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Patent # Description
US-1,029,4521 Method of extending DNA with telomerase and method of measuring telomerase activity
The present disclosure provides a measurement method of telomerase activity with no occurrence of false-negative and high quantitative capability. In the...
US-1,029,4520 Nicotiana nucleic acid molecules and uses thereof
The present invention features Nicotiana nucleic acid sequences such as sequences encoding constitutive, or ethylene or senescence induced polypeptides, in...
US-1,029,4519 Method and apparatus for nucleic acid analysis
A convenient method for nucleic acid analysis is provided, which enables 1000 or more types of nucleic acid to be analyzed collectively with high ...
US-1,029,4518 Methods and systems for ultra-sensitive detection of genomic alterations
The invention discloses methods and apparatuses for the detection and diagnostics of genetic alterations/mutations in a target sample, which may be a solid...
US-1,029,4517 Genetic test for determining susceptibility for eosinophilic esophagitis
Methods and compositions disclosed herein generally relate to determination of susceptibility to eosinophilic esophagitis, asthma, and/or allergic diseases,...
US-1,029,4516 Enhanced probe binding
Methods for enhancing the binding of oligonucleotide probes to DNA and RNA are disclosed. The methods make use of thermodynamic and kinetic effects to reduce...
US-1,029,4515 Methods of detecting gene fusions
Disclosed herein are methods of detecting presence of a gene fusion in a sample from a subject. In some embodiments, the methods of detecting presence of a...
US-1,029,4514 Sequencing method employing ternary complex destabilization to identify cognate nucleotides
Provided are methods and systems for detecting formation of nucleotide-specific ternary complexes comprising a DNA polymerase, a nucleic acid, and a nucleotide...
US-1,029,4513 Preservation of cell-free nucleic acids
A method for preserving and processing cell-free nucleic acids located within a blood sample is disclosed, wherein a blood sample containing cell-free nucleic...
US-1,029,4512 Method and apparatus for analyzing biomolecules by using oligonucleotide
The present invention relates to a method for analyzing biomolecules by using an oligonucleotide, and specifically, provides a method and an apparatus for...
US-1,029,4511 Methods and compositions for preparing nucleic acid libraries
Embodiments provided herein relate to methods and compositions for preparing nucleic acid libraries. Some embodiments include preparing libraries from nucleic...
US-1,029,4510 High-throughput and highly multiplexed imaging with programmable nucleic acid probes
The present invention provides, inter alia, methods and compositions for imaging, at high spatial resolution, targets of interest.
US-1,029,4508 Method and apparatus for identification of bacteria
An automated system for identifying in a biological sample microorganisms and their antimicrobial susceptibility (AST). The system provided an automated...
US-1,029,4507 Glucose sensors and methods of manufacture thereof
Disclosed herein is a device that functions as a glucose sensor. The device has a reference electrode; a counter electrode, a working electrode; an electrically...
US-1,029,4506 Methods for producing biological materials
Methods of producing biological materials from cells and organisms are provided. Aspects of the methods include modulating the stress conditions of the cells...
US-1,029,4505 Microorganism for production of chemicals derived from acetyl-CoA
Disclosed is an acetyl-CoA-producing microorganism, which is obtained by imparting malate thiokinase and malyl-CoA lyase enzymatic activities to a microorganism...
US-1,029,4504 Mutant endoglycoceramidases with enhanced synthetic activity
The present invention relates to a novel endoglycoceramidase whose hydrolytic activity has been substantially reduced or eliminated, such that the enzyme is...
US-1,029,4503 Processing biomass
Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane, a...
US-1,029,4502 Methods for the synthesis of chiral kynurenine compounds
Provided are methods for synthesizing compounds, including chiral kynurenine compounds. The methods are suitable for large-scale manufacture and produce the...
US-1,029,4501 Method for producing oxo fatty acid and rare fatty acid
The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid,...
US-1,029,4500 Method for producing methacrylic acid and/or ester thereof
To provide a method for directly and efficiently producing methacrylic acid in a single step from renewable raw materials and/or biomass arising from the...
US-1,029,4499 Biosynthesis of phenylpropanoids and phenylpropanoid derivatives
Provided herein are recombinant hosts and methods for producing phenylpropanoid and phenylpropanoid derivative compounds. It was found that tyrosine ammonia...
US-1,029,4498 Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
The invention provides a non-naturally occurring bacterium having decreased or eliminated activity of an enzyme that catalyzes the reaction defined by EC...
US-1,029,4497 Highly efficient ethanol-fermentation yeast
An object of the present invention is to obtain fermentative yeast having highly efficient ethanol production without introducing a foreign gene. A further...
US-1,029,4496 Methods for biosynthesizing 1,3 butadiene
This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described...
US-1,029,4495 Fermented mineral raw-edible pill with constipation reduction and fatigue recovery and method for producing the...
The invention relates to a method for producing a fermented mineral pill with constipation reduction and fatigue recovery, the method comprising: cultivating...
US-1,029,4494 Methods and compositions for modifying a targeted locus
Methods and compositions are provided for modifying one or more target loci in a cell. Such methods comprise providing a cell comprising a first polynucleotide...
US-1,029,4493 Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same
A subgroup B recombinant human adenovirus vector Ad11-5EP (SEQ ID NO: 1), which is constructed by a method including: substituting a 365 bp fragment containing...
US-1,029,4492 Stable episomes based on non-integrative lentiviral vectors
The invention relates to non-integrative lentiviral vectors and their use for the stable transgenesis of both dividing and no-dividing eukaryotic cells. The...
US-1,029,4491 Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
The present invention relates to expression vectors for the heterologous expression of a nucleic acid sequence of interest in mammalian cells, the vectors...
US-1,029,4490 Insecticidal proteins and methods for their use
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal...
US-1,029,4489 Soybean resistant to cyst nematodes
A transgenic soybean plant or parts thereof, resistant to soybean cyst nematodes, transformed to express Glyma18g02570, Glyma18g02580, or Glyma18g02590, or a...
US-1,029,4488 Herbicide-metabolizing cytochrome P450 monooxygenases
The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding...
US-1,029,4487 Methods and compositions involving ALS variants with native substrate preference
Compositions and methods comprising polynucleotides and polypeptides having ALS activity and tolerance to at least one ALS inhibitor are provided. In specific...
US-1,029,4486 Compositions and methods for altering flowering and plant architecture to improve yield potential
The present invention provides recombinant DNA constructs, vectors and molecules comprising a polynucleotide sequence encoding a florigenic FT protein operably...
US-1,029,4485 Plant promoter and 3' UTR for transgene expression
This disclosure concerns compositions and methods for promoting transcription and translation of a nucleotide sequence in a plant or plant cell, employing a...
US-1,029,4484 Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch,...
US-1,029,4483 Eimeria tenella elongation factor-1 alpha recombinant immunogenic compositions which induce active protective...
Provided herein are immunogenic compositions containing recombinant proteins capable of presenting all, or antigenic portions of, the Eimeria tenella Elongation...
US-1,029,4482 Recombinant microorganisms capable of carbon fixation
A microorganism which is genetically modified so that it produces a first essential biomass precursor by metabolizing CO.sub.2 using a recombinant carbon...
US-1,029,4481 Microbial production of renewable glycolate
Some aspects provide engineered microbes for glycolate production. Methods for microbe engineering and culturing are also provided herein. Such engineered...
US-1,029,4480 Foreign DNA surveillance protein
A method for augmenting expression of a heterologous nucleic acid in a eukaryotic cell or increasing the efficiency of gene expression using any gene expression...
US-1,029,4479 Candida carbonyl reductase and method for preparing (R)-lipoic acid precursor
Disclosed herein is Candida parapsilosis CGMCC 9630, the carbonyl reductase expressed by said strain and the encoding gene and amino acid sequence thereof, the...
US-1,029,4478 Aptamer modulators of estrogen receptors
The present invention relates to a nucleic acid aptamer molecule that includes a domain that binds to an estrogen receptor, molecular complexes that include the...
US-1,029,4477 Compositions and methods for modulating PKK expression
Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to...
US-1,029,4476 NEAT1 as a prognostic marker and therapeutic target for prostate cancer
This invention relates to diagnosis and prognosis of prostate cancer, as well as therapeutic treatment of prostate cancer. More specifically, the invention...
US-1,029,4475 Paratransgenic system for the biocontrol of disease-transmitting mosquitos
The inventive technology relates to novel paratransgenic strategies for the control of pathogens. The inventive technology may specifically include a novel...
US-1,029,4474 Targeting ligands
Described are novel targeting ligands that may be linked to compounds, such therapeutic compounds that are useful in directing the compounds to the in vivo...
US-1,029,4473 Methods for generating barcoded combinatorial libraries
Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive...
US-1,029,4472 Nucleic acid linker
The present invention relates to a nucleic acid linker for producing a complex of mRNA, and a protein or a peptide which is encoded by the mRNA, the linker...
US-1,029,4471 Method of isolating aptamers for minimal residual disease detection
A method for selecting and isolating aptamers that target M-Ig proteins with a microdevice including at least a first selection chamber is provided. The method...
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