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Patent # Description
US-1,029,2991 Small molecule therapeutic compounds that reduce the incidence of intracerebral hemorrhage and brain...
The described invention relates to small molecule therapeutic compounds capable of reducing the incidence of intracerebral hemorrhage and brain microhemorrhages...
US-1,029,2990 Abiraterone steroid formulation
A nanoparticulate composition of abiraterone acetate that allows treatment at a lower dose than convention abiraterone acetate formulations is described as in a...
US-1,029,2989 General anesthetics that are not neurotoxic
The present application discloses the unexpected result that a neuroactive steroid such as B260 can act as a general anesthetic and that it has no neurotoxic...
US-1,029,2988 Applications for estrone in preparing anti-ovarian cancer and/or breast cancer products
This invention discloses uses for estrone in preparing anti-ovarian cancer and/or breast cancer products. This invention provides uses for estrone in the...
US-1,029,2987 Heterocyclic amides as kinase inhibitors
Disclosed are compounds having the formula: ##STR00001## wherein X, Y, Z.sup.1, Z.sup.2, Z.sup.3, Z.sup.4, R.sup.5, R.sup.A, m, A. L, and B are as defined...
US-1,029,2986 Methods for treating epithelian mesenchymal transition related diseases
Certain embodiments are directed to methods of treating chronic lung diseases in a subject comprising administering to a subject diagnosed with, exhibiting...
US-1,029,2985 TGF beta receptor antagonists
The invention relates generally to compounds that modulate the activity of TGFBETA R-1 and TGFBETA R-2, pharmaceutical compositions containing said compounds...
US-1,029,2984 Methods for increasing blood plasma 2'-deoxyuridine (dUrd) and thymidylate synthase inhibition
The present invention provides methods for increasing plasma dUrd levels comprising the administration of 6R-MTHF. The methods of increasing plasma dUrd...
US-1,029,2983 Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
Use of oxymethylene aryl GPR119 agonists, and optionally DPP IV inhibitors and optionally metformin, for the treatment of inflammatory gastrointestinal diseases...
US-1,029,2982 Inhibitors of multidrug resistance transporter P-glycoprotein
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant...
US-1,029,2981 Oxazoline and isoxazoline derivatives as CRAC modulators
The present invention relates to compounds of Formula (I), ##STR00001## along with processes for their preparation that are useful for treating, preventing...
US-1,029,2980 GAPDH cascade inhibitor compounds and methods of use and treatment of stress induced disorders including mental...
In DN-DISC1 mice, a mouse model for major mental illnesses, the model that expresses pathological phenotypes relevant to schizophrenia, mood disorders, and...
US-1,029,2979 Methods of treating cancer patients with farnesyltransferase inhibitors
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject...
US-1,029,2978 Specific Akt3 inhibitor and uses thereof
Methods of selectively inhibiting Akt3 are provided. It has been discovered that 4-[(6-nitroquinolin-4-yl)amino]-N-[4-(pyridin-4-ylamino)phenyl]benzamide ...
US-1,029,2977 Compositions and methods for treatment related to fall and fall frequency in neurodegenerative diseases
The present disclosure provides methods and compositions for treating fall-related symptoms in patients with neurodegenerative diseases such as Parkinson's...
US-1,029,2976 Anti-malarial agent
The present invention aims to prevent and/or treat malaria using an antimalarial drug comprising, as an active ingredient, a metal chelator represented by the...
US-1,029,2975 Compounds as rearranged during transfection (RET) inhibitors
This invention relates to novel compounds which are inhibitors of the Rearranged during Transfection (RET) kinase, to pharmaceutical compositions containing...
US-1,029,2974 Prophylactic or therapeutic agent for giant cell tumors occurring in bone and soft tissue or for chondrosarcoma
The present invention provides a prophylactic or therapeutic agent for giant cell tumors occurring in a bone and soft tissue or for chondrosarcoma, which...
US-1,029,2973 Covalent irreversible inhibitors of USP7 as anti-cancer agents
Compounds and pharmaceutical compositions for treating cancer by, for example, modulating immune system activity, are provided.
US-1,029,2972 Pharmaceutical composition for treating cancer and a method thereof
A pharmaceutical composition containing an anticancer compound, named isopicrinine, isolated from the plant Rhazya Stricta. The pharmaceutical composition may...
US-1,029,2971 Tetrahydro-1H-pyrido[3,4-b]indole anti-estrogenic drugs
The present disclosure provides tetrahydro-1H-pyrido[3,4-b]indole compounds or a pharmaceutically acceptable salt, solvate, hydrate, prodrug, stereoisomer,...
US-1,029,2970 Heteroaryl-substituted imidazo[1,2-A]pyridines and their use
The present application relates to novel heteroaryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in...
US-1,029,2969 Composition for prevention or treatment of bronchial asthma comprising PKR inhibitor as active ingredient
The present invention relates to a composition for prevention or treatment of bronchial asthma comprising a PKR inhibitor as an active ingredient. The PKR...
US-1,029,2968 Substituted heterocycles as bromodomain inhibitors
The present application relates to substituted heterocycles compound of Formula I and pharmaceutical compositions thereof useful for the inhibition of BET...
US-1,029,2967 Compositions comprising corneoscleral tissue cross-linking agents
A composition for opththalmic administration comprising a formaldehyde releasing agent, sodium bicarbonate, and an ophthalmically suitable carrier or excipient...
US-1,029,2966 Sustained release pharmaceutical compositions
The present invention provides controlled release dosage formulations of compounds having the Formula: ##STR00001## or pharmaceutically acceptable salts...
US-1,029,2965 Nintedanib diethanesulfonate salt crystal and preparation method and use thereof
The present invention relates to a nintedanib diethanesulfonate salt A-type crystal represented by formula (II), and also relates to a crystalline composition...
US-1,029,2964 Compositions for increasing human growth hormone levels
Embodiments of the invention generally relate to supplements for increasing human growth hormone (hGH) levels in healthy human beings.
US-1,029,2963 Suppression and treatment of viruses
Combinations of betaine and vitamin C are used to suppress or prevent malignant tumors or to treat viruses, e.g., by combining the two ingredients in a product...
US-1,029,2962 Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer
Provided is a novel medicament capable of reducing the side effects of metformin or a pharmaceutically acceptable salt thereof and useful as an anti-malignant...
US-1,029,2961 Disulfur bridge linkers for conjugation of a cell-binding molecule
The present invention relates to novel disulfur bridge linkers containing hydrazine used for the specific conjugation of compounds/cytotoxic agents to a...
US-1,029,2960 Anticancer agent comprising aminoacetonitrile compound as active ingredient
The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and an anticancer agent containing, as an active...
US-1,029,2959 Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant...
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in...
US-1,029,2958 Lipid-containing compositions and methods of use thereof
Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed...
US-1,029,2957 Compositions and methods for treating fibromyalgia
Embodiments of the invention generally relate to supplements for treating fibromyalgia and symptoms associated with fibromyalgia.
US-1,029,2956 Cancer starvation therapy
The present invention is a glutamine compound having a high Z element attached via a ligand, which enters the mitochondrion and is subsequently exposed to...
US-1,029,2955 Composition for external use preparation with improved transdermal permeability
Provided is a skin external composition, which includes tranexamic acid or a salt thereof and a skin penetration enhancer, thereby showing remarkably increased...
US-1,029,2954 Composition and method for muscle repair and regeneration
The invention provides methods for muscle repair or regeneration comprising administering therapeutically effective amounts of RAR agonists or stem cells that...
US-1,029,2953 Pharmaceutical composition of ibuprofen and tramadol for ophthalmic use
The present invention relates to a pharmaceutical composition of ibuprofen and tramadol for ophthalmic use. Said composition is effective and safe for the...
US-1,029,2952 Mixed salt compositions for maintaining or restoring electrolyte balance while producing elevated and sustained...
Ketogenic compositions including a beta-hydroxybutyrate (BHB) mixed salt are formulated to induce or sustain ketosis in a subject to which the ketogenic...
US-1,029,2951 Methods and compositions for treating conditions associated with an abnormal inflammatory responses
This disclosure features chemical entities (e.g., a compound exhibiting activity as a mitochondrial uncoupling agent or a pharmaceutically acceptable salt...
US-1,029,2950 Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing
Disclosed herein are compounds, pharmaceutical compositions, and methods for the treatment of diseases such as inflammation and/or pain, comprising the...
US-1,029,2949 Pharmaceutical composition comprising rimeporide for treating diseases associated with insulin resistance and...
The invention relates to a pharmaceutical composition comprising as active ingredient an effective amount of 2-Methyl-4,5-di-(methylsulfonyl)-benzoyl-guanidine,...
US-1,029,2948 Tapentadol nasal composition
Disclosed herein are pharmaceutical compositions for nasal administration comprising tapentadol, their preparation and their use in the treatment of pain.
US-1,029,2947 Pharmaceutical compositions for N-propargylamine derivative
The present application relates to a method of treating Parkinson's disease by administering a mouth-dissolving composition of N-propargylamine derivative, such...
US-1,029,2946 Antimicrobials and methods of use thereof for wound healing
This disclosure provides generally for antimicrobial compositions and methods of use comprising an anthocyanin, an anthocyanidin or metabolites thereof. Methods...
US-1,029,2945 Dressings that contain active substance
A dressing for applying to the skin is characterized in that the adhesive mass is applied discontinuously in a strip or wave and contains an active substance.
US-1,029,2944 Systems and methods for feeding sugar alcohol to ruminants during periods of heat stress
Systems and methods provide sugar alcohol to heat stressed ruminants to improve performance. During periods of high temperature or humidity, heat stressed...
US-1,029,2943 Delivery of bioactive, nanoencapsulated antioxidants
Methods and compositions are disclosed for delivering lutein or other antioxidant to target tissues such as the eye, in bioactive form, while protecting the...
US-1,029,2942 Transdermal therapeutic system comprising active ingredient particles and having increased active ingredient flux
The invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of...
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