 Hyaluronic acid derivatives
The present disclosure relates to hyaluronic acid derivatives, and in particular, derivatives in which the N-acetyl group of hyaluronic acid has been...
US-1,023,9961 Cyclodextrin
The invention provides a method for preparing sulphoalkyl ether-.beta.-cyclodextrin. The method comprises first contacting cyclodextrin with a base to form...
US-1,023,9960 Phosphonated polysaccharides and gels and process for making same
Products and processes that are related to phosphonated polysaccharide compositions, including phosphonated polysaccharide gels, having a substituent degree of...
US-1,023,9959 Acylation process
The invention concerns a process for the manufacture of an acylated polymer composition comprising amylose and/or amylopectin, comprising a pre-treatment step...
US-1,023,9958 Process for modifying starches
A process for modifying starch comprises atomising an aqueous slurry of non-pregelatinised starch into an internal chamber in a bi-fluid nozzle of a spray dryer...
US-1,023,9957 Peptide containing conjugates for dual molecular delivery of oligonucleotides
Disclosed herein is a peptide containing conjugate comprising (P).sub.c-(L).sub.d-(G).sub.e, wherein P is a peptide and each occurance of P is independently...
US-1,023,9956 Nucleic acid encoding bone marrow stromal antigen 1 antibody
The invention provides antibodies which bind to the ADP-ribosyl cyclase 2. Nucleic acid molecules encoding the antibodies, expression vectors, host cells and...
US-1,023,9955 Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase
Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical...
US-1,023,9954 Antibodies specific for urokinase-type plasminogen activator and methods of use thereof for treating cancer
The present disclosure relates to antibodies specific for urokinase-type plasminogen activator (uPA). According to certain embodiments, the anti-uPA antibody...
US-1,023,9953 Dual targeting of TAFI and PAI-1
Disclosed herein is a bispecific inhibitor for use in treating thrombotic disorders, such as acute thrombotic disorders like stroke and thromboembolism. The...
US-1,023,9952 Anti-WT1/HLA bi-specific antibody
Disclosed herein is a bi-specific form of a T cell receptor mimic (TCRm) mAb with reactivity to human immune effector cell antigen and a WT1 peptide/HLA-A...
US-1,023,9951 Bispecific HER2 and HER3 antigen binding constructs
Described herein are isolated bi-specific antigen binding constructs, e.g., antibodies. The bi-specific antigen binding constructs include two antigen binding...
US-1,023,9950 Anti-MUC1 antibody or antigen-binding fragment thereof and uses thereof
The present invention provides: an antibody exhibiting specificity for MUC1, the antibody having a glycan structure expressed at high levels in cancer cells; a...
US-1,023,9949 Oncofetal antigen binding proteins and related compositions and methods
The present disclosure relates to protein molecules that specifically bind to 5T4 and/or 4-1BB. The molecules may have at least one humanized 5T4-binding or...
US-1,023,9948 Method of engineering multi-input signal sensitive T cell for immunotherapy
The present invention relates to a method to engineer immune cell for immunotherapy. In particular said immune cells are engineered with chimeric antigen...
US-1,023,9947 Anti-CLL-1 antibodies and immunoconjugates
The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
US-1,023,9946 Cell line overexpressing human CD303 antigen
The invention relates to a cell line expressing the gamma chain of the Fc.epsilon.RI receptor and human CD303 antigen, characterized in that said cell line is...
US-1,023,9945 Therapeutic CD47 antibodies
Provided are anti-CD47 monoclonal antibodies (anti-CD47 mAbs) with distinct functional profiles as described herein, methods to generate anti-CD47 mAbs, and to...
US-1,023,9944 Compositions and methods related to engineered Fc constructs
The present invention relates to compositions and methods of engineered IgG Fc constructs, wherein said Fc constructs include one or more Fc domains.
US-1,023,9943 Treatment of eosinophil or mast cell related disorders
Provided herein are methods and uses involving antibodies that specifically bind to a KIT receptor tyrosine kinase for managing, treating, or preventing an...
US-1,023,9942 Anti-PD-1 antibodies
Antibodies that bind to programmed cell death protein 1 (PD-1), compositions comprising such antibodies, and methods of making and using such antibodies are...
US-1,023,9941 Anti-hepcidin antibodies and uses thereof
The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which...
US-1,023,9940 Method of promoting bone growth by an anti-actriia antibody
In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density.
US-1,023,9939 Anti-ED-A immunoconjugates for inflammatory bowel disease
Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel...
US-1,023,9938 T-cell redirecting bispecific antibodies for treatment of disease
The present invention concerns compositions and methods of use of T-cell redirecting complexes, with at least one binding site for a T-cell antigen and at least...
US-1,023,9937 Treatment of paroxysmal nocturnal hemoglobinuria, hemolytic anemias and disease states involving intravascular...
Methods for treating subjects having complement-mediated hemolytic disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) and other hemolytic anemias, the...
US-1,023,9935 Human immunodeficiency virus neutralizing antibodies
The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
US-1,023,9934 Monoclonal antibodies directed against trimeric forms of the HIV-1 envelope glycoprotein with broad and potent...
The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for...
US-1,023,9933 Compositions and methods for modulating thrombin generation
Factor V peptides and methods of use thereof are disclosed.
US-1,023,9932 Uterine cancer treatments
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,9931 Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and...
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,9930 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,9929 Peptide analogs for treating diseases and disorders
Provided herein are methods for the treatment of type I diabetes, Type II diabetes, metabolic syndrome, or obesity, or of appetite suppression, or for...
US-1,023,9928 Method of highly expressing target protein from plant using RbcS fusion protein and method of preparing...
The present invention provides a plant expressing a target protein, a method of preparing the same and a method of preparing a composition for oral...
US-1,023,9927 Peptides and compositions for treatment of joint damage
The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions...
US-1,023,9926 Compositions and methods for vascular protection against reperfusion injury after myocardial ischemia
As described herein, the present invention features compositions comprising an HGF/IgG complex and methods of using such compositions to reduce ischemic...
US-1,023,9925 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,023,9924 Peptide having eight amino acid sequences derived from cage and retaining anticancer activity and activity to...
A peptide having eight amino acid sequences derived from cancer-associated gene (CAGE) is described which retains anticancer activity and activity to promote...
US-1,023,9923 Specific amyloid beta binding peptides and the use of same for treating and diagnosing alzheimer's dementia
Peptides specifically binding amyloid beta and to methods of treating and diagnosing Alzheimer's dementia using such peptides are provided.
US-1,023,9922 Fusion proteins of superfolder green fluorescent protein and use thereof
The present disclosure pertains to methods of producing recombinant peptides that contain between 10 and 200 amino acid residues using novel carrier proteins...
US-1,023,9921 Insecticidal proteins
Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at...
US-1,023,9920 Cupredoxin derived transport agents and methods of use thereof
The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the...
US-1,023,9919 Selective delivery molecules and methods of use
Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells...
US-1,023,9918 Cahuitamycins and methods of making and using the same
Provided herein are biofilm inhibitors obtained from marine microbial derived natural product extracts from Streptomyces gandocaensis, resulting in biofilm...
US-1,023,9916 Controlled modulation of amino acid side chain length of peptide antigens
The invention provides a method for the creation of peptide antigens comprising epitopes with at least a first modification comprising a shortened or lengthened...
US-1,023,9915 Method for continuous production of degradation product of water-insoluble polymeric compound
This invention is intended to produce a novel functional material through solubilization and molecular weight reduction of a water-insoluble polymeric compound,...
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