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Patent # Description
US-1,025,3122 Ethylene-1-hexene-1-butene terpolymer and a film including the same
The present invention relates to ethylene-1-hexene-1-butene terpolymer and a film including the same. The ethylene-1-hexene-1-butene terpolymer according to the...
US-1,025,3121 Method of producing polyethylene and polyethylene thereof
A system and method of producing polyethylene, including: polymerizing ethylene in presence of a catalyst system in a reactor to form polyethylene, wherein the...
US-1,025,3120 Steam barrier resin, steam barrier coating agent, steam barrier film, and steam barrier laminate
The present invention provides as steam barrier resin, a steam barrier coating agent, a steam barrier film, and a steam barrier laminate that exhibit an...
US-1,025,3119 Method for preparing conjugated diene-based polymer
The present invention provides a method for preparing a conjugated diene-based polymer including preparing a mixture of a molecular weight modifier and a...
US-1,025,3118 Cyanine coloring composition
It is an object of the present invention to provide a cyanine-based coloring composition having higher heat resistance, as compared with a conventional coloring...
US-1,025,3117 Process for producing diene polymers
The invention describes a process for producing a diene polymer, the process including the following steps in this order i) polymerizing one or more diene...
US-1,025,3116 Process for the preparation of diene polymers or random vinyl arene-diene copolymers
Process for the preparation of a diene polymer or a random vinyl arene-diene copolymer comprising anionically (co)polymerizing at least one conjugated diene...
US-1,025,3115 Process for the manufacture of a capacitor film
Process for producing of a capacitor film comprising the steps of (a) polymerizing propylene in the presence of a catalyst comprising a solid catalyst system...
US-1,025,3114 Polyolefin modified with nitrogen-containing heterocyclic compound, and adhesive composition containing same
This invention provides a novel polyolefin modified with a nitrogen-containing heterocyclic compound containing no harmful halogen atoms such as chlorine, and...
US-1,025,3113 Method for activation of chromium containing catalyst precursor for polymerization and the resulting...
Method for activation of chromium containing catalyst precursor for polymerization and improved polymerization catalyst resulting The instant invention relates...
US-1,025,3112 Soft silicone medical devices
The invention is related to a method for producing silicone medical devices, in particular, silicone contact lenses, having consistent mechanical properties in...
US-1,025,3111 Methods and compositions relating to anti-Chi3l1 antibody reagents
Described herein are methods and compositions relating to anti-Chi3L1 antibodies, antibody reagents, and antigen-binding fragments thereof which display...
US-1,025,3110 Anti-FAP antibodies and methods of use
The invention provides antibodies against Fibroblast Activation Protein (FAP) and methods of using the same.
US-1,025,3109 Antibodies that recognize red blood cell antigens
Compositions and methods of using antibodies that are able to recognize single amino acid polymorphisms in a protein are provided. Compositions are disclosed...
US-1,025,3108 Mutated antibody of fully humanized HER2 antibody, and encoding gene and use thereof
The present invention provides a mutated antibody of the fully humanized HER2 antibody GB235-019, wherein the amino acid sequence of the heavy chain variable...
US-1,025,3107 Use of endocytosis inhibitors and antibodies for cancer therapy
The present invention relates to the use of endocytosis inhibitors, including clathrin-dependent endocytosis inhibitors such as inhibitors of dynamin and...
US-1,025,3106 Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells
This invention relates to the use of monoclonal and polyclonal antibodies that specifically bind to and have the ability in the alternative to become...
US-1,025,3105 Bispecific antibody binding to human TLR2 and human TLR4
The present application provides a bispecific antibody for preventing or treating an immune inflammatory disease by acting on both human TLR2 and human TLR4 to...
US-1,025,3104 Bispecific antibodies against CD3 and BCMA
A bispecific bi- or trivalent antibody specifically binding to the two targets which are extracellular domain of human B cell maturation antigen (BCMA) and...
US-1,025,3103 Antibody specifically binding to GLP-1R and fusion protein thereof with GLP-1
Disclosed in the present invention is an antibody specifically binding to GLP-1R and a fusion protein thereof with GLP-1. The fusion proteins can effectively...
US-1,025,3102 Antigen-binding proteins that activate the leptin receptor
The present invention provides antibodies and antigen-binding fragments of antibodies that bind to leptin receptor (LEPR), and methods of using the same....
US-1,025,3101 Antibody fragments against the insulin receptor and uses thereof to treat hypoglycemia
The present disclosure relates, in general, to methods of treating or preventing hypoglycemia using a negative modulator antibody fragment that binds to the...
US-1,025,3100 Therapeutic antigen-binding molecule with a FcRn-binding domain that promotes antigen clearance
The present invention provides: a modified FcRn-binding domain having an enhanced affinity for the Fc Receptor neonatal (FcRn) at neutral pH; an antigen-binding...
US-1,025,3099 Conjugates of proteins and multivalent cell-penetrating peptides and their uses
The present invention relates to conjugates comprising a protein and multivalent cell-penetrating peptide(s), each multivalent cell-penetrating peptide...
US-1,025,3098 Glyco-engineered antibodies
The present invention relates to an antibody preparation comprising modified antibodies of an animal or derivatives or fragments thereof, specific for an...
US-1,025,3097 Isolated antibody
An antibody capable of potentiating immune responses and modifying existing states of immune responsiveness is described, as is the sequence of the antibody....
US-1,025,3096 Anti-Tim-3 antibodies
The present invention relates to antibodies that bind human T-cell immunoglobulin- and mucin-domain-containing protein-3 (Tim-3), and may be useful for treating...
US-1,025,3095 Anti-KIR combination treatments and methods
Compositions comprising anti-KIR antibodies and one or more secondary anti-cancer agents or anti-viral agents and methods of using such combinations (as...
US-1,025,3094 Antibodies that target human protein tyrosine phosphatase-beta (HPTP-beta) and methods of use thereof to treat...
The disclosure provides compositions and methods for the treatment of ocular conditions associated with angiogenesis comprising administering an antibody that...
US-1,025,3093 Human monoclonal antibodies against interleukin 8 (IL-8)
Isolated human monoclonal antibodies which bind to IL-8 (e.g., human IL-8) are disclosed. The human antibodies can be produced in a hybridoma, transfectoma or...
US-1,025,3092 Medicament and apparatus for treating chronic kidney disease
The present invention provides a novel therapy concept based on a removal of circulation BSP (bone sialoprotein) from the plasma of patients with chronic kidney...
US-1,025,3090 Hydrolyzed collagen compositions and methods of making thereof
Disclosed herein are hydrolyzed collagen compositions. The compositions are inexpensive to make and can be produced without the use of proteolytic enzymes,...
US-1,025,3089 Matrix metalloproteinase cleavable protein polymers for cancer gene therapy
A delivery system that includes a recombinantly synthesized protein polymer with protease cleavage sites such as matrix metalloproteinase responsive sequences...
US-1,025,3088 Modified von Willebrand Factor
The present invention provides a modified polypeptide which binds Factor VIII. The modified polypeptide comprises a sequence as shown in SEQ ID NO:3 in which...
US-1,025,3087 CCR2 antagonist peptides
The invention relates to a peptide useful as a CCR2 non-competitive antagonist peptide.
US-1,025,3086 CD20 therapies, CD22 therapies, and combination therapies with a CD19 chimeric antigen receptor...
The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising...
US-1,025,3085 CD31 peptides for the treatment of thrombotic or autoimmune disorders
The present invention stems from the finding that the extracellular domain of CD31 proteins present on blood leukocytes is shed and released in the circulation...
US-1,025,3084 Methods for predicting three-dimensional structures for alpha helical membrane proteins and their use in design...
A method for practical prediction of the three-dimensional structure of .alpha.-helical membrane proteins (HMPs) is described. The method allows one to predict...
US-1,025,3083 Therapeutic uses of modified relaxin polypeptides
Therapeutic uses of modified relaxin polypeptides for the treatment of cardiovascular disease, treatment of heart failure, and decreasing fibrotic disorders are...
US-1,025,3082 Long-acting insulin and use thereof
The present invention relates to an insulin analog that has reduced insulin receptor binding affinity for the purpose of increasing the blood half-life of...
US-1,025,3081 Glucagon analogues
The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders. In particular,...
US-1,025,3080 Glucagon-like-peptide-2 (GLP-2) analogues
GLP-2 analogs are disclosed which comprise one of more substitutions as compared to h[Gly2]GLP-2 and which may have the property of an altered GLP-1 activity,...
US-1,025,3079 Functionalized Exendin-4 derivatives
The present invention relates to exendin-4 derivatives and their medical use, for example in the treatment of disorders of the metabolic syndrome, including...
US-1,025,3078 GIP agonist compounds and methods
The present invention relates to acylated GIP analogs which have GIP agonist activity, and their use in the treatment of metabolic disorders.
US-1,025,3077 Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,025,3076 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
US-1,025,3075 WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide
[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against...
US-1,025,3074 Nontoxigenic Clostridium botulinum strains and uses thereof
A mutant strain of the bacterium Clostridium botulinum having an inactivated botulinal neurotoxin gene is disclosed. The mutant strain contains an artificially...
US-1,025,3073 Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
Epitopes derived from human papilloma virus and peptides having a size of about 22-45 amino acid residues comprising minimal T cell epitopes are disclosed. Also...
US-1,025,3072 Prophylactic vaccine against egg drop syndrome (EDS)
The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The...
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